Search Results - "Barber, Philip"

Dementia risk and prevention by targeting modifiable vascular risk factors by Tariq, Sana, Barber, Philip A.

“…The incidence of dementia is expected to double in the next 20 years and will contribute to heavy social and economic burden. Dementia is caused by neuronal…”
Get full text

Quantitative detection of grey and white matter amyloid pathology using a combination of K114 and CRANAD-3 fluorescence by Stepanchuk, Anastasiia A., Barber, Philip A., Lashley, Tammaryn, Joseph, Jeffrey T., Stys, Peter K.

“…Alzheimer's disease (AD) is a neurodegenerative disease that exacts a huge toll on the patient, the healthcare system and society in general. Abundance and…”
Get full text

White matter tract microstructure and cognitive performance after transient ischemic attack by Tariq, Sana, Tsang, Adrian, Wang, Meng, Reaume, Noaah, Carlson, Helen, Sajobi, Tolulope T, Longman, Richard Stewart, Smith, Eric E, Frayne, Richard, d'Esterre, Christopher D, Coutts, Shelagh B, Barber, Philip A

“…Background and purpose Patients with transient ischemic attack (TIA) show evidence of cognitive impairment but the reason is not clear. Measurement of…”
Get full text

The Cognitive Sequelae of Transient Ischemic Attacks-Recent Insights and Future Directions by Ganesh, Aravind, Barber, Philip A

“…There is now considerable evidence that Transient Ischemic Attack (TIA) carries important sequelae beyond the risk of recurrent stroke, particularly with…”
Get full text

Magnetic resonance imaging of ischemia viability thresholds and the neurovascular unit by Barber, Philip A

“…Neuroimaging has improved our understanding of the evolution of stroke at discreet time points helping to identify irreversibly damaged and potentially…”
Get full text

Protection against recurrent stroke with resveratrol: endothelial protection by Clark, Darren, Tuor, Ursula I, Thompson, Roger, Institoris, Adam, Kulynych, Angela, Zhang, Xu, Kinniburgh, David W, Bari, Ferenc, Busija, David W, Barber, Philip A

“…Despite increased risk of a recurrent stroke following a minor stroke, information is minimal regarding the interaction between injurious mild cerebral…”
Get full text

Tenecteplase–Tissue-Type Plasminogen Activator Evaluation for Minor Ischemic Stroke With Proven Occlusion by Coutts, Shelagh B, Dubuc, Véronique, Mandzia, Jennifer, Kenney, Carol, Demchuk, Andrew M, Smith, Eric E, Subramaniam, Suresh, Goyal, Mayank, Patil, Shivanand, Menon, Bijoy K, Barber, Philip A, Dowlatshahi, Dar, Field, Thalia, Asdaghi, Negar, Camden, Marie-Christine, Hill, Michael D

“…BACKGROUND AND PURPOSE—Minor stroke and transient ischemic attack with an intracranial occlusion are associated with neurological deterioration and disability…”
Get full text

Extent of Hypoattenuation on CT Angiography Source Images Predicts Functional Outcome in Patients With Basilar Artery Occlusion by PUETZ, Volker, SYLAJA, P. N, SHARMA, Pranshu, GOYAL, Mayank, GAHN, Georg, VON KUMMER, Ruediger, DEMCHUK, Andrew M, COUTTS, Shelagh B, HILL, Michael D, DZIALOWSKI, Imanuel, MUELLER, Pia, BECKER, Ulf, URBAN, Gabriele, O'REILLY, Christine, BARBER, Philip A

“…Quantification of early ischemic changes (EIC) may predict functional outcome in patients with basilar artery occlusion (BAO). We tested the validity of a…”
Get full text

Infrared optical imaging of matrix metalloproteinases (MMPs) up regulation following ischemia reperfusion is ameliorated by hypothermia by Barber, Philip A, Rushforth, David, Agrawal, Smriti, Tuor, Ursula I

“…We investigated the use of a new MMP activatable probe MMPSense™ 750 FAST (MMPSense750) for in-vivo visualization of early MMP activity in ischemic stroke…”
Get full text

The neuroimaging of neurodegenerative and vascular disease in the secondary prevention of cognitive decline by Schaeffer, Morgan J, Chan, Leona, Barber, Philip A

“…Structural brain changes indicative of dementia occur up to 20 years before the onset of clinical symptoms. Efforts to modify the disease process after the…”
Get full text

Development and characterization of a novel, antimicrobial, sterile hydrogel dressing for burn wounds: single-step production with gamma irradiation creates silver nanoparticles and radical polymerization by Boonkaew, Benjawan, Barber, Philip M, Rengpipat, Sirirat, Supaphol, Pitt, Kempf, Margit, He, Jibao, John, Vijay T, Cuttle, Leila

“…Patients with burn wounds are susceptible to wound infection and sepsis. This research introduces a novel burn wound dressing that contains silver…”
Get more information

Genetic determinants of white matter hyperintensities and amyloid angiopathy in familial Alzheimer's disease by Ryan, Natalie S, Biessels, Geert-Jan, Kim, Lois, Nicholas, Jennifer M, Barber, Philip A, Walsh, Phoebe, Gami, Priya, Morris, Huw R, Bastos-Leite, António J, Schott, Jonathan M, Beck, Jon, Mead, Simon, Chavez-Gutierrez, Lucia, de Strooper, Bart, Rossor, Martin N, Revesz, Tamas, Lashley, Tammaryn, Fox, Nick C

“…Abstract Familial Alzheimer's disease (FAD) treatment trials raise interest in the variable occurrence of cerebral amyloid angiopathy (CAA); an emerging…”
Get full text

Reduced blood brain barrier breakdown in P-selectin deficient mice following transient ischemic stroke: a future therapeutic target for treatment of stroke by Jin, Albert Y, Tuor, Ursula I, Rushforth, David, Kaur, Jaspreet, Muller, Robert N, Petterson, Jodie Lee, Boutry, Sébastien, Barber, Philip A

“…The link between early blood- brain barrier (BBB) breakdown and endothelial cell activation in acute stroke remain poorly defined. We hypothesized that…”
Get full text

Combined Atlas and Convolutional Neural Network-Based Segmentation of the Hippocampus from MRI According to the ADNI Harmonized Protocol by Nobakht, Samaneh, Schaeffer, Morgan, Forkert, Nils D, Nestor, Sean, E Black, Sandra, Barber, Philip, The Alzheimer's Disease Neuroimaging Initiative

“…Hippocampus atrophy is an early structural feature that can be measured from magnetic resonance imaging (MRI) to improve the diagnosis of neurological…”
Get full text

Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy by Barber, Philip A, Demchuk, Andrew M, Zhang, Jinjin, Buchan, Alastair M

“…Computed tomography (CT) must be done before thrombolytic treatment of hyperacute ischaemic stroke, but the significance of early ischaemic change on CT is…”
Get full text

Imaging and Baseline Predictors of Cognitive Performance in Minor Ischemic Stroke and Patients With Transient Ischemic Attack at 90 Days by Mandzia, Jennifer L, Smith, Eric E, Horton, Myles, Hanly, Patrick, Barber, Philip A, Godzwon, Catherine, Donaldson, Emily, Asdaghi, Negar, Patel, Shiel, Coutts, Shelagh B

“…Few studies have examined predictors of cognitive impairment after minor ischemic stroke and transient ischemic attack (TIA). We examined clinical and imaging…”
Get full text

Nodal staging in lung cancer: a risk stratification model for lymph nodes classified as negative by EBUS-TBNA by Evison, Matthew, Morris, Julie, Martin, Julie, Shah, Rajesh, Barber, Philip V, Booton, Richard, Crosbie, Philip A J

“…Over the last 10 years, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become established as the first-line nodal staging…”
Get more information

Infarct in a New Territory After Treatment Administration in the ESCAPE Randomized Controlled Trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion With Emphasis on Minimizing CT to Recanalization Times) by Ganesh, Aravind, Al-Ajlan, Fahad S, Sabiq, Farahna, Assis, Zarina, Rempel, Jeremy L, Butcher, Kenneth, Thornton, John, Kelly, Peter, Roy, Daniel, Poppe, Alexandre Y, Jovin, Tudor G, Devlin, Thomas, Baxter, Blaise W, Krings, Timo, Casaubon, Leanne K, Frei, Donald F, Choe, Hana, Tampieri, Donatella, Teitelbaum, Jeanne, Lum, Cheemun, Mandzia, Jennifer, Phillips, Stephen J, Bang, Oh Young, Almekhlafi, Mohammed A, Coutts, Shelagh B, Barber, Philip A, Sajobi, Tolulope, Demchuk, Andrew M, Eesa, Muneer, Hill, Michael D, Goyal, Mayank, Menon, Bijoy K

“…BACKGROUND AND PURPOSE—Infarct in a new previously unaffected territory (INT) is a potential complication of endovascular treatment. We applied a recently…”
Get full text

Recurrent mild cerebral ischemia: enhanced brain injury following acute compared to subacute recurrence in the rat by Tuor, Ursula I, Zhao, Zonghang, Barber, Philip A, Qiao, Min

“…In the current study, a transient cerebral ischemia producing selective cell death was designated a mild ischemic insult. A comparable insult in humans is a…”
Get full text

Platelet function/reactivity testing and prediction of risk of recurrent vascular events and outcomes after TIA or ischaemic stroke: systematic review and meta-analysis by Lim, Soon Tjin, Thijs, Vincent, Murphy, Stephen J. X., Fernandez-Cadenas, Israel, Montaner, Joan, Offiah, Chika, Marquardt, Lars, Kelly, Peter J., Bath, Philip M., Lim, Su-Yin, Ford, Gary A., Norrving, Bo, Cox, Dermot, Prodan, Calin I., Barber, Philip A., Werring, David J., Perry, Richard, Zgaga, Lina, Dawson, Jesse, McCabe, Dominick J. H.

“…Background The prevalence of ex vivo ‘high on-treatment platelet reactivity (HTPR)’ and its relationship with recurrent vascular events/outcomes in patients…”
Get full text