Search Results - "Barceló, Carles"
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A likelihood ratio approach for identifying three-quarter siblings in genetic databases
Published in Heredity (01-03-2021)“…The detection of family relationships in genetic databases is of interest in various scientific disciplines such as genetic epidemiology, population and…”
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2
Graphics for relatedness research
Published in Molecular ecology resources (01-11-2017)“…Studies of relatedness have been crucial in molecular ecology over the last decades. Good evidence of this is the fact that studies of population structure,…”
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3
The peril of proportions: robust niche indices for categorical data
Published in Methods in ecology and evolution (01-02-2017)“…Summary Indices of niche breadth and niche overlap for categorical data are typically expressed in terms of proportions of resources use. These are unit‐sum…”
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Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
Published in Nature genetics (01-04-2015)“…Eduard Batlle and colleagues find that poor-outcome subgroups of colorectal cancer are driven by genes expressed in tumor-associated stromal cells. They show…”
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Cumulative sum plots and retrospective parameters in first-trimester ductus venosus quality assurance
Published in Prenatal diagnosis (01-04-2013)“…ABSTRACT Objective This study aimed to evaluate the application of two quality assurance methods to the ductus venosus pulsatility index (DVPI), as a…”
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Clinical and Preclinical Targeting of Oncogenic Pathways in PDAC: Targeted Therapeutic Approaches for the Deadliest Cancer
Published in International journal of molecular sciences (01-03-2024)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death worldwide. It is commonly diagnosed in advanced stages and…”
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CaM interaction and Ser181 phosphorylation as new K-Ras signaling modulators
Published in Small GTPases (01-03-2011)“…The small G-protein Ras was the first oncogene to be identified and has a very important contribution to human cancer development (20-23% prevalence). K-RasB,…”
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A Log-Ratio Biplot Approach for Exploring Genetic Relatedness Based on Identity by State
Published in Frontiers in genetics (24-04-2019)“…The detection of cryptic relatedness in large population-based cohorts is of great importance in genome research. The usual approach for detecting closely…”
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The Role of LSD1 and LSD2 in Cancers of the Gastrointestinal System: An Update
Published in Biomolecules (Basel, Switzerland) (17-03-2022)“…Epigenetic mechanisms are known to play a key role in cancer progression. Specifically, histone methylation involves reversible post-translational modification…”
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10
The Mathematics of Compositional Analysis
Published in Österreichische Zeitschrift für Statistik (28-07-2016)“…The term compositional data analysis is historically associated to the approach based on the logratio transformations introduced in the eighties. Two main…”
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Biomarkers of axonal damage to favor early diagnosis in variant transthyretin amyloidosis (A-ATTRv)
Published in Scientific reports (05-01-2024)“…Early identification of ATTRv amyloidosis disease onset is still often delayed due to the lack of validated biomarkers of this disease. Light chain…”
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KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer
Published in Oncogene (23-09-2021)“…Oncogenic mutations of KRAS are found in the most aggressive human tumors, including colorectal cancer. It has been suggested that oncogenic KRAS…”
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Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth
Published in Cancer research (Chicago, Ill.) (15-02-2014)“…KRAS phosphorylation has been reported recently to modulate the activity of mutant KRAS protein in vitro. In this study, we defined S181 as a specific…”
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Usefulness of prebiopsy multifunctional and morphologic MRI combined with free-to-total prostate-specific antigen ratio in the detection of prostate cancer
Published in American journal of roentgenology (1976) (01-06-2011)“…The purpose of the study was to assess the predictive value for prostate cancer of MRI using morphologic (T2-weighted imaging [T2WI]) and functional (MR…”
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15
Challenges in precision medicine in pancreatic cancer: A focus in cancer stem cells and microbiota
Published in Frontiers in oncology (01-12-2022)“…Pancreatic cancer adenocarcinoma (PDAC) is a lethal disease, with the lowest 5-years survival rate of all cancers due to late diagnosis. Despite the advance…”
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Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells
Published in The EMBO journal (02-11-2022)“…Better understanding on interactions between SARS‐CoV‐2 and host cells should help to identify host factors that may be targetable to combat infection and…”
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Organoids: An Emerging Tool to Study Aging Signature across Human Tissues. Modeling Aging with Patient-Derived Organoids
Published in International journal of molecular sciences (29-09-2021)“…The biology of aging is focused on the identification of novel pathways that regulate the underlying processes of aging to develop interventions aimed at…”
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Ribonucleoprotein HNRNPA2B1 Interacts With and Regulates Oncogenic KRAS in Pancreatic Ductal Adenocarcinoma Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2014)“…Background & Aims Development of pancreatic ductal adenocarcinoma (PDAC) involves activation of c-Ki-ras2 Kirsten rat sarcoma oncogene homolog (KRAS)…”
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Therapeutic Potential of Mitotic Kinases’ Inhibitors in Cancers of the Gastrointestinal System
Published in Future pharmacology (01-09-2022)“…Mitosis entails mechanistic changes required for maintaining the genomic integrity in all dividing cells. The process is intricate and temporally and spatially…”
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Development of a Third Trimester Contingent Prognostic Prediction Scheme for Suspected Early-Onset Pre-Eclampsia
Published in Fetal diagnosis and therapy (01-09-2021)“…Short-term prediction of pre-eclampsia (PE) using soluble FMS-like tyrosine kinase-1 (sFlt-1)/ placental growth factor (PlGF) ratio has high false-positive…”
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