Search Results - "Barbosa, Flávio Augusto Rocha"

New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells by Bueno, Diones Caeran, Canto, Rômulo Faria Santos, de Souza, Viviane, Andreguetti, Rafaela Rafognatto, Barbosa, Flávio Augusto Rocha, Naime, Aline Aita, Dey, Partha Narayan, Wüllner, Verena, Lopes, Mark William, Braga, Antônio Luiz, Methner, Axel, Farina, Marcelo

“…Probucol, a hypocholesterolemic compound, is neuroprotective in several models of neurodegenerative diseases but has serious adverse effects in vivo. We now…”
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Novel Probucol Analogue, 4,4′-Diselanediylbis (2,6-Di-tert-Butylphenol), Prevents Oxidative Glutamate Neurotoxicity In Vitro and Confers Neuroprotection in a Rodent Model of Ischemic Stroke by Jacques, Mauricio Tavares, de Souza, Viviane, Barbosa, Flávio Augusto Rocha, Faria Santos Canto, Rômulo, Lopes, Samantha Cristiane, Prediger, Rui Daniel, Braga, Antônio Luiz, Aschner, Michael, Farina, Marcelo

“…Oxidative glutamate toxicity is regarded as one of the injurious mechanisms associated with ischemic stroke, which represents a major health problem and…”
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Dihydropyrimidinone-derived selenoesters efficacy and safety in an in vivo model of Aβ aggregation by Pereira, Flávia Suelen de Oliveira, Barbosa, Flavio Augusto Rocha, Canto, Rômulo Farias Santos, Lucchese, Cristiane, Pinton, Simone, Braga, Antônio Luiz, Azeredo, Juliano Braun de, Quines, Caroline Brandão, Ávila, Daiana Silva

“…Multi-target mechanisms of FA90 compound. APP= Amyloid Precursor Protein; sAPPβ= Soluble Amyloid Precursor Protein-β; Aβ= Amyloid-beta peptide;LAChrs=…”
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Prevention of ferroptosis in acute scenarios: an in vitro study with classic and novel anti-ferroptotic compounds by Naime, Aline Aita, Barbosa, Flavio Augusto Rocha, Bueno, Diones Caeran, Curi Pedrosa, Rozangela, Canto, Rômulo Faria Santos, Colle, Dirleise, Braga, Antônio Luiz, Farina, Marcelo

“…Ferroptosis, an iron-dependent form of cell death, has critical roles in diverse pathologies. Data on the temporal events mediating the prevention of…”
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Design, Synthesis, and In Vitro Evaluation of a Novel Probucol Derivative: Protective Activity in Neuronal Cells Through GPx Upregulation by Quispe, Ruth Liliám, Canto, Rômulo Faria Santos, Jaramillo, Michael Lorenz, Barbosa, Flavio Augusto Rocha, Braga, Antônio Luiz, de Bem, Andreza Fabro, Farina, Marcelo

“…Recent studies have shown that probucol (PB), a hipocholesterolemic agent with antioxidant and anti-inflammatory properties, presents neuroprotective…”
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Antiproliferative Effect and Autophagy Inhibition of Dihydropyrimidinone‐Cinnamic Acid Hybrids by Barbosa, Flavio Augusto Rocha, Rode, Michele Patrícia, Santos Canto, Rômulo Faria, Silva, Adny Henrique, Creczynski‐Pasa, Tânia Beatriz, Braga, Antonio Luiz

“…Here we report the design, synthesis and evaluation of dihydropyrimidinones (DHPMs)‐cinnamic acids hybrids as potential anti‐cancer compounds. The synthetic…”
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