Search Results - "Barber, Bridget E"
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Plasmodium knowlesi Malaria in Sabah, Malaysia, 2015–2017: Ongoing Increase in Incidence Despite Near-elimination of the Human-only Plasmodium Species
Published in Clinical infectious diseases (16-01-2020)“…Abstract Background Malaysia aims to eliminate malaria by 2020. However, while cases of Plasmodium falciparum and Plasmodium vivax have decreased…”
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Deaths From Plasmodium knowlesi Malaria: Case Series and Systematic Review
Published in Clinical infectious diseases (30-10-2019)“…Plasmodium knowlesi causes severe and fatal malaria, and incidence in Southeast Asia is increasing. Factors associated with death are not clearly defined. All…”
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Platelets kill circulating parasites of all major Plasmodium species in human malaria
Published in Blood (20-09-2018)“…Platelets are understood to assist host innate immune responses against infection, although direct evidence of this function in any human disease, including…”
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Age-Related Clinical Spectrum of Plasmodium knowlesi Malaria and Predictors of Severity
Published in Clinical infectious diseases (18-07-2018)“…Patients with knowlesi malaria were older and had lower parasitemia compared to human-only species. Severe knowlesi malaria occurred only in adults. Anemia was…”
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World Malaria Report: time to acknowledge Plasmodium knowlesi malaria
Published in Malaria journal (31-03-2017)“…The 2016 World Health Organization (WHO) World Malaria Report documents substantial progress towards control and elimination of malaria. However, major…”
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Parasite biomass-related inflammation, endothelial activation, microvascular dysfunction and disease severity in vivax malaria
Published in PLoS pathogens (01-01-2015)“…Plasmodium vivax can cause severe malaria, however its pathogenesis is poorly understood. In contrast to P. falciparum, circulating vivax parasitemia is low,…”
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Limitations of microscopy to differentiate Plasmodium species in a region co-endemic for Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi
Published in Malaria journal (08-01-2013)“…In areas co-endemic for multiple Plasmodium species, correct diagnosis is crucial for appropriate treatment and surveillance. Species misidentification by…”
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The Treatment of Plasmodium knowlesi Malaria
Published in Trends in parasitology (01-03-2017)“…Plasmodium knowlesi occurs across Southeast Asia and is the most common cause of malaria in Malaysia. High parasitaemias can develop rapidly, and the risk of…”
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Genomic analysis of a pre-elimination Malaysian Plasmodium vivax population reveals selective pressures and changing transmission dynamics
Published in Nature communications (03-07-2018)“…The incidence of Plasmodium vivax infection has declined markedly in Malaysia over the past decade despite evidence of high-grade chloroquine resistance. Here…”
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Increasing incidence of Plasmodium knowlesi malaria following control of P. falciparum and P. vivax Malaria in Sabah, Malaysia
Published in PLoS neglected tropical diseases (01-01-2013)“…The simian parasite Plasmodium knowlesi is a common cause of human malaria in Malaysian Borneo and threatens the prospect of malaria elimination. However,…”
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Neutrophil activation, acute lung injury and disease severity in Plasmodium knowlesi malaria
Published in PLoS neglected tropical diseases (16-08-2024)“…The risk of severe malaria from the zoonotic parasite Plasmodium knowlesi approximates that from P. falciparum. In severe falciparum malaria, neutrophil…”
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Falling Plasmodium knowlesi Malaria Death Rate among Adults despite Rising Incidence, Sabah, Malaysia, 2010-2014
Published in Emerging infectious diseases (01-01-2016)“…Deaths from Plasmodium knowlesi malaria have been linked to delayed parenteral treatment. In Malaysia, early intravenous artesunate is now recommended for all…”
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Changing epidemiology of malaria in Sabah, Malaysia: increasing incidence of Plasmodium knowlesi
Published in Malaria journal (02-10-2014)“…While Malaysia has had great success in controlling Plasmodium falciparum and Plasmodium vivax, notifications of Plasmodium malariae and the microscopically…”
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Diagnostic accuracy and limit of detection of ten malaria parasite lactate dehydrogenase-based rapid tests for Plasmodium knowlesi and P. falciparum
Published in Frontiers in cellular and infection microbiology (17-10-2022)“…causes zoonotic malaria across Southeast Asia. First-line diagnostic microscopy cannot reliably differentiate from other human malaria species. Rapid…”
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Positron emission tomography and magnetic resonance imaging in experimental human malaria to identify organ-specific changes in morphology and glucose metabolism: A prospective cohort study
Published in PLoS medicine (26-05-2021)“…Background Plasmodium vivax has been proposed to infect and replicate in the human spleen and bone marrow. Compared to Plasmodium falciparum , which is known…”
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Effects of Aging on Parasite Biomass, Inflammation, Endothelial Activation, Microvascular Dysfunction and Disease Severity in Plasmodium knowlesi and Plasmodium falciparum Malaria
Published in The Journal of infectious diseases (15-06-2017)“…Background. In populations pauci-immune to malaria, risk of severe malaria increases with age. This is particularly apparent in Plasmodium knowlesi malaria…”
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Single cell transcriptomics shows that malaria promotes unique regulatory responses across multiple immune cell subsets
Published in Nature communications (15-11-2023)“…Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell subsets, which protects from immunopathogenesis, but also hampers the…”
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Artesunate–mefloquine versus chloroquine for treatment of uncomplicated Plasmodium knowlesi malaria in Malaysia (ACT KNOW): an open-label, randomised controlled trial
Published in The Lancet infectious diseases (01-02-2016)“…Summary Background The zoonotic parasite Plasmodium knowlesi has become the most common cause of human malaria in Malaysia and is present throughout much of…”
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Endothelial glycocalyx degradation and disease severity in Plasmodium vivax and Plasmodium knowlesi malaria
Published in Scientific reports (07-05-2021)“…Degradation of the endothelial glycocalyx is associated with mortality in adult falciparum malaria. However, its role in the pathogenesis of non-falciparum…”
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Evaluation of a point-of-care haemozoin assay (Gazelle device) for rapid detection of Plasmodium knowlesi malaria
Published in Scientific reports (23-03-2023)“…Plasmodium knowlesi is the major cause of zoonotic malaria in Southeast Asia. Rapid and accurate diagnosis enables effective clinical management. A novel…”
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