Search Results - "Barbour, Suzanne E."

Apoptosis induces expression of sphingosine kinase 1 to release sphingosine‐1‐phosphate as a “come‐and‐get‐me” signal by Gude, David R., Alvarez, Sergio E., Paugh, Steven W., Mitra, Poulami, Yu, JiaDe, Griffiths, Rachael, Barbour, Suzanne E., Milstien, Sheldon, Spiegel, Sarah

“…ABSTRACT Sphingosine‐1‐phosphate (S1P) is a bioactive lipid that regulates myriad important cellular processes, including growth, survival, cytoskeleton…”
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Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA2β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes by Ali, Tomader, Lei, Xiaoyong, Barbour, Suzanne E., Koizumi, Akio, Chalfant, Charles E., Ramanadham, Sasanka

“…Type 1 diabetes (T1D) development, in part, is due to ER stress-induced β-cell apoptosis. Activation of the Ca2+-independent phospholipase A2 beta (iPLA2β)…”
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The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors by Payne, Shawn G., Oskeritzian, Carole A., Griffiths, Rachael, Subramanian, Preeti, Barbour, Suzanne E., Chalfant, Charles E., Milstien, Sheldon, Spiegel, Sarah

“…FTY720 is a potent immunomodulator drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. FTY720 is phosphorylated in vivo by…”
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The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2 by Paugh, Steven W., Payne, Shawn G., Barbour, Suzanne E., Milstien, Sheldon, Spiegel, Sarah

“…The potent immunosuppressive drug FTY720, a sphingosine analog, induces redistribution of lymphocytes from circulation to secondary lymphoid tissues. FTY720 is…”
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Macrophage polarization is linked to Ca2+-independent phospholipase A2β-derived lipids and cross-cell signaling in mice[S] by Nelson, Alexander J., Stephenson, Daniel J., Cardona, Christopher L., Lei, Xiaoyong, Almutairi, Abdulaziz, White, Tayleur D., Tusing, Ying G., Park, Margaret A., Barbour, Suzanne E., Chalfant, Charles E., Ramanadham, Sasanka

“…Phospholipases A2 (PLA2s) catalyze hydrolysis of the sn-2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can…”
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Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells by Song, Yuanda, Wilkins, Palmer, Hu, Wenhui, Murthy, Karnam S, Chen, Jing, Lee, Zendra, Oyesanya, Regina, Wu, Jinhua, Barbour, Suzanne E, Fang, Xianjun

“…PLA2 (phospholipase A2) enzymes play critical roles in membrane phospholipid homoeostasis and in generation of lysophospholipid growth factors. In the present…”
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Cytokines and inflammatory factors regulating immunoglobulin production in aggressive periodontitis by Schenkein, Harvey A., Barbour, Suzanne E., Tew, John G.

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Spontaneous Development of Endoplasmic Reticulum Stress That Can Lead to Diabetes Mellitus Is Associated with Higher Calcium-independent Phospholipase A2 Expression by Lei, Xiaoyong, Zhang, Sheng, Barbour, Suzanne E., Bohrer, Alan, Ford, Eric L., Koizumi, Akio, Papa, Feroz R., Ramanadham, Sasanka

“…Our recent studies indicate that endoplasmic reticulum (ER) stress causes INS-1 cell apoptosis by a Ca2+-independent phospholipase A2 (iPLA2β)-mediated…”
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Regulation of phosphatidylcholine homeostasis by calcium-independent phospholipase A2 by Barbour, Suzanne E, Kapur, Anita, Deal, Clifford L

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Role of calcium-independent phospholipase A(2)β in human pancreatic islet β-cell apoptosis by Lei, Xiaoyong, Zhang, Sheng, Bohrer, Alan, Barbour, Suzanne E, Ramanadham, Sasanka

“…Death of β-cells due to apoptosis is an important contributor to β-cell dysfunction in both type 1 and type 2 diabetes mellitus. Previously, we described…”
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Altered lipoprotein subclass distribution and PAF-AH activity in subjects with generalized aggressive periodontitis by Rufail, Miguel L, Schenkein, Harvey A, Barbour, Suzanne E, Tew, John G, van Antwerpen, Rik

“…In this study, we examined whether the documented increase of plasma triglycerides in patients with generalized aggressive periodontitis (GAgP) is associated…”
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Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5′-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells by Barbour, Suzanne E., Nguyen, Phuong T., Park, Margaret, Emani, Bhargavi, Lei, Xiaoyong, Kambalapalli, Mamatha, Shultz, Jacqueline C., Wijesinghe, Dayanjan, Chalfant, Charles E., Ramanadham, Sasanka

“…Diabetes is a consequence of reduced β-cell function and mass, due to β-cell apoptosis. Endoplasmic reticulum (ER) stress is induced during β-cell apoptosis…”
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Cell Cycle Dependence of Group VIA Calcium-independent Phospholipase A2 Activity by Manguikian, Alex D., Barbour, Suzanne E.

“…Homeostasis of phosphatidylcholine (PC) is regulated by the opposing actions between CTP:phosphocholine cytidylyltransferase (CT) and the group VIA…”
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Phosphatidylcholine Transfer Protein Promotes Apolipoprotein A-I-mediated Lipid Efflux in Chinese Hamster Ovary Cells by Baez, Juan M., Barbour, Suzanne E., Cohen, David E.

“…Phosphatidylcholine transfer protein (PC-TP) is a cytosolic protein of unknown function that catalyzes intermembrane transfer of phosphatidylcholines in vitro…”
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Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1 by Lei, Xiaoyong, Zhang, Sheng, Barbour, Suzanne E, Bohrer, Alan, Ford, Eric L, Koizumi, Akio, Papa, Feroz R, Ramanadham, Sasanka

“…Our recent studies indicate that endoplasmic reticulum (ER) stress causes INS-1 cell apoptosis by a Ca(2+)-independent phospholipase A(2)…”
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Delineation of the role of platelet-activating factor in the immunoglobulin G2 antibody response by Al-Darmaki, Salma, Knightshead, Kandi, Ishihara, Yuichi, Best, Al, Schenkein, Harvey A, Tew, John G, Barbour, Suzanne E

“…Localized aggressive periodontitis (LAgP) is a chronic inflammatory disease characterized by severe destruction of periodontal tissues surrounding the first…”
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Monocyte Differentiation in Localized Juvenile Periodontitis Is Skewed toward the Dendritic Cell Phenotype by BARBOUR, Suzanne E, ISHIHARA, Yuichi, FAKHER, Mohammed, AL-DARMAKI, Salma, CAVEN, Timothy H, SHELBURNE, C. P, BEST, Al M, SCHENKEIN, Harvey A, TEW, John G

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death by Lei, Xiaoyong, Barbour, Suzanne E, Ramanadham, Sasanka

“…Activation of phospholipases A(2) (PLA(2)s) leads to the generation of biologically active lipid mediators that can affect numerous cellular events. The Group…”
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Calcium-independent phospholipase A2 participates in KCl-induced calcium sensitization of vascular smooth muscle by Ratz, Paul H, Miner, Amy S, Barbour, Suzanne E

“…Abstract In vascular smooth muscle, KCl not only elevates intracellular free Ca2+ ([Ca2+ ]i ), myosin light chain kinase activity and tension ( T ), but also…”
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Regulation of group VIA phospholipase A2 expression by sterol availability by Seashols, Sarah J., del Castillo Olivares, Antonio, Gil, Gregorio, Barbour, Suzanne E.

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