Search Results - "Barbosa de Melo, Mônica"

Transcriptomics and network analysis highlight potential pathways in the pathogenesis of pterygium by de Guimarães, Juliana Albano, Hounpke, Bidossessi Wilfried, Duarte, Bruna, Boso, Ana Luiza Mylla, Viturino, Marina Gonçalves Monteiro, de Carvalho Baptista, Letícia, de Melo, Mônica Barbosa, Alves, Monica

“…Pterygium is a common ocular surface condition frequently associated with irritative symptoms. The precise identity of its critical triggers as well as the…”
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Demographic history differences between Hispanics and Brazilians imprint haplotype features by da Cruz, Pedro Rodrigues Sousa, Ananina, Galina, Secolin, Rodrigo, Gil-da-Silva-Lopes, Vera Lúcia, Lima, Carmen Silvia Passos, de França, Paulo Henrique Condeixa, Donatti, Amanda, Lourenço, Gustavo Jacob, de Araujo, Tânia Kawasaki, Simioni, Milena, Lopes-Cendes, Iscia, Costa, Fernando Ferreira, de Melo, Mônica Barbosa

“…Admixture is known to greatly impact the genetic landscape of a population and, while genetic variation underlying human phenotypes has been shown to differ…”
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The molecular mechanism responsible for HbSC retinopathy may depend on the action of the angiogenesis-related genes ROBO1 and SLC38A5 by da Silva Costa, Sueli Matilde, Ito, Mirta Tomie, da Cruz, Pedro Rodrigues Sousa, De Souza, Bruno Batista, Rios, Vinicius Mandolesi, Bertozzo, Victor de Haidar E, Camargo, Ana Carolina Lima, Viturino, Marina Gonçalves Monteiro, Lanaro, Carolina, de Albuquerque, Dulcinéia Martins, do Canto, Amanda Morato, Saad, Sara Teresinha Olalla, Ospina-Prieto, Stephanie, Ozelo, Margareth Castro, Costa, Fernando Ferreira, de Melo, Mônica Barbosa

“…HbSC disease, a less severe form of sickle cell disease, affects the retina more frequently and patients have higher rates of proliferative retinopathy that…”
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Comparative transcriptome analysis of endothelial progenitor cells of HbSS patients with and without proliferative retinopathy by Bertozzo, Victor de Haidar e, da Silva Costa, Sueli Matilde, Ito, Mirta Tomie, Cruz, Pedro Rodrigues Sousa da, Souza, Bruno Batista, Rios, Vinicius Mandolesi, Viturino, Marina Gonçalves Monteiro, Castro, Júlia Nicoliello Pereira de, Rodrigues, Thiago Adalton Rosa, Lanaro, Carolina, Albuquerque, Dulcinéia Martins de, Saez, Roberta Casagrande, Olalla Saad, Sara Teresinha, Ozelo, Margareth Castro, Costa, Fernando Ferreira, Melo, Mônica Barbosa de

“…Among sickle cell anemia (SCA) complications, proliferative sickle cell retinopathy (PSCR) is one of the most important, being responsible for visual…”
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Mechanisms and biomarker candidates in pterygium development by Wanzeler, Ana Cláudia Viana, Barbosa, Italo Antunes França, Duarte, Bruna, Borges, Daniel, Barbosa, Eduardo Buzolin, Kamiji, Danielle, Huarachi, Delma Regina Gomes, Melo, Mônica Barbosa de, Alves, Mônica

“…Pterygium pathogenesis has been mainly asso ciated with UV light exposure; however, this association remains quite controversial. The complete mechanism of…”
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Genetic comparison of sickle cell anaemia cohorts from Brazil and the United States reveals high levels of divergence by Cruz, Pedro R. S., Ananina, Galina, Gil-da-Silva-Lopes, Vera Lucia, Simioni, Milena, Menaa, Farid, Bezerra, Marcos A. C., Domingos, Igor F., Araújo, Aderson S., Pellegrino, Renata, Hakonarson, Hakon, Costa, Fernando F., de Melo, Mônica Barbosa

“…Genetic analysis of admixed populations raises special concerns with regard to study design and data processing, particularly to avoid population…”
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Association of LOC387715/ARMS2 (rs10490924) Gene Polymorphism with Age-Related Macular Degeneration in the Brazilian Population by Hirata, Fabio Endo, de Vasconcellos, José Paulo Cabral, Medina, Flávio MacCord, Rim, Priscila Hae Hyun, Fulco, Enzo Augusto Medeiros, de Melo, Mônica Barbosa

“…An association between LOC387715/ARMS2 (rs10490924) gene polymorphism and AMD has been reported. The aim of this study was to evaluate whether this…”
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Epigenetic analysis in placentas from sickle cell disease patients reveals a hypermethylation profile by Gil, Gislene Pereira, Ananina, Galina, Maschietto, Mariana, Lima, Sheila Coelho Soares, da Silva Costa, Sueli Matilde, Baptista, Leticia de Carvalho, Ito, Mirta Tomie, Costa, Fernando Ferreira, Costa, Maria Laura, de Melo, Mônica Barbosa

“…Pregnancy in Sickle Cell Disease (SCD) women is associated to increased risk of clinical and obstetrical complications. Placentas from SCD pregnancies can…”
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Placental transcriptome profile of women with sickle cell disease reveals differentially expressed genes involved in migration, trophoblast differentiation and inflammation by Baptista, Letícia Carvalho, Costa, Maria Laura, Surita, Fernanda Garanhani, Rocha, Cristiane de Souza, Lopes-Cendes, Iscia, Souza, Bruno Batista de, Costa, Fernando Ferreira, Melo, Mônica Barbosa de

“…Sickle cell disease (SCD) is a group of disorders whose common characteristic is the presence of hemoglobin (Hb) S in erythrocytes. The main consequence of…”
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Lack of Association Between Optineurin Gene Variants T34T, E50K, M98K, 691_692insAG and R545Q and Primary Open Angle Glaucoma in Brazilian Patients by Caixeta-Umbelino, Cristiano, de Vasconcellos, José Paulo Cabral, Costa, Vital Paulino, Kasahara, Niro, Paolera, Maurício Della, de Almeida, Geraldo Vicente, Cohen, Ralph, Mandia, Carmo, Rocha, Mylene Neves, Richeti, Flávio, Longui, Carlos Alberto, de Melo, Mônica Barbosa

“…Purpose: To verify the frequencies of T34T, E50K, M98K, 691_692insAG, and R545Q variants in the optineurin (OPTN) gene in Brazilian subjects with primary…”
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Highlight article: Whole-exome sequencing indicates FLG2 variant associated with leg ulcers in Brazilian sickle cell anemia patients by de Carvalho-Siqueira, Gabriela Queila, Ananina, Galina, de Souza, Bruno Batista, Borges, Murilo Guimarães, Ito, Mirta Tomie, da Silva-Costa, Sueli Matilde, de Farias Domingos, Igor, Falcão, Diego Arruda, Lopes-Cendes, Iscia, Bezerra, Marcos André Cavalcanti, da Silva Araújo, Aderson, Lucena-Araújo, Antônio Roberto, de Souza Gonçalves, Marilda, Saad, Sara Teresinha Olalla, Costa, Fernando Ferreira, de Melo, Mônica Barbosa

“…Although sickle cell anemia results from homozygosity for a single mutation at position 7 of the β-globin chain, the clinical aspects of this condition are…”
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Estimating the age of the p.Cys433Arg variant in the MYOC gene in patients with primary open-angle glaucoma by Marques, Ana Maria, Ananina, Galina, Costa, Vital Paulino, de Vasconcellos, José Paulo Cabral, de Melo, Mônica Barbosa

“…The aim of this study was to estimate the age of the Cys433Arg (c.1297T>C, p.Cys433Arg) variant by comparing the genotypes of individuals affected and not…”
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Abnormal expression of inflammatory genes in placentas of women with sickle cell anemia and sickle hemoglobin C disease by Baptista, Letícia C., Costa, Maria Laura, Ferreira, Regiane, Albuquerque, Dulcinéia M., Lanaro, Carolina, Fertrin, Kleber Y., Surita, Fernanda G., Parpinelli, Mary A., Costa, Fernando F., Melo, Mônica Barbosa de

“…Sickle cell disease (SCD) is a complex disease that is characterized by the polymerization of deoxyhemoglobin S, altered red blood cell membrane biology,…”
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Genotype-Phenotype Correlations in CYP1B1-Associated Primary Congenital Glaucoma Patients Representing Two Large Cohorts from India and Brazil by de Melo, Mônica Barbosa, Mandal, Anil K, Tavares, Ivan M, Ali, Mohammed Hasnat, Kabra, Meha, de Vasconcellos, José Paulo Cabral, Senthil, Sirisha, Sallum, Juliana M F, Kaur, Inderjeet, Betinjane, Alberto J, Moura, Christiane R, Paula, Jayter S, Costa, Karita A, Sarfarazi, Mansoor, Paolera, Mauricio Della, Finzi, Simone, Ferraz, Victor E F, Costa, Vital P, Belfort, Jr, Rubens, Chakrabarti, Subhabrata

“…Primary congenital glaucoma (PCG), occurs due to the developmental defects in the trabecular meshwork and anterior chamber angle in children. PCG exhibits…”
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Investigation of CAV1/CAV2 rs4236601 and CDKN2B-AS1 rs2157719 in primary open-angle glaucoma patients from Brazil by Nunes, Hugo Freire, Ananina, Galina, Costa, Vital Paulino, Zanchin, Nilson Ivo Tonin, de Vasconcellos, José Paulo Cabral, de Melo, Mônica Barbosa

“…Large-scale genome-wide association studies have identified several susceptibility variants associated with the risk of primary open-angle glaucoma (POAG),…”
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Mutation analysis of CRYAA, CRYGC, and CRYGD associated with autosomal dominant congenital cataract in Brazilian families by Santana, Alessandro, Waiswol, Mauro, Arcieri, Enyr Saran, Cabral de Vasconcellos, José Paulo, Barbosa de Melo, Mônica

“…Congenital cataracts are one of the most treatable causes of visual impairment and blindness during infancy. Approximately 50% of all congenital cataract cases…”
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Keeping an eye on myocilin: a complex molecule associated with primary open-angle glaucoma susceptibility by Menaa, Farid, Braghini, Carolina Ayumi, Vasconcellos, Jose Paulo Cabral De, Menaa, Bouzid, Costa, Vital Paulino, Figueiredo, Eugênio Santana De, Melo, Monica Barbosa De

“…MYOC encodes a secretary glycoprotein of 504 amino acids named myocilin. MYOC is the first gene to be linked to juvenile open-angle glaucoma (JOAG) and some…”
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Structural Assessment of PITX2, FOXC1, CYP1B1, and GJA1 Genes in Patients with Axenfeld-Rieger Syndrome with Developmental Glaucoma by Cella, Wener, Cabral de Vasconcellos, Jose Paulo, Barbosa de Melo, Monica, Kneipp, Bianca, Costa, Fernando Ferreira, Longui, Carlos Alberto, Costa, Vital Paulino

“…Axenfeld-Rieger (AR) is an autosomal dominant disorder with phenotypic heterogeneity characterized by anterior segment dysgenesis, facial bone defects, and…”
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Comparative transcriptomic analysis of circulating endothelial cells in sickle cell stroke by de Castro, Júlia Nicoliello Pereira, da Silva Costa, Sueli Matilde, Camargo, Ana Carolina Lima, Ito, Mirta Tomie, de Souza, Bruno Batista, de Haidar e Bertozzo, Victor, Rodrigues, Thiago Adalton Rosa, Lanaro, Carolina, de Albuquerque, Dulcinéia Martins, Saez, Roberta Casagrande, Saad, Sara Teresinha Olalla, Ozelo, Margareth Castro, Cendes, Fernando, Costa, Fernando Ferreira, de Melo, Mônica Barbosa

“…Ischemic stroke (IS) is one of the most impairing complications of sickle cell anemia (SCA), responsible for 20% of mortality in patients. Rheological…”
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Association of ABCA1 (rs2472493) and GAS7 (rs9913911) gene variants with primary open-angle glaucoma in a Brazilian population by Araki, Manoel Vinicius Rocha, Silva, Yuri Carvalho Oiamore, Rodrigues, Thiago Adalton Rosa, Bajano, Flavia Fialho, de Souza, Bruno Batista, Costa, Fernando Ferreira, Costa, Vital Paulino, de Melo, Mônica Barbosa, de Vasconcellos, José Paulo Cabral

“…Glaucoma is the world's leading cause of irreversible blindness, with primary open-angle glaucoma (POAG) being the most prevalent subtype. In recent years,…”
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