Search Results - "Barc, Celine"
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Inhaled bacteriophage therapy in a porcine model of pneumonia caused by Pseudomonas aeruginosa during mechanical ventilation
Published in British journal of pharmacology (01-09-2021)“…Background and Purpose 255 Pseudomonas aeruginosa is a main cause of ventilator‐associated pneumonia (VAP) with drug‐resistant bacteria. Bacteriophage therapy…”
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2
Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs
Published in Journal of controlled release (28-08-2019)“…DNA vaccination is an attractive technology, based on its well-established manufacturing process, safety profile, adaptability to rapidly combat pandemic…”
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3
Airway Administration of Flagellin Regulates the Inflammatory Response to Pseudomonas aeruginosa
Published in American journal of respiratory cell and molecular biology (01-10-2021)“…Excessive lung inflammation and airway epithelial damage are hallmarks of human inflammatory lung diseases, such as cystic fibrosis (CF). Enhancement of innate…”
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4
The Pig: A Relevant Model for Evaluating the Neutrophil Serine Protease Activities during Acute Pseudomonas aeruginosa Lung Infection
Published in PloS one (16-12-2016)“…The main features of lung infection and inflammation are a massive recruitment of neutrophils and the subsequent release of neutrophil serine proteases (NSPs)…”
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5
Schmallenberg virus experimental infection of sheep
Published in Veterinary microbiology (25-10-2013)“…Since late 2011, a novel orthobunyavirus, named Schmallenberg virus (SBV), has been implicated in many cases of severely malformed bovine and ovine offspring…”
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6
A DNA-Modified Live Vaccine Prime-Boost Strategy Broadens the T-Cell Response and Enhances the Antibody Response against the Porcine Reproductive and Respiratory Syndrome Virus
Published in Viruses (14-06-2019)“…The Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) induces reproductive disorders in sows and respiratory illnesses in growing pigs and is…”
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7
A DNA Prime Immuno-Potentiates a Modified Live Vaccine against the Porcine Reproductive and Respiratory Syndrome Virus but Does Not Improve Heterologous Protection
Published in Viruses (25-06-2019)“…The porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus inducing abortion in sows and respiratory disease in young pigs, is a leading…”
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8
Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets
Published in PloS one (23-11-2015)“…Cystic Fibrosis (CF) is the most prevalent autosomal recessive disease in the Caucasian population. A cystic fibrosis transmembrane conductance regulator…”
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9
Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets
Published in Pulmonary pharmacology & therapeutics (01-08-2019)“…Nebulization during mechanical ventilation is impeded by large extra-pulmonary drug deposition and long administration durations which currently limit…”
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10
A pig model of chronic hepatitis E displaying persistent viremia and a downregulation of innate immune responses in the liver
Published in Hepatology communications (01-11-2023)“…Hepatitis E virus (HEV) is a zoonotic virus transmitted by pig meat and responsible for chronic hepatitis E in immunocompromised patients. It has proved…”
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Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie: e1005077
Published in PLoS pathogens (01-08-2015)“…Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative diseases affecting a wide range of mammalian species. They are caused by…”
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12
Bovine spongiform encephalopathy agent in spleen from an ARR/ARR orally exposed sheep
Published in Journal of general virology (01-04-2006)“…1 UMR INRA ENVT 1225, Interactions Hôte-Agents Pathogènes, Ecole Nationale Vétérinaire de Toulouse, 23 Chemin des Capelles, 31076 Toulouse, France 2 CEA,…”
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13
Local immunization impacts the response of dairy cows to Escherichia coli mastitis
Published in Scientific reports (13-06-2017)“…Current vaccines to Escherichia coli mastitis have shown some albeit limited efficacy. Their mode of action has not been documented, and immune responses…”
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14
Immunogenicity and safety in rabbits of a Clostridioides difficile vaccine combining novel toxoids and a novel adjuvant
Published in Vaccine (07-03-2024)“…Clostridioides difficile infection (CDI) is a serious healthcare-associated disease, causing symptoms such as diarrhea and pseudomembranous colitis. The major…”
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15
Characterization of intestinal mononuclear phagocyte subsets in young ruminants at homeostasis and during Cryptosporidium parvum infection
Published in Frontiers in immunology (02-05-2024)“…Cryptosporidiosis is a poorly controlled zoonosis caused by an intestinal parasite, , with a high prevalence in livestock (cattle, sheep, and goats). Young…”
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Evidence of early increased sialylation of airway mucins and defective mucociliary clearance in CFTR-deficient piglets
Published in Journal of cystic fibrosis (01-01-2021)“…•CFTR-deficient pigs present increased lung mucin sialylation at birth in the absence of inflammation.•Increased mucin sialylation is linked to increased…”
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The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin
Published in Scientific reports (09-08-2017)“…XCR1 is selectively expressed on a conventional dendritic cell subset, the cDC1 subset, through phylogenetically distant species. The outcome of…”
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18
Establishment of a Newborn Lamb Gut-Loop Model to Evaluate New Methods of Enteric Disease Control and Reduce Experimental Animal Use
Published in Veterinary sciences (24-08-2021)“…Enteric infectious diseases are not all well controlled, which leads to animal suffering and sometimes death in the most severe cases, in addition to economic…”
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19
Transgenic Rabbits Expressing Ovine PrP Are Susceptible to Scrapie
Published in PLoS pathogens (01-08-2015)“…Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative diseases affecting a wide range of mammalian species. They are caused by…”
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20
Fetopathic effects of experimental Schmallenberg virus infection in pregnant goats
Published in Veterinary microbiology (01-11-2017)“…•Goats were inoculated with Schmallenberg virus at 28 and 42days of gestation.•Almost all of the fetuses were transplacentally infected.•Embryonic and fetal…”
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