Search Results - "Barcus, Craig E."

DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs by Bayer, Samantha Vh, Grither, Whitney R, Brenot, Audrey, Hwang, Priscilla Y, Barcus, Craig E, Ernst, Melanie, Pence, Patrick, Walter, Christopher, Pathak, Amit, Longmore, Gregory D

“…Biomechanical changes in the tumor microenvironment influence tumor progression and metastases. Collagen content and fiber organization within the tumor stroma…”
Get full text

Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells by Barcus, Craig E, Holt, Elizabeth C, Keely, Patricia J, Eliceiri, Kevin W, Schuler, Linda A

“…Breast cancers that express estrogen receptor alpha (ERα+) constitute the majority of breast tumors. Estrogen is a major driver of their growth, and targeting…”
Get full text

Collagen Linearization within Tumors by Barcus, Craig E, Longmore, Gregory D

“…It is now well appreciated that the tumor microenvironment (TME) surrounding primary tumors impacts tumor growth, progression (invasion and migration), and…”
Get full text

Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis by Barcus, Craig E, Hwang, Priscilla Y, Morikis, Vasilios, Brenot, Audrey, Pence, Patrick, Clarke, Maria, Longmore, Gregory D

“…Both tumor cell-intrinsic signals and tumor cell-extrinsic signals from cells within the tumor microenvironment influence tumor cell dissemination and…”
Get full text

Stiff Collagen Matrices Increase Tumorigenic Prolactin Signaling in Breast Cancer Cells by Barcus, Craig E., Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.

“…Clinically, circulating prolactin levels and density of the extracellular matrix (ECM) are individual risk factors for breast cancer. As tumors develop, the…”
Get full text

Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells by Barcus, Craig E, O'Leary, Kathleen A, Brockman, Jennifer L, Rugowski, Debra E, Liu, Yuming, Garcia, Nancy, Yu, Menggang, Keely, Patricia J, Eliceiri, Kevin W, Schuler, Linda A

“…The development and progression of estrogen receptor alpha positive (ERα+) breast cancer has been linked epidemiologically to prolactin. However, activation of…”
Get full text

Prolactin signaling through focal adhesion complexes is amplified by stiff extracellular matrices in breast cancer cells by Barcus, Craig E, Keely, Patricia J, Eliceiri, Kevin W, Schuler, Linda A

“…Estrogen receptor α positive (ERα+) breast cancer accounts for most breast cancer deaths. Both prolactin (PRL) and extracellular matrix (ECM) stiffness/density…”
Get full text

Glioblastoma cancer stem cell properties and synthetic biomaterials by Barcus, Craig E

“…Cancer stem cells serve as the initiating cells of some tumors, with self-renewing and differentiation capacity. Recently, cancer stem cells have been…”
Get full text

Glioblastoma cancer stem cell properties and synthetic biomaterials by Barcus, Craig E

“…Cancer stem cells serve as the initiating cells of some tumors, with self-renewing and differentiation capacity. Recently, cancer stem cells have been…”
Get full text