Search Results - "Barboza, Bianca"
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Jarid2 is induced by TCR signalling and controls iNKT cell maturation
Published in Nature communications (08-08-2014)“…Jarid2 is a reported component of three lysine methyltransferase complexes, polycomb repressive complex 2 (PRC2) that methylates histone 3 lysine 27 (H3K27),…”
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2
The role of interferon-γ on immune and allergic responses
Published in Memórias do Instituto Oswaldo Cruz (01-03-2005)“…Allergic diseases have been closely related to Th2 immune responses, which are characterized by high levels of interleukin (IL) IL-4, IL-5, IL-9 and IL-13…”
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3
Synthesis, bioevaluation and structural study of substituted phthalazin-1(2H)-ones acting as antifungal agents
Published in Molecules (Basel, Switzerland) (18-03-2013)“…Twenty-five polysubstituted phthalazinone derivatives were synthesized and tested for their antifungal activity against a panel of pathogenic and clinically…”
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4
IFN-gamma production by CD8+ T cells depends on NFAT1 transcription factor and regulates Th differentiation
Published in The Journal of immunology (1950) (01-11-2005)“…CD8+ T lymphocytes are excellent sources of IFN-gamma; however, the molecular mechanisms that dictate IFN-gamma expression upon TCR stimulation in these cells…”
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5
NFAT1 transcription factor in dendritic cells is required to modulate T helper cell differentiation
Published in Immunobiology (1979) (01-09-2014)“…Abstract The NFAT family of transcription factors plays a central role in the regulation of cytokine gene expression during the immune response. NFAT functions…”
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6
Anti-HIV activity of stilbene-related heterocyclic compounds
Published in Bioorganic & medicinal chemistry letters (01-08-2006)“…The inhibitory activity of several benzalphthalides, phthalazin-1-ones, imidazo[2,1- a]isoindoles and pyrimido[2,1- a]isoindoles on NF-κB, Tat and HIV…”
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7
IgY Antibodies from Birds: A Review on Affinity and Avidity
Published in Animals (Basel) (01-10-2023)“…IgY antibodies are found in the blood and yolk of eggs. Several studies show the feasibility of utilising IgY for immunotherapy and immunodiagnosis. These…”
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8
Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells
Published in Immunity (Cambridge, Mass.) (22-04-2011)“…The transcription factor FOXP3 is essential for the suppressive function of regulatory T cells that are required for maintaining self-tolerance. We have solved…”
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Potent, selective and reversible hMAO-B inhibition by benzalphthalides: Synthesis, enzymatic and cellular evaluations and virtual docking and predictive studies
Published in Bioorganic chemistry (01-05-2024)“…[Display omitted] •11 BPHs inhibited hMAO-B selectively with a Selectivity Indexes (SI) ≥ 100.•1 BPH inhibited hMAO-B selectively at the sub-nanomolar level.•2…”
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10
Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells
Published in Immunity (Cambridge, Mass.) (22-04-2011)Get full text
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11
Vasorelaxant activity of phthalazinones and related compounds
Published in Bioorganic & medicinal chemistry letters (15-05-2006)“…The vasorelaxant activity of some dihydrostilbenamides, imidazo[2,1-a]isoindoles, pyrimido[2,1-a]isoindoles and phthalazinones has been evaluated. Three…”
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12
Antimalarial activity of imidazo[2,1-a]isoindol-5-ol derivatives and related compounds
Published in European journal of medicinal chemistry (01-11-2011)“…The synthesis of several series of imidazo[2,1-a]isoindol-5-ol derivatives and the results of their evaluation against Plasmodium falciparum are presented and…”
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13
IFN- gamma Production by CD8 super(+) T Cells Depends on NFAT1 Transcription Factor and Regulates Th Differentiation
Published in The Journal of immunology (1950) (01-11-2005)“…CD8 super(+) T lymphocytes are excellent sources of IFN- gamma ; however, the molecular mechanisms that dictate IFN- gamma expression upon TCR stimulation in…”
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14
IFN-{gamma} Production by CD8+ T Cells Depends on NFAT1 Transcription Factor and Regulates Th Differentiation
Published in The Journal of immunology (1950) (01-11-2005)Get full text
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