Cutaneous toxoplasmosis in an immunosuppressed dog

Cutaneous toxoplasmosis in an immunosuppressed dog

A seven-year-old female spayed Schnauzer was presented with cutaneous ulcerated nodular lesions shortly after the beginning of an immunosuppressive treatment for immune-mediated hemolytic disease. Cytology was performed and a great number of neutrophils and banana-shaped organisms were observed. Bio...

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Bibliographic Details
Published in:Arquivo brasileiro de medicina veterinária e zootecnia Vol. 66; no. 3; pp. 797 - 800
Main Authors: Oliveira, T.S., Turchetti, A.P., Barbosa, F.B.S., Bicalho, A.L.F., Alencar, C.A.D., Paixão, T.A., Santos, R.L.
Format: Journal Article
Language:English
Published: Universidade Federal de Minas Gerais, Escola de Veterinária 01-06-2014
Universidade Federal de Minas Gerais
Subjects:
cão
imunossupressão
toxoplasmose cutânea
VETERINARY SCIENCES
cutaneous
toxoplasmosis
imunossupressão
immunosuppression
dog
cão
toxoplasmose cutânea
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Summary:A seven-year-old female spayed Schnauzer was presented with cutaneous ulcerated nodular lesions shortly after the beginning of an immunosuppressive treatment for immune-mediated hemolytic disease. Cytology was performed and a great number of neutrophils and banana-shaped organisms were observed. Biopsy showed a neutrophilic and histiocytic dermatitis and panniculitis with myriads of intralesional bradyzoites cysts and tachyzoites. PCR analysis was positive for Toxoplasma gondii and negative for Neospora caninum. Immunohistochemistry confirmed intralesional T. gondii antigens. This study reports a rare case of cutaneous toxoplasmosis in an immunosuppressed dog. Uma cadela Schnauzer, castrada, de sete anos apresentou lesões cutâneas nodulares ulceradas pouco tempo após início de tratamento imunossupressor para doença hemolítica imunomediada. Foi realizado exame citológico, e um grande número de neutrófilos e estruturas em forma de banana foi observado. Biópsia mostrou dermatite e paniculite neutrofílica e histiocítica com miríades de taquizoítos e cistos de bradizoítos intralesionais. PCR foi positivo para Toxoplasma gondii e negativo para Neospora caninum. Imuno-histoquímica confirmou antígenos de T. gondii intralesionais. Este trabalho relata um caso raro de toxoplasmose cutânea em um cão imunossuprimido.
ISSN:0102-0935
1678-4162
0102-0935
DOI:10.1590/1678-41626891