Search Results - "Barbosa, Euzebio Guimaraes"
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Compatibility study between ferulic acid and excipients used in cosmetic formulations by TG/DTG, DSC and FTIR
Published in Journal of thermal analysis and calorimetry (01-02-2017)“…Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is a phytochemical constituent from the polyphenols group commonly found in whole grains, spinach, parsley,…”
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Effect of hydroxypropyl methylcellulose on beta cyclodextrin complexation of praziquantel in solution and in solid state
Published in Journal of inclusion phenomena and macrocyclic chemistry (01-06-2016)“…The effect of hydroxypropyl methylcellulose (HPMC) on complexation of praziquantel with beta cyclodextrin (PRZ–βCD) in solution and in the solid state was…”
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3
2-Styryl-quinoline-4-carboxylic acids: Synthesis, characterization, and investigation of their optical properties and antimicrobial activity
Published in Dyes and pigments (01-10-2024)“…Styrylquinoline-based fluorophores 1–10 were synthesized via Knoevenagel and Pfitzinger reactions. The molecules were fully characterized and studied for the…”
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4
Capsaicin-like analogue induced selective apoptosis in A2058 melanoma cells: Design, synthesis and molecular modeling
Published in Bioorganic & medicinal chemistry (01-07-2019)“…[Display omitted] The use of molecules inspired by natural scaffolds has proven to be a very promising and efficient method of drug discovery. In this work,…”
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Intra-hemocoel injection of pseurotin A from Metarhizium anisopliae, induces dose-dependent reversible paralysis in the Greater Wax Moth (Galleria mellonella)
Published in Fungal genetics and biology (01-04-2022)“…•Pseurotin A was isolated from supernatant of Metarhizium anisopliae culture.•Pseurotin A can induce dose-dependent reversible paralysis in Galleria…”
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Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity
Published in Bioorganic chemistry (01-08-2020)“…[Display omitted] •Development of versatile one-pot synthesis for diaryl disulfides and diaryl thiosulfonates.•The thiosulfonates have demonstrated to be…”
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7
Methyl jasmonate induces selaginellin accumulation in Selaginella convoluta
Published in Metabolomics (21-12-2022)“…Introduction Selaginellins are specialized metabolites and chemotaxonomic markers for Selaginella species . Despite the growing interest in these compounds as…”
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Development, characterization, and in-vivo evaluation of a novel chitosan: Guar gum particulate system for colonic release of triamcinolone
Published in Journal of drug delivery science and technology (01-06-2024)“…Drug delivery systems based on carbohydrate polymers have shown promising results for the colonic release of drugs due to the selective degradation by the…”
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Erythroxylum pungens Tropane Alkaloids: GC-MS Analysis and the Bioactive Potential of 3-(2-methylbutyryloxy)tropan-6,7-diol in Zebrafish (Danio rerio)
Published in Planta medica (01-02-2021)“…Tropane alkaloids are specialized plant metabolites mostly found in the Erythroxylaceae and Solanaceae families. Although tropane alkaloids have a high degree…”
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Structural characterization of a novel peptide with antimicrobial activity from the venom gland of the scorpion Tityus stigmurus: Stigmurin
Published in Peptides (New York, N.Y. : 1980) (01-06-2015)“…•This work describes a novel peptide (Stigmurin) from Tityus stigmurus scorpion.•Stigmurin's structure was evaluated in silico and by circular dichroism.•The…”
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Isolation, spectral characterization, molecular docking, and cytotoxic activity of alkaloids from Erythroxylum pungens O. E. Shulz
Published in Phytochemistry (Oxford) (01-11-2018)“…Stem bark, root bark, and leaf extracts of Erythroxylum pungens were subjected to phytochemical analysis. N,N-dimethyltryptamine (DMT) was isolated and…”
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In Silico Study, Physicochemical, and In Vitro Lipase Inhibitory Activity of α , β -Amyrenone Inclusion Complexes with Cyclodextrins
Published in International journal of molecular sciences (13-09-2021)“…, -amyrenone (ABAME) is a triterpene derivative with many biological activities; however, its potential pharmacological use is hindered by its low solubility…”
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13
Planning new Trypanosoma cruzi CYP51 inhibitors using QSAR studies
Published in Molecular diversity (01-11-2021)“…Chagas disease kills over 10,000 people per year, and approximately 8 million people are infected by Trypanosoma cruzi . The reference drug for treatment of…”
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Exploiting the biological activities of a lipopeptide extract produced by Bacillus subtilis UFPEDA 438 in light of the SARS-CoV-2 pandemic
Published in Biocatalysis and agricultural biotechnology (01-06-2024)“…Lipopeptides are biosurfactants, substances with a high surfactant potential where each family corresponds to a group of isoforms that differs in the peptide's…”
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Activity of pyrrolizidine alkaloids against biofilm formation and Trichomonas vaginalis
Published in Biomedicine & pharmacotherapy (01-10-2016)“…Graphical abstract Our results point out the applicability of PAs for semi-synthesis as well as indicate these molecules as promising leads for further studies…”
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Compatibility study between atorvastatin and excipients using DSC and FTIR
Published in Journal of thermal analysis and calorimetry (01-02-2016)“…The aim of this study was to characterize atorvastatin and evaluate interactions between atorvastatin and various excipients by DSC and FTIR, using Pearson’s…”
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Characterization and Trypanocidal Activity of a Novel Pyranaphthoquinone
Published in Molecules (Basel, Switzerland) (30-09-2017)“…Chagas disease is an endemic parasitic infection that occurs in 21 Latin American countries. New therapies for this disease are urgently needed, as the only…”
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Inclusion Complexes of Copaiba (Copaifera multijuga Hayne) Oleoresin and Cyclodextrins: Physicochemical Characterization and Anti-Inflammatory Activity
Published in International journal of molecular sciences (18-11-2017)“…Complexation with cyclodextrins (CDs) is a technique that has been extensively used to increase the aqueous solubility of oils and improve their stability. In…”
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Host–guest interactions between benznidazole and beta-cyclodextrin in multicomponent complex systems involving hydrophilic polymers and triethanolamine in aqueous solution
Published in Journal of molecular liquids (01-10-2013)“…Association of hydrophilic compounds with cyclodextrins to increase drug solubility has been extensively studied in aqueous solution. However, the mechanism of…”
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Amorphous solid dispersions of hecogenin acetate using different polymers for enhancement of solubility and improvement of anti-hyperalgesic effect in neuropathic pain model in mice
Published in Biomedicine & pharmacotherapy (01-01-2018)“…[Display omitted] Hecogenin acetate (HA) is an acetylated sapogenin that has shown potential antihyperalgesic activity, inhibiting descending pain and acting…”
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