Search Results - "Barbosa‐Filho, José M."

Docking Studies for Multi-Target Drugs by Scotti, Luciana, Mendonca Junior, Francisco J B, Ishiki, Hamilton M, Ribeiro, Frederico F, Singla, Rajeev K, Barbosa Filho, Jose M, Da Silva, Marcelo S, Scotti, Marcus T

“…The most basic principle of drug action is found in the lock and key model, where the highest possible affinity for a target that also avoids side effects is…”
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Biological and physical approaches on the role of piplartine (piperlongumine) in cancer by Henrique, Tiago, Zanon, Caroline de F., Girol, Ana P., Stefanini, Ana Carolina Buzzo, Contessoto, Nayara S. de A., da Silveira, Nelson J. F., Bezerra, Daniel P., Silveira, Edilberto R., Barbosa-Filho, José M., Cornélio, Marinonio L., Oliani, Sonia M., Tajara, Eloiza H.

“…Chronic inflammation provides a favorable microenvironment for tumorigenesis, which opens opportunities for targeting cancer development and progression…”
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Subchronic administration of riparin III induces antidepressive-like effects and increases BDNF levels in the mouse hippocampus by Vasconcelos, Auriana S., Oliveira, Iris C.M., Vidal, Laura T.M., Rodrigues, Gabriel C., Gutierrez, Stanley J.C., Barbosa-Filho, José M., Vasconcelos, Silvânia M.M., de França Fonteles, Marta M., Gaspar, Danielle M., de Sousa, Francisca C.F.

“…Riparin III (Rip III) is an alcamide isolated from Aniba riparia that has presented effects of antidepressant and anxiolytic activities in acute stress…”
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Evaluation of the cytotoxic and antitumour effects of the essential oil from Mentha x villosa and its main compound, rotundifolone by Amaral, Ricardo G., Fonseca, Cecília S., Silva, Tayane Kayne M., Andrade, Luciana N., França, Maria E., Barbosa-Filho, José M., de Sousa, Damião P., Moraes, Manoel O., Pessoa, Cláudia Ó, Carvalho, Adriana A., Thomazzi, Sara Maria

“…Objectives The aim of this study was to investigate the cytotoxic and antitumour effects of the essential oil from the leaves of Mentha x villosa (EOMV) and…”
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3,6-Dimethoxy-6″,6″-Dimethyl-(7,8,2″,3″)-Chromeneflavone, a Flavonoid Isolated from Lonchocarpus Araripensis Benth. (Fabaceae), Reduces Nociceptive Behaviour in Mice by Almeida, Jackson R. G. S., Silva, Juliane C., Guimarães, Amanda L., Oliveira, Ana P., Souza, Grasielly R., Oliveira-Júnior, Raimundo G., Lima-Saraiva, Sarah R. G., Barbosa-Filho, José M., Braz-Filho, Raimundo, Queiroz, Dinalva Brito, Botelho, Marco Antônio

“…Lonchocarpus araripensis Benth. is largely distributed in the northeast region of Brazil. It is popularly known as ‘sucupira’. Recent studies have shown that…”
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Warifteine, a bisbenzylisoquinoline alkaloid, induces relaxation by activating potassium channels in vascular myocytes by Assis, Ápio CL, Araújo, Islania GA, Lima, Renata PC, Almeida, Mônica M, Marinho, Alexsandro F, Barbosa-Filho, José M, Cruz, Jader S, Silva, Darizy F, Medeiros, Isac A

“…Summary The present study used functional and electrophysiological approaches to investigate the mechanisms by which warifteine, a bisbenzylisoquinoline…”
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Computer-Aided Drug Design Studies in Association with in vitro Antileishmanial Tests for New Chalcones by R. da Silva, Gleice, S. Santos, Francisnaira, F. Leite, Fernando, A. H. Acevedo, Chonny, F. de Sousa, Natália, B. Grimaldi, Gabriela, B. P. Soares, Milena, T. Guimarães, Elisalva, T. Scotti, Marcus, Cezar Rodrigues, Luis, J. B. Mendonça Júnior, Francisco, H. Campana, Eloísa, M. Barbosa Filho, José, I. F. Magalhães, Hemerson, Q. S. Guerra, Felipe

“…In silico and in vitro tests can reveal promising anti-leishmania activity for natural products and their derivatives. The aim of this study was to investigate…”
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Ortho-eugenol exhibits anti-nociceptive and anti-inflammatory activities by Fonsêca, Diogo V., Salgado, Paula R.R., Aragão Neto, Humberto de C., Golzio, Adriana M.F.O., Caldas Filho, Marcelo R.D., Melo, Cynthia G.F., Leite, Fagner C., Piuvezam, Marcia R., Pordeus, Liana Clébia de Morais, Barbosa Filho, José M., Almeida, Reinaldo N.

“…Ortho-eugenol is a much used phenylpropanoid whose ability to reduce pain and inflammation has never been studied. Researching ortho-eugenol's antinociceptive…”
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Tropane Alkaloids from Erythroxylum caatingae Plowman by de Oliveira, Steno L., Tavares, Josean F., Branco, Marianna V. S. Castello, Lucena, Hellane F. S., Barbosa-Filho, José M., de F. Agra, Maria, do Nascimento, Silene C., dos S. Aguiar, Jaciana, da Silva, Teresinha G., de Simone, Carlos A., de Araújo-Júnior, João X., da Silva, Marcelo S.

“…Three tropane alkaloids, 1–3, were isolated from Erythroxylum caatingae, i.e., 6β‐benzoyloxy‐3α‐[(4‐hydroxy‐3,5‐dimethoxybenzoyl)oxy]tropane (1), a new tropane…”
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Inactivation of Spoilage Yeasts by Mentha spicata L. and M . × villosa Huds. Essential Oils in Cashew, Guava, Mango, and Pineapple Juices by da Cruz Almeida, Erika T, de Medeiros Barbosa, Isabella, Tavares, Josean F, Barbosa-Filho, José M, Magnani, Marciane, de Souza, Evandro L

“…This study evaluated the efficacy of the essential oil from L. (MSEO) and . × Huds. (MVEO) to inactivate and in Sabouraud dextrose broth and cashew, guava,…”
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Synthesis, in silico Study and Antimicrobial Evaluation of New Selenoglycolicamides by Souza, Helivaldo, de Sousa, Roxana, Lira, Bruno, Vilela, Raquel, Borges, Nathalie, de Siqueira‑Junior, José, Lima, Edeltrudes, Jardim, Jeane, da Silva, Gracielle, Barbosa‑Filho, José, de Athayde‑Filho, Petrônio

“…Nine new compounds derived from selenoglycolic acid were synthesized, and their structures were fully characterized by elemental analysis, infrared (IR), 1H…”
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A chemical marker proposal for the Lantana genus: composition of the essential oils from the leaves of Lantana radula and L. canescens by Sena Filho, José G, Xavier, Haroudo S, Barbosa Filho, José M, Duringer, Jennifer M

“…Essential oil extracts from the leaves of two Lantana species (L. radula Sw. and L. canescens Kunth), for which no prior analysis has been reported, were…”
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Yangambin Cytotoxicity: A Pharmacologically Active Lignan Obtained from Ocotea duckei Vattimo (Lauraceae) by Monte Neto, Rubens L., Sousa, M. A., Dias, Celidarque S., Barbosa Filho, José M., Oliveira, Márcia R.

“…The in vitro cytotoxic potential of yangambin was evaluated. Yangambin is a pharmacologically active furofuran lignan obtained from the leaves of Ocotea…”
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A new coumarin derivative, 4-acetatecoumarin, with antifungal activity and association study against Aspergillus spp by Guerra, Felipe Q.S., Araújo, Rodrigo S.A., Sousa, Janiere P., Silva, Viviane A., Pereira, Fillipe O., Mendonça-Junior, Francisco J.B., Barbosa-Filho, José M., Pereira, Julio Abrantes, Lima, Edeltrudes O.

“…Fungal infections have become a concern for health professionals, and the emergence of resistant strains has been reported for all known classes of antifungal…”
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Neolignan Licarin A presents effect against Leishmania (Leishmania) major associated with immunomodulation in vitro by Néris, Patrícia L.N., Caldas, John P.A., Rodrigues, Yara K.S., Amorim, Francianne M., Leite, Jacqueline A., Rodrigues-Mascarenhas, Sandra, Barbosa-Filho, José M., Rodrigues, Luis C., Oliveira, Márcia R.

“…•Licarin A inhibits the proliferation of Leishmania (L.) major promastigotesin vitro.•This neolignan induces DNA fragmentation on L. (L.) major…”
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Mechanism for the uncoupling of oxidative phosphorylation by juliprosopine on rat brain mitochondria by Maioli, Marcos A., Lemos, Danilo E.C.V., Guelfi, Marieli, Medeiros, Hyllana C.D., Riet-Correa, Franklin, Medeiros, Rosane M.T., Barbosa-Filho, José M., Mingatto, Fábio E.

“…Prosopis juliflora, popularly known as Algaroba, is a major problem because the lack of food during the driest times of the year and its high palatability and…”
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Bioactivities from marine algae of the genus Gracilaria by de Almeida, Cynthia Layse F, Falcão, Heloina de S, Lima, Gedson R de M, Montenegro, Camila de A, Lira, Narlize S, de Athayde-Filho, Petrônio F, Rodrigues, Luis C, de Souza, Maria de Fátima V, Barbosa-Filho, José M, Batista, Leônia M

“…Seaweeds are an important source of bioactive metabolites for the pharmaceutical industry in drug development. Many of these compounds are used to treat…”
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Evaluation of naphthoquinones identified the acetylated isolapachol as a potent and selective antiplasmodium agent by Moreira, Diogo R M, de Sá, Matheus S, Macedo, Taís S, Menezes, Maria N, Reys, José Rui M, Santana, Antônio E G, Silva, Thaissa L, Maia, Gabriela L A, Barbosa-Filho, José M, Camara, Celso A, da Silva, Tania M S, da Silva, Katia N, Guimaraes, Elisalva T, dos Santos, Ricardo R, Goulart, Marília O F, Soares, Milena B P

“…This study reports on the design, synthesis and antiparasitic activity of three new semi-synthetic naphthoquinones structurally related to the…”
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Curine, a bisbenzylisoquinoline alkaloid, blocks L-type Ca2+ channels and decreases intracellular Ca2+ transients in A7r5 cells by Medeiros, Marcos A.A., Pinho, José F., De-Lira, Daysiane P., Barbosa-Filho, José M., Araújo, Demetrius A.M., Cortes, Steyner F., Lemos, Virgínia S., Cruz, Jader S.

“…Curine is a novel bisbenzylisoquinoline alkaloid that has previously been reported as a vasodilator. The underlying mechanism(s) of the vasodilator effect of…”
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Effects of umbelliferone in a murine model of allergic airway inflammation by Vasconcelos, Juliana F., Teixeira, Mauro M., Barbosa-Filho, José M., Agra, Maria F., Nunes, Xirley P., Giulietti, Ana Maria, Ribeiro-dos-Santos, Ricardo, Soares, Milena B.P.

“…The therapeutic effects of umbelliferone (30, 60 and 90 mg/kg), a coumarin isolated from Typha domingensis (Typhaceae) were investigated in a mouse model of…”
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