Seroprevalence for measles among healthcare workers in Madrid, Spain

Seroprevalence for measles among healthcare workers in Madrid, Spain

Immunity of healthcare workers (HCWs) against measles is a particular concern. They are more likely to contract it than the general population due to their occupational exposure which may cause a nosocomial outbreak. To assess the measles immune status of HCWs at five Spanish university hospitals. S...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of hospital infection Vol. 147; pp. 63 - 67
Main Authors: Cuerda, A.de la, González, M.I.Tejeda, López Aparicio, A., Monfort Vinuesa, C., López Pedraza, M.J., Isidoro, B., Mayordomo-Cava, J., Barberán, L.C., Collazos, J., Pérez-Ortiz, J.M., Barberán, J.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-05-2024
Subjects:
Adult
Antibodies, Viral - blood
Female
Health Personnel - statistics & numerical data
Healthcare workers
Hospitals, University
Humans
Immunoglobulin G - blood
Luminescent Measurements
Male
Measles
Measles - epidemiology
Measles - immunology
Measles - prevention & control
Middle Aged
Prospective Studies
Seroepidemiologic Studies
Seroprevalence
Spain
Spain - epidemiology
Vaccination
Young Adult
Spain
Healthcare workers
Measles
Vaccination
Seroprevalence
Spain
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Immunity of healthcare workers (HCWs) against measles is a particular concern. They are more likely to contract it than the general population due to their occupational exposure which may cause a nosocomial outbreak. To assess the measles immune status of HCWs at five Spanish university hospitals. Serologic testing (IgG) for measles by chemiluminescence indirect immunoassay (CLIA) was carried out prospectively and consecutively in HCWs from five university hospitals. All HCWs were classified into four epidemiological groups: vaccinated individuals, those with a history of measles disease, subjects with no history of measles or vaccination, and those who did not know whether they had measles or were vaccinated, and into five professional categories: physicians, nurses, nursing assistants, other clinical workers and non-clinical workers. A logistic regression model was constructed to identify the factors independently associated with immunity to measles. The study group was composed of 2157 HCWs. 89% had protective antibodies against measles. Of the 238 non-immune HCWs, 199 (83.6%) had been vaccinated, compared with 1084 of the 1919 (56.5%) immune individuals (P<0.0001). The parameters significantly predictive of having protective antibodies against measles were: older age (P<0.0001), epidemiological status (P=0.0002, mainly past measles disease), and professional category (P=0.02, in particular nurses). This study shows that HCWs, including those previously vaccinated, are currently at risk of measles and suggests that those with a natural history of infection are better protected. Therefore, knowledge and maintenance of immunity to measles are an essential part of infection control among HCWs.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0195-6701
1532-2939
DOI:10.1016/j.jhin.2023.11.006