Search Results - "Barbu, Ioana M"

Native Tandem and Ion Mobility Mass Spectrometry Highlight Structural and Modular Similarities in Clustered-Regularly-Interspaced Shot-Palindromic-Repeats (CRISPR)-associated Protein Complexes From Escherichia coli and Pseudomonas aeruginosa by van Duijn, Esther, Barbu, Ioana M., Barendregt, Arjan, Jore, Matthijs M., Wiedenheft, Blake, Lundgren, Magnus, Westra, Edze R., Brouns, Stan J.J., Doudna, Jennifer A., van der Oost, John, Heck, Albert J.R.

“…The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated genes) immune system of bacteria and archaea provides acquired…”
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Interrogating viral capsid assembly with ion mobility–mass spectrometry by Uetrecht, Charlotte, Barbu, Ioana M., Shoemaker, Glen K., van Duijn, Esther, Heck, Albert J. R.

“…Most proteins fulfil their function as part of large protein complexes. Surprisingly, little is known about the pathways and regulation of protein assembly…”
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The Metabolism of Lufotrelvir, a Prodrug Investigated for the Treatment of SARS-COV2 in Humans Following Intravenous Administration by Cheruvu, Narayan, van Duijn, Esther, Spigt, Pieter A., Barbu, Ioana M., Toussi, Sima S., Schildknegt, Klaas, Jones, Rhys M., Obach, R. Scott

“…The metabolism of lufotrelvir, a novel phosphate prodrug of PF-00835231 for the treatment of COVID-19, was evaluated in healthy human volunteers and clinical…”
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Assembly and Mechanical Properties of the Cargo-Free and Cargo-Loaded Bacterial Nanocompartment Encapsulin by Snijder, Joost, Kononova, Olga, Barbu, Ioana M, Uetrecht, Charlotte, Rurup, W. Frederik, Burnley, Rebecca J, Koay, Melissa S. T, Cornelissen, Jeroen J. L. M, Roos, Wouter H, Barsegov, Valeri, Wuite, Gijs J. L, Heck, Albert J. R

“…Prokaryotes mostly lack membranous compartments that are typical of eukaryotic cells, but instead, they have various protein-based organelles. These include…”
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On-the-fly targeted selection of labeled peptides in liquid chromatography/mass spectrometry based quantitative proteomics by Barbu, Ioana M. Taban, Smith, Donald F., van Breukelen, Bas, van der Burgt, Yuri E. M., Duursma, Marc C., Heck, Albert. J. R., Heeren, Ron M. A., Krijgsveld, Jeroen

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Development and application of criteria for classification of hydrolysed proteins in the framework of feed safety by van Raamsdonk, Leo W. D., Genouel, Christophe, Weiner, Anna, Prins, Theo W., Jardy, Nelly, Vonsovic, Stanislava, Barbu, Ioana M., Bescond, Marilyne, Paprocka, Ilona, Kwiatek, Krzysztof

“…In the view of a circular economy, there is an increasing need for (re-)using animal by-products that have a wide range of applications and sufficient safety…”
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Structure, stability and dynamics of norovirus P domain derived protein complexes studied by native mass spectrometry by Bereszczak, Jessica Z., Barbu, Ioana M., Tan, Ming, Xia, Ming, Jiang, Xi, van Duijn, Esther, Heck, Albert J.R.

“…Expression of the protruding (P) domain of the norovirus capsid protein, in vitro, results in the formation of P dimers and larger oligomers, 12-mer and 24-mer…”
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Erratum: Interrogating viral capsid assembly with ion mobility–mass spectrometry by Uetrecht, Charlotte, Barbu, Ioana M., Shoemaker, Glen K., van Duijn, Esther, Heck, Albert J. R.

“…Nature Chemistry 3, 126–132 (2011); published online 19 December 2010; corrected after print 23 July 2014. In the version of this Article originally published,…”
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Conformational Isomers of Calcineurin Follow Distinct Dissociation Pathways by Kükrer, Basak, Barbu, Ioana M., Copps, Jeffrey, Hogan, Patrick, Taylor, Susan S., van Duijn, Esther, Heck, Albert J. R.

“…In the gas-phase, ions of protein complexes typically follow an asymmetric dissociation pathway upon collisional activation, whereby an expelled small monomer…”
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Endogenous protein and peptide analysis with LC-MS/(MS): A feasibility study for authentication of raw-milk farmer's cheese by Barbu, Ioana M., Lamers, Robert-Jan A.N., Gerritsen, Henk W., Blokland, Marco H., Bremer, Monique G.E.G., Alewijn, Martin

“…When consumers buy Dutch ‘Boerenkaas’ (farmer's cheese), a cheese made from raw milk protected under the European traditional specialties guaranteed (TSG)…”
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THE METABOLISM OF LUFOTRELVIR, A PRODRUG INVESTIGATED FOR THE TREATMENT OF SARS-COV-2, IN HUMANS FOLLOWING INTRAVENOUS ADMINISTRATION by Cheruvu, Narayan, van Duijn, Esther, Spigt, Pieter A, Barbu, Ioana M, Toussi, Sima S, Schildknegt, Klaas, Jones, Rhys M, Obach, R Scott

“…The metabolism of lufotrelvir, a novel phosphate prodrug of PF-00835231 for the treatment of COVID-19, was evaluated in healthy human volunteers and clinical…”
Get full text