Search Results - "Barbieri, E."
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Environmental impact of biogenic silver nanoparticles in soil and aquatic organisms
Published in Chemosphere (Oxford) (01-01-2020)“…Synthetic silver nanoparticles (AgNPs) are being extensively used in our daily lives; however, they may also pose a risk to public health and environment…”
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The long tail of oncogenic drivers in prostate cancer
Published in Nature genetics (01-05-2018)“…Comprehensive genomic characterization of prostate cancer has identified recurrent alterations in genes involved in androgen signaling, DNA repair, and PI3K…”
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The Role of Gut Microbiome in the Pathogenesis of Prostate Cancer: A Prospective, Pilot Study
Published in Urology (Ridgewood, N.J.) (01-01-2018)“…To elucidate potential biomarkers or mechanistic principles involved with the gut microbiota and its impact on prostate cancer pathogenesis. We performed a…”
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FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes
Published in Nature (London) (01-07-2019)“…Mutations in the transcription factor FOXA1 define a unique subset of prostate cancers but the functional consequences of these mutations and whether they…”
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Clinical variability and molecular heterogeneity in prostate cancer
Published in Asian journal of andrology (01-07-2016)“…Prostate cancer is a clinically heterogeneous disease, with some men having indolent disease that can safely be observed, while others have aggressive, lethal…”
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DNA Repair in Prostate Cancer: Biology and Clinical Implications
Published in European urology (01-03-2017)“…Abstract Context For more precise, personalized care in prostate cancer (PC), a new classification based on molecular features relevant for prognostication and…”
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Discordance in receptor status between primary and recurrent breast cancer has a prognostic impact: a single-Institution analysis
Published in Annals of oncology (01-01-2013)“…Tumor phenotype may change during breast cancer progression. This study evaluates the prognostic impact of receptor discordance between paired primaries and…”
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Implementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review
Published in Antimicrobial resistance & infection control (03-01-2020)“…Antibiotics are the most common medicines prescribed to children in hospitals and the community, with a high proportion of potentially inappropriate use…”
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SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling
Published in Cancer cell (13-03-2017)“…Recurrent point mutations in SPOP define a distinct molecular subclass of prostate cancer. Here, we describe a mouse model showing that mutant SPOP drives…”
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Loss of HER2 positivity and prognosis after neoadjuvant therapy in HER2-positive breast cancer patients
Published in Annals of oncology (01-12-2013)“…Emerging literature data are showing that a change in human epidermal growth factor receptor (HER2) status adversely affects breast cancer patient's prognosis…”
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Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
Published in Nature medicine (01-09-2017)“…Recurrent mutations in SPOP -encoding a Cullin 3-based E3 ubiquitin ligase- in prostate cancer disrupt the recognition and degradation of ubiquitination…”
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Recycling of spent ion-lithium batteries as cobalt hydroxide, and cobalt oxide films formed under a conductive glass substrate, and their electrochemical properties
Published in Journal of power sources (10-12-2014)“…In this work, Co(OH) sub(2) and Co sub(3)O sub(4) films have been obtained using a solution to leach the cathodes of spent Li-ion batteries. The Co(OH) sub(2)…”
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The Mutational Landscape of Prostate Cancer
Published in European urology (01-10-2013)“…Abstract Context Prostate cancer (PCa) is a clinically heterogeneous disease with marked variability in patient outcomes. Molecular characterization has…”
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The Emergence of Precision Urologic Oncology: A Collaborative Review on Biomarker-driven Therapeutics
Published in European urology (01-02-2017)“…Abstract Context Biomarker-driven cancer therapy, also referred to as precision oncology, has received increasing attention for its promise of improving…”
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CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis
Published in Cancer cell (15-04-2019)“…Deletion of the gene encoding the chromatin remodeler CHD1 is among the most common alterations in prostate cancer (PCa); however, the tumor-suppressive…”
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Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover
Published in Proceedings of the National Academy of Sciences - PNAS (23-04-2013)“…The p160 steroid receptor coactivators (SRCs) SRC-1, SRC-2 [nuclear receptor coactivator (NCOA)2], and SRC-3 [amplified in breast cancer 1 (AIB1)/NCOA3] are…”
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Mechanics of mutable hierarchical composite cellular materials
Published in Mechanics of materials (01-09-2018)“…•This paper, inspired by the configuration of the hygroscopic keel tissue of the ice plant, deals with the analysis of a two-dimensional cellular material made…”
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A new weight-function enrichment in meshless methods for multiple cracks in linear elasticity
Published in International journal for numerical methods in engineering (13-04-2012)“…SUMMARY A new enriched weight function for meshless methods is proposed for the numerical treatment of multiple arbitrary cracks in two dimensions. The main…”
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Creatine as an antioxidant
Published in Amino acids (01-05-2011)“…Creatine monohydrate (Cr), the most diffuse supplement in the sports industry, is receiving greater attention because of its beneficial effects in a wide…”
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SPOP mutation leads to genomic instability in prostate cancer
Published in eLife (16-09-2015)“…Genomic instability is a fundamental feature of human cancer often resulting from impaired genome maintenance. In prostate cancer, structural genomic…”
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