Search Results - "Barbie, Thanh"

De Novo Stage 4 Metastatic Breast Cancer: A Surgical Disease? by Barbie, Thanh U., Golshan, Mehra

Get full text

Omission of Surgical Axillary Lymph Node Staging in Patients with Tubular Breast Cancer by Özkurt, Enver, Wong, Stephanie, Rhei, Esther, Golshan, Mehra, Brock, Jane, Barbie, Thanh U.

“…Background With more effective screening and treatment strategies, there is debate over whether surgical axillary staging should be deescalated for patients…”
Get full text

Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth by Barbie, Thanh U, Alexe, Gabriela, Aref, Amir R, Li, Shunqiang, Zhu, Zehua, Zhang, Xiuli, Imamura, Yu, Thai, Tran C, Huang, Ying, Bowden, Michaela, Herndon, John, Cohoon, Travis J, Fleming, Timothy, Tamayo, Pablo, Mesirov, Jill P, Ogino, Shuji, Wong, Kwok-Kin, Ellis, Matthew J, Hahn, William C, Barbie, David A, Gillanders, William E

“…Triple-negative breast cancers (TNBCs) are a heterogeneous set of cancers that are defined by the absence of hormone receptor expression and HER2…”
Get full text

MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer by Kitajima, Shunsuke, Tani, Tetsuo, Springer, Benjamin F., Campisi, Marco, Osaki, Tatsuya, Haratani, Koji, Chen, Minyue, Knelson, Erik H., Mahadevan, Navin R., Ritter, Jessica, Yoshida, Ryohei, Köhler, Jens, Ogino, Atsuko, Nozawa, Ryu-Suke, Sundararaman, Shriram K., Thai, Tran C., Homme, Mizuki, Piel, Brandon, Kivlehan, Sophie, Obua, Bonje N., Purcell, Connor, Yajima, Mamiko, Barbie, Thanh U., Lizotte, Patrick H., Jänne, Pasi A., Paweletz, Cloud P., Gokhale, Prafulla C., Barbie, David A.

“…KRAS-LKB1 (KL) mutant lung cancers silence STING owing to intrinsic mitochondrial dysfunction, resulting in T cell exclusion and resistance to programmed cell…”
Get full text

Phosphorylation of RAB7 by TBK1/IKKε Regulates Innate Immune Signaling in Triple-Negative Breast Cancer by Ritter, Jessica L, Zhu, Zehua, Thai, Tran C, Mahadevan, Navin R, Mertins, Philipp, Knelson, Erik H, Piel, Brandon P, Han, Saemi, Jaffe, Jacob D, Carr, Steven A, Barbie, David A, Barbie, Thanh U

“…Triple-negative breast cancer (TNBC) is a heterogeneous disease enriched for mutations in PTEN and dysregulation of innate immune signaling. Here, we…”
Get full text

Use of Ex Vivo Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for HER2 Mutant Non-Small Cell Lung Cancer by Ivanova, Elena, Kuraguchi, Mari, Xu, Man, Portell, Andrew J, Taus, Luke, Diala, Irmina, Lalani, Alshad S, Choi, Jihyun, Chambers, Emily S, Li, Shuai, Liu, Shengwu, Chen, Ting, Barbie, Thanh U, Oxnard, Geoffrey R, Haworth, Jacob J, Wong, Kwok-Kin, Dahlberg, Suzanne E, Aref, Amir A, Barbie, David A, Bahcall, Magda, Paweletz, Cloud P, Jänne, Pasi A

“…Evaluating drug responses using primary patient-derived cells represents a potentially rapid and efficient approach to screening for new treatment approaches…”
Get full text

Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit by Zhu, Zehua, Aref, Amir R, Cohoon, Travis J, Barbie, Thanh U, Imamura, Yu, Yang, Shenghong, Moody, Susan E, Shen, Rhine R, Schinzel, Anna C, Thai, Tran C, Reibel, Jacob B, Tamayo, Pablo, Godfrey, Jason T, Qian, Zhi Rong, Page, Asher N, Maciag, Karolina, Chan, Edmond M, Silkworth, Whitney, Labowsky, Mary T, Rozhansky, Lior, Mesirov, Jill P, Gillanders, William E, Ogino, Shuji, Hacohen, Nir, Gaudet, Suzanne, Eck, Michael J, Engelman, Jeffrey A, Corcoran, Ryan B, Wong, Kwok-Kin, Hahn, William C, Barbie, David A

“…Although the roles of mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K) signaling in KRAS-driven tumorigenesis are well established,…”
Get more information

How Often Does Retrieval of a Clipped Lymph Node Change Adjuvant Therapy Recommendations? A Prospective, Consecutive, Patient Cohort Study by Weiss, Anna, King, Claire, Grossmith, Samantha, Portnow, Leah, Raza, Sughra, Nakhlis, Faina, Dominici, Laura, Barbie, Thanh, Minami, Christina, Nimbkar, Suniti, Rhei, Esther, Mittendorf, Elizabeth A., King, Tari A.

“…Background Prior studies examining sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NAC) for cN1 patients have demonstrated that 20% of…”
Get full text

TREX1 Inactivation Unleashes Cancer Cell STING-Interferon Signaling and Promotes Antitumor Immunity by Tani, Tetsuo, Mathsyaraja, Haritha, Campisi, Marco, Li, Ze-Hua, Haratani, Koji, Fahey, Caroline G, Ota, Keiichi, Mahadevan, Navin R, Shi, Yingxiao, Saito, Shin, Mizuno, Kei, Thai, Tran C, Sasaki, Nobunari, Homme, Mizuki, Yusuf, Choudhury Fabliha B, Kashishian, Adam, Panchal, Jipsa, Wang, Min, Wolf, Benjamin J, Barbie, Thanh U, Paweletz, Cloud P, Gokhale, Prafulla C, Liu, David, Uppaluri, Ravindra, Kitajima, Shunsuke, Cain, Jennifer, Barbie, David A

“…A substantial fraction of cancers evade immune detection by silencing Stimulator of Interferon Genes (STING)-Interferon (IFN) signaling. Therapeutic…”
Get more information

Gestational Pseudoangiomatous Stromal Hyperplasia Presenting as Gigantomastia: A Case Report of a Rare Breast Entity with Clinical Recommendations by a Multidisciplinary Team by Wang, S. Jennifer, Maheswaran, Shivi, Reiss, Rosemary, Portnow, Leah H., Brock, Jane, Novak, Lara, Erdmann-Sager, Jessica, Barbie, Thanh U.

“…Introduction. Pseudoangiomatous stromal hyperplasia (PASH) presenting as gigantomastia is rare in pregnancy but can result in severe clinical consequences for…”
Get full text

ASO Visual Abstract: How Often Does Retrieval of a Clipped Lymph Node Change Adjuvant Therapy Recommendations? A Prospective Consecutive Patient Cohort Study by Weiss, Anna, King, Claire, Grossmith, Samantha, Portnow, Leah, Raza, Sughra, Nakhlis, Faina, Dominici, Laura, Barbie, Thanh, Minami, Christina, Nimbkar, Suniti, Rhei, Esther, Mittendorf, Elizabeth A., King, Tari A.

Get full text

Management of Premenopausal Women with Neoadjuvant Endocrine Therapy: A Single-Institution Experience by Barbie, Thanh U., Ma, Cynthia, Margenthaler, Julie A.

“…Background In postmenopausal women with hormone receptor (HR)-positive breast cancer, neoadjuvant endocrine therapy (ET) provides effective downstaging of…”
Get full text

Impact of Prepectoral vs. Subpectoral Tissue Expander Placement on Post-mastectomy Radiation Therapy Delivery: A Retrospective Cohort Study by Copeland-Halperin, Libby R, Lyatskaya, Yulia, Bellon, Jennifer R, Dey, Tanujit, Carty, Matthew J, Barbie, Thanh, Erdmann-Sager, Jessica

“…Implant-based reconstruction is the most common method of postmastectomy reconstruction. Many patients require postmastectomy radiation (PMRT). Tissue…”
Get full text

Mullerian Inhibiting Substance Inhibits Cervical Cancer Cell Growth via a Pathway Involving p130 and p107 by Barbie, Thanh U., Barbie, David A., MacLaughlin, David T., Maheswaran, Shyamala, Donahoe, Patricia K.

“…In addition to causing regression of the Mullerian duct in the male embryo, Mullerian Inhibiting Substance (MIS) inhibits the growth of epithelial ovarian…”
Get full text

Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses by Cañadas, Israel, Thummalapalli, Rohit, Kim, Jong Wook, Kitajima, Shunsuke, Jenkins, Russell William, Christensen, Camilla Laulund, Campisi, Marco, Kuang, Yanan, Zhang, Yanxi, Gjini, Evisa, Zhang, Gao, Tian, Tian, Sen, Debattama Rai, Miao, Diana, Imamura, Yu, Thai, Tran, Piel, Brandon, Terai, Hideki, Aref, Amir Reza, Hagan, Timothy, Koyama, Shohei, Watanabe, Masayuki, Baba, Hideo, Adeni, Anika Elise, Lydon, Christine Anne, Tamayo, Pablo, Wei, Zhi, Herlyn, Meenhard, Barbie, Thanh Uyen, Uppaluri, Ravindra, Sholl, Lynnette Marie, Sicinska, Ewa, Sands, Jacob, Rodig, Scott, Wong, Kwok Kin, Paweletz, Cloud Peter, Watanabe, Hideo, Barbie, David Allen

“…Mesenchymal tumor subpopulations secrete pro-tumorigenic cytokines and promote treatment resistance 1 – 4 . This phenomenon has been implicated in…”
Get full text

Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids by Jenkins, Russell W, Aref, Amir R, Lizotte, Patrick H, Ivanova, Elena, Stinson, Susanna, Zhou, Chensheng W, Bowden, Michaela, Deng, Jiehui, Liu, Hongye, Miao, Diana, He, Meng Xiao, Walker, William, Zhang, Gao, Tian, Tian, Cheng, Chaoran, Wei, Zhi, Palakurthi, Sangeetha, Bittinger, Mark, Vitzthum, Hans, Kim, Jong Wook, Merlino, Ashley, Quinn, Max, Venkataramani, Chandrasekar, Kaplan, Joshua A, Portell, Andrew, Gokhale, Prafulla C, Phillips, Bart, Smart, Alicia, Rotem, Asaf, Jones, Robert E, Keogh, Lauren, Anguiano, Maria, Stapleton, Lance, Jia, Zhiheng, Barzily-Rokni, Michal, Cañadas, Israel, Thai, Tran C, Hammond, Marc R, Vlahos, Raven, Wang, Eric S, Zhang, Hua, Li, Shuai, Hanna, Glenn J, Huang, Wei, Hoang, Mai P, Piris, Adriano, Eliane, Jean-Pierre, Stemmer-Rachamimov, Anat O, Cameron, Lisa, Su, Mei-Ju, Shah, Parin, Izar, Benjamin, Thakuria, Manisha, LeBoeuf, Nicole R, Rabinowits, Guilherme, Gunda, Viswanath, Parangi, Sareh, Cleary, James M, Miller, Brian C, Kitajima, Shunsuke, Thummalapalli, Rohit, Miao, Benchun, Barbie, Thanh U, Sivathanu, Vivek, Wong, Joshua, Richards, William G, Bueno, Raphael, Yoon, Charles H, Miret, Juan, Herlyn, Meenhard, Garraway, Levi A, Van Allen, Eliezer M, Freeman, Gordon J, Kirschmeier, Paul T, Lorch, Jochen H, Ott, Patrick A, Hodi, F Stephen, Flaherty, Keith T, Kamm, Roger D, Boland, Genevieve M, Wong, Kwok-Kin, Dornan, David, Paweletz, Cloud Peter, Barbie, David A

“…systems that incorporate features of the tumor microenvironment and model the dynamic response to immune checkpoint blockade (ICB) may facilitate efforts in…”
Get more information

Impact of Residual Nodal Disease Burden on Technical Outcomes of Sentinel Lymph Node Biopsy for Node-Positive (cN1) Breast Cancer Patients Treated with Neoadjuvant Chemotherapy by Laws, Alison, Hughes, Melissa E., Hu, Jiani, Barry, William T., Dominici, Laura, Nakhlis, Faina, Barbie, Thanh, Duggan, Margaret, Weiss, Anna, Rhei, Esther, Carter, Katharine, Nimbkar, Suniti, Schnitt, Stuart J., King, Tari A.

“…Background Recent trials have demonstrated the feasibility of sentinel lymph node biopsy (SLNB) for cN1 breast cancer patients after neoadjuvant chemotherapy…”
Get full text

Abstract 6431: Targeting Rab7-mediated STING degradation to amplify therapeutic STING agonism in TNBC by Zhang, Yuqing, Ritter, Jessica L., Thai, Tran C., Dillon, Deborah A., Barbie, David A., Barbie, Thanh U.

“…STING (Stimulator of interferon genes), encoded by TMEM173, is a critical regulator of the innate immune response to cytoplasmic double stranded DNA in cancer…”
Get full text

Multidisciplinary Management of the Axilla in Patients with cT1-T2 N0 Breast Cancer Undergoing Primary Mastectomy: Results from a Prospective Single-Institution Series by Grossmith, Samantha, Nguyen, Anvy, Hu, Jiani, Plichta, Jennifer K., Nakhlis, Faina, Cutone, Linda, Dominici, Laura, Golshan, Mehra, Duggan, Margaret, Carter, Katharine, Rhei, Esther, Barbie, Thanh, Calvillo, Katherina, Nimbkar, Suniti, Bellon, Jennifer, Wong, Julia, Punglia, Rinaa, Barry, William, King, Tari A.

“…Background The after mapping of the axilla: radiotherapy or surgery (AMAROS) trial concluded that for patients with cT1-2 N0 breast cancer and one or two…”
Get full text

Impact of residual nodal disease burden on sentinel node mapping and accuracy of intraoperative frozen section in node positive (cN1) breast cancer patients treated with neoadjuvant chemotherapy (NAC) by Laws, Alison, Hughes, Melissa E, Hu, Jiani, Barry, William Thomas, Dominici, Laura Stewart, Nakhlis, Faina, Barbie, Thanh, Duggan, Margaret M., Weiss, Anna, Rhei, Esther, Carter, Katharine, Calvillo, Katherina, Nimbkar, Suniti, Schnitt, Stuart J., King, Tari A.

“…Abstract only…”
Get full text