Search Results - "Barciszewska, Miroslawa Z"

A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells by Barciszewska, Anna-Maria, Gurda, Dorota, Głodowicz, Paweł, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z

“…Temozolomide (TMZ) is an oral alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma (GBM). Despite that high TMZ…”
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Mature miRNAs form secondary structure, which suggests their function beyond RISC by Belter, Agnieszka, Gudanis, Dorota, Rolle, Katarzyna, Piwecka, Monika, Gdaniec, Zofia, Naskręt-Barciszewska, Mirosława Z, Barciszewski, Jan

“…The generally accepted model of the miRNA-guided RNA down-regulation suggests that mature miRNA targets mRNA in a nucleotide sequence-specific manner. However,…”
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Comprehensive analysis of microRNA expression profile in malignant glioma tissues by Piwecka, Monika, Rolle, Katarzyna, Belter, Agnieszka, Barciszewska, Anna Maria, Żywicki, Marek, Michalak, Marcin, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z., Barciszewski, Jan

“…Malignant gliomas represent the most devastating group of brain tumors in adults, among which glioblastoma multiforme (GBM) exhibits the highest malignancy…”
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Changes in genomic 5-methylcytosine level mirror the response of orthodox (Acer platanoides L.) and recalcitrant (Acer pseudoplatanus L.) seeds to severe desiccation by Plitta-Michalak, Beata P, Naskret-Barciszewska, Miroslawa Z, Kotlarski, Szymon, Tomaszewski, Dominik, Tylkowski, Tadeusz, Barciszewski, Jan, Chmielarz, Pawel, Michalak, Marcin

“…Poor storability of recalcitrant seeds is due to their inability to tolerate low moisture content. Understanding the processes underlying their recalcitrance…”
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Inhibition of miR-21 in glioma cells using catalytic nucleic acids by Belter, Agnieszka, Rolle, Katarzyna, Piwecka, Monika, Fedoruk-Wyszomirska, Agnieszka, Naskręt-Barciszewska, Mirosława Z., Barciszewski, Jan

“…Despite tremendous efforts worldwide, glioblastoma multiforme (GBM) remains a deadly disease for which no cure is available and prognosis is very bad…”
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Mechanistic Insights on Metformin and Arginine Implementation as Repurposed Drugs in Glioblastoma Treatment by Barciszewska, Anna-Maria, Belter, Agnieszka, Barciszewski, Jakub F, Gawrońska, Iwona, Giel-Pietraszuk, Małgorzata, Naskręt-Barciszewska, Mirosława Z

“…As the most common and aggressive primary malignant brain tumor, glioblastoma is still lacking a satisfactory curative approach. The standard management…”
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A new molecular mechanism of RNA circularization and the microRNA sponge formation by Belter, Agnieszka, Popenda, Mariusz, Sajek, Marcin, Woźniak, Tomasz, Naskręt-Barciszewska, Mirosława Z., Szachniuk, Marta, Jurga, Stefan, Barciszewski, Jan

“…A new mechanism of RNA circularization driven by specific binding of miRNAs is described. We identified the 71 CUUCC pentanucleotide motifs distributed…”
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Global changes in DNA methylation in seeds and seedlings of Pyrus communis after seed desiccation and storage by Michalak, Marcin, Barciszewska, Mirosława Z, Barciszewski, Jan, Plitta, Beata P, Chmielarz, Paweł

“…The effects of storage and deep desiccation on structural changes of DNA in orthodox seeds are poorly characterized. In this study we analyzed the…”
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Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line by Barciszewska, Anna-Maria, Belter, Agnieszka, Gawrońska, Iwona, Giel-Pietraszuk, Małgorzata, Naskręt-Barciszewska, Mirosława Z

“…Glioblastoma (GBM) is the most common and aggressive primary brain tumor and one of the human malignancies with the highest mortality. Standard approaches for…”
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tRNA--the golden standard in molecular biology by Barciszewska, Mirosława Z, Perrigue, Patrick M, Barciszewski, Jan

“…Transfer RNAs (tRNAs) represent a major class of RNA molecules. Their primary function is to help decode a messenger RNA (mRNA) sequence in order to synthesize…”
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The Sequence and Structure Determine the Function of Mature Human miRNAs by Rolle, Katarzyna, Piwecka, Monika, Belter, Agnieszka, Wawrzyniak, Dariusz, Jeleniewicz, Jaroslaw, Barciszewska, Miroslawa Z, Barciszewski, Jan

“…Micro RNAs (miRNAs) (19-25 nucleotides in length) belong to the group of non-coding RNAs are the most abundant group of posttranscriptional regulators in…”
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The degree of global DNA hypomethylation in peripheral blood correlates with that in matched tumor tissues in several neoplasia by Barciszewska, Anna-Maria, Nowak, Stanisław, Naskręt-Barciszewska, Mirosława Z

“…There are no good blood and serum biomarkers for detection, follow up, or prognosis of brain tumors. However, they are needed for more detailed tumor…”
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Cross-reactivity between histone demethylase inhibitor valproic acid and DNA methylation in glioblastoma cell lines by Barciszewska, Anna-Maria, Belter, Agnieszka, Gawrońska, Iwona, Giel-Pietraszuk, Małgorzata, Naskręt-Barciszewska, Mirosława Z.

“…Currently, valproic acid (VPA) is known as an inhibitor of histone deacetylase (epigenetic drug) and is used for the clinical treatment of epileptic events in…”
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Global methylation status of sperm DNA in carriers of chromosome structural aberrations by Olszewska, Marta, Barciszewska, Miroslawa, Fraczek, Monika, Huleyuk, Nataliya, Chernykh, Vyacheslav, Zastavna, Danuta, Barciszewski, Jan, Kurpisz, Maciej

“…Male infertility might be clearly associated with aberrant DNA methylation patterns in human spermatozoa. An association between oxidative stress and the…”
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Epigenetic Integrity of Orthodox Seeds Stored under Conventional and Cryogenic Conditions by Beata P. Plitta-Michalak, Mirosława Z. Naskręt-Barciszewska, Jan Barciszewski, Paweł Chmielarz, Marcin Michalak

“…The level of 5-methylcytosine (m5C) in DNA has been observed to change in plants in response to biotic and abiotic stress factors. Little information has been…”
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DNA methylation of Quercus robur L. plumules following cryo-pretreatment and cryopreservation by Plitta, Beata P, Michalak, Marcin, Naskręt-Barciszewska, Mirosława Z, Barciszewski, Jan, Chmielarz, Paweł

“…Pedunculate oak (Quercus robur) is an ecologically and economically important forest tree species which produces seeds that are classified as recalcitrant…”
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Effect of desiccation on the dynamics of genome-wide DNA methylation in orthodox seeds of Acer platanoides L by Plitta, Beata P., Michalak, Marcin, Bujarska-Borkowska, Barbara, Barciszewska, Mirosława Z., Barciszewski, Jan, Chmielarz, Paweł

“…5-methylcytosine, an abundant epigenetic mark, plays an important role in the regulation of plant growth and development, but there is little information about…”
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A new frontier for molecular medicine: Noncoding RNAs by Szymanski, Maciej, Barciszewska, Miroslawa Z., Erdmann, Volker A., Barciszewski, Jan

“…It is now becoming evident that the variety of noncoding RNA (ncRNA) molecules play important roles in many cellular processes and they are not just mere…”
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new and efficient method for inhibition of RNA viruses by DNA interference by Nowak, Monika, Wyszko, Eliza, Fedoruk-Wyszomirska, Agnieszka, Pospieszny, Henryk, Barciszewska, Mirosława Z, Barciszewski, Jan

“…We report here a new method for inhibition of RNA viruses induced by dsDNA. We demonstrated that both long dsDNA molecules and short interfering DNA with a…”
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Suppression of human brain tumor with interference RNA specific for tenascin-C by Zukiel, Ryszard, Nowak, Stanislaw, Wyszko, Eliza, Rolle, Katarzyna, Gawronska, Iwona, Barciszewska, Miroslawa Z., Barciszewski, Jan

“…Glioblastoma multiforme (GBM) accounts for approximately 12-15% of intracranial neoplasms. The GBM remains refractory to therapy because of tumor…”
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