Search Results - "Barbosa, Daniel"

Molecular mechanisms of ferroptosis and their involvement in brain diseases by Costa, Inês, Barbosa, Daniel José, Benfeito, Sofia, Silva, Vera, Chavarria, Daniel, Borges, Fernanda, Remião, Fernando, Silva, Renata

“…Ferroptosis is a type of regulated cell death characterized by intracellular accumulation of iron and reactive oxygen species, inhibition of system Xc-,…”
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Are we getting closer to offering deep brain stimulation for treatment-resistant depression in clinical practice? by Qiu, Liming, Halpern, Casey H., Barbosa, Daniel A. N.

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Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders by Gil-Martins, Eva, Barbosa, Daniel José, Silva, Vera, Remião, Fernando, Silva, Renata

“…ABC (ATP-binding cassette) transporters represent one of the largest and most diverse superfamily of proteins in living species, playing an important role in…”
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Pilot study of responsive nucleus accumbens deep brain stimulation for loss-of-control eating by Shivacharan, Rajat S., Rolle, Camarin E., Barbosa, Daniel A. N., Cunningham, Tricia N., Feng, Austin, Johnson, Noriah D., Safer, Debra L., Bohon, Cara, Keller, Corey, Buch, Vivek P., Parker, Jonathon J., Azagury, Dan E., Tass, Peter A., Bhati, Mahendra T., Malenka, Robert C., Lock, James D., Halpern, Casey H.

“…Cravings that precede loss of control (LOC) over food consumption present an opportunity for intervention in patients with the binge eating disorder (BED). In…”
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UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice by Rijsketic, Daniel Ryskamp, Casey, Austen B, Barbosa, Daniel A N, Zhang, Xue, Hietamies, Tuuli M, Ramirez-Ovalle, Grecia, Pomrenze, Matthew B, Halpern, Casey H, Williams, Leanne M, Malenka, Robert C, Heifets, Boris D

“…The effects of context on the subjective experience of serotonergic psychedelics have not been fully examined in human neuroimaging studies, partly due to…”
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Focused ultrasound for functional neurosurgery by Lev-Tov, Lior, Barbosa, Daniel A. N., Ghanouni, Pejman, Halpern, Casey H., Buch, Vivek P.

“…Introduction Brain lesioning is a fundamental technique in the functional neurosurgery world. It has been investigated for decades and presented promising…”
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Human habit neural circuitry may be perturbed in eating disorders by Wang, Allan R, Kuijper, Fiene Marie, Barbosa, Daniel A N, Hagan, Kelsey E, Lee, Eric, Tong, Elizabeth, Choi, Eun Young, McNab, Jennifer A, Bohon, Cara, Halpern, Casey H

“…Circuit-based mechanisms mediating the development and execution of habitual behaviors involve complex cortical-striatal interactions that have been…”
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Molecular Motors in Myelination and Their Misregulation in Disease by Barbosa, Daniel José, Carvalho, Cátia, Costa, Inês, Silva, Renata

“…Molecular motors are cellular components involved in the intracellular transport of organelles and materials to ensure cell homeostasis. This is particularly…”
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Alzheimer’s disease: Insights and new prospects in disease pathophysiology, biomarkers and disease-modifying drugs by Monteiro, Ana R., Barbosa, Daniel J., Remião, Fernando, Silva, Renata

“…[Display omitted] •AD is the most predominant form of dementia, affecting millions of people worldwide.•The etiology of the disease is unknown and the approved…”
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A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport by Celestino, Ricardo, Henen, Morkos A, Gama, José B, Carvalho, Cátia, McCabe, Maxwell, Barbosa, Daniel J, Born, Alexandra, Nichols, Parker J, Carvalho, Ana X, Gassmann, Reto, Vögeli, Beat

“…All animal cells use the motor cytoplasmic dynein 1 (dynein) to transport diverse cargo toward microtubule minus ends and to organize and position microtubule…”
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Dynactin binding to tyrosinated microtubules promotes centrosome centration in C. elegans by enhancing dynein-mediated organelle transport by Barbosa, Daniel J, Duro, Joana, Prevo, Bram, Cheerambathur, Dhanya K, Carvalho, Ana X, Gassmann, Reto

“…The microtubule-based motor dynein generates pulling forces for centrosome centration and mitotic spindle positioning in animal cells. How the essential dynein…”
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Dynein directs prophase centrosome migration to control the stem cell division axis in the developing Caenorhabditis elegans epidermis by Carvalho, Cátia, Barbosa, Daniel J, Celestino, Ricardo, Zanin, Esther, Xavier Carvalho, Ana, Gassmann, Reto

“…Abstract The microtubule motor dynein is critical for the assembly and positioning of mitotic spindles. In Caenorhabditis elegans, these dynein functions have…”
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The insulo-opercular cortex encodes food-specific content under controlled and naturalistic conditions by Huang, Yuhao, Kakusa, Bina W., Feng, Austin, Gattas, Sandra, Shivacharan, Rajat S., Lee, Eric B., Parker, Jonathon J., Kuijper, Fiene M., Barbosa, Daniel A. N., Keller, Corey J., Bohon, Cara, Mikhail, Abanoub, Halpern, Casey H.

“…The insulo-opercular network functions critically not only in encoding taste, but also in guiding behavior based on anticipated food availability. However,…”
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Aberrant impulse control circuitry in obesity by Barbosa, Daniel A. N., Kuijper, Fiene Marie, Duda, Jeffrey, Wang, Allan R., Cartmell, Samuel C. D., Saluja, Sabir, Cunningham, Tricia, Shivacharan, Rajat S., Bhati, Mahendra T., Safer, Debra L., Lock, James D., Malenka, Robert C., de Oliveira-Souza, Ricardo, Williams, Nolan R., Grossman, Murray, Gee, James C., McNab, Jennifer A., Bohon, Cara, Halpern, Casey H.

“…The ventromedial prefrontal cortex (vmPFC) to nucleus accumbens (NAc) circuit has been implicated in impulsive reward-seeking. This disinhibition has been…”
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Diffusion Magnetic Resonance Imaging Tractography Guides Investigation of the Zona Incerta: A Novel Target for Deep Brain Stimulation by Saluja, Sabir, Qiu, Liming, Wang, Allan R., Campos, Gustavo, Seilheimer, Robert, McNab, Jennifer A., Haber, Suzanne N., Barbosa, Daniel A.N., Halpern, Casey H.

“…The zona incerta (ZI) is a subcortical structure primarily investigated in rodents that is implicated in various behaviors, ranging from motor control to…”
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Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study by Wu, Hemmings, Adler, Sarah, Azagury, Dan E, Bohon, Cara, Safer, Debra L, Barbosa, Daniel A N, Bhati, Mahendra T, Williams, Nolan R, Dunn, Laura B, Tass, Peter A, Knutson, Brian D, Yutsis, Maya, Fraser, Ayesha, Cunningham, Tricia, Richardson, Kara, Skarpaas, Tara L, Tcheng, Thomas K, Morrell, Martha J, Roberts, Laura Weiss, Malenka, Robert C, Lock, James D, Halpern, Casey H

“…Abstract BACKGROUND Loss of control (LOC) is a pervasive feature of binge eating, which contributes significantly to the growing epidemic of obesity;…”
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CRISPR-Cas technology in forensic investigations: Principles, applications, and ethical considerations by Sobral, Ana Filipa, Dinis-Oliveira, Ricardo Jorge, Barbosa, Daniel José

“…CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins) systems are adaptive immune systems originally present in…”
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Function of lipid droplet-organelle interactions in lipid homeostasis by Barbosa, Antonio Daniel, Siniossoglou, Symeon

“…Storage of non-polar lipids in ubiquitous eukaryotic organelles, lipid droplets (LDs), prevents the toxic consequences of unesterified fatty acids and provides…”
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An orexigenic subnetwork within the human hippocampus by Barbosa, Daniel A. N., Gattas, Sandra, Salgado, Juliana S., Kuijper, Fiene Marie, Wang, Allan R., Huang, Yuhao, Kakusa, Bina, Leuze, Christoph, Luczak, Artur, Rapp, Paul, Malenka, Robert C., Hermes, Dora, Miller, Kai J., Heifets, Boris D., Bohon, Cara, McNab, Jennifer A., Halpern, Casey H.

“…Only recently have more specific circuit-probing techniques become available to inform previous reports implicating the rodent hippocampus in orexigenic…”
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When biopsy goes wrong: a case series of misdiagnoses and complications from biopsies of masses of unknown origin potentially originating from a peripheral nerve by Guedes, Fernando, Henriques, Vinícius M, Torrão, Francisco L, Haikal, Neder P, Sanches, Gabriel E, Barbosa, Daniel A N, Marsicano, Felipe G, Rosa, Livia A N, Siquara, Ana C, Malessy, Martijn J A

“…Biopsies of peripheral nerve tumors (PNTs) are often used to plan an efficient treatment strategy. However, performing a biopsy is controversial when the mass…”
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