Search Results - "Barbee, K. A"

Computational Model of Nitric Oxide Production and Transport in a Parallel Plate Flow Chamber by Fadel, A. A, Barbee, K. A, Jaron, D

“…We developed a mathematical model to investigate the production and transport of nitric oxide (NO) generated by a monolayer of cultured endothelial cells…”
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An in vitro model of the tumor-lymphatic microenvironment with simultaneous transendothelial and luminal flows reveals mechanisms of flow enhanced invasion by Pisano, M, Triacca, V, Barbee, K A, Swartz, M A

“…The most common cancers, including breast and skin, disseminate initially through the lymphatic system, yet the mechanisms by which tumor cells home towards,…”
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Heterogeneous response of microvascular endothelial cells to shear stress by Hong, D, Jaron, D, Buerk, D G, Barbee, K A

“…We investigated changes in calcium concentration in cultured bovine aortic endothelial cells (BAECs) and rat adrenomedulary endothelial cells (RAMECs,…”
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Subcellular distribution of shear stress at the surface of flow-aligned and nonaligned endothelial monolayers by Barbee, K A, Mundel, T, Lal, R, Davies, P F

“…The stresses acting on the luminal surface of endothelial cells due to shear flow were determined on a subcellular scale. Atomic force microscopy was used to…”
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Shear Stress-Induced Reorganization of the Surface Topography of Living Endothelial Cells Imaged by Atomic Force Microscopy by Barbee, Kenneth A, Davies, Peter F, Lal, Ratneshwar

“…We report the first topographical data of the surface of living endothelial cells at sub-light-microscopic resolution, measurements essential for a detailed…”
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Real time monitoring of the effects of Heparan Sulfate Proteoglycan (HSPG) and surface charge on the cell adhesion process using thickness shear mode (TSM) sensor by Ergezen, E., Hong, S., Barbee, K.A., Lec, R.

“…The effects of Heparan Sulfate Proteoglycan (HSPG) and surface charge on the cellular interactions of the cell membrane with different substrates to determine…”
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Role of subcellular shear-stress distributions in endothelial cell mechanotransduction by Barbee, Kenneth A

“…The endothelium of blood vessels presents a wavy surface to the flowing blood. The subcellular distribution of shear stress depends on the shape and…”
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Programmable self-aligning ferrofluid masks for lithographic applications by Yellen, B.B., Friedman, G., Barbee, K.A.

“…A novel self-aligned "soft masking" method that is compatible with traditional photolithographic processes is demonstrated. This method uses a suspension of…”
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Ceramic-based multisite electrode arrays for chronic single-neuron recording by Moxon, K.A., Leiser, S.C., Gerhardt, G.A., Barbee, K.A., Chapin, J.K.

“…A method is described for the manufacture of a microelectrode array for chronic, multichannel, single neuron recording. The ceramic-based, multisite electrode…”
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Strain measurements in cultured vascular smooth muscle cells subjected to mechanical deformation by BARBEE, K. A, MACARAK, E. J, THIBAULT, L. E

“…Early work in the field of biomechanics employed rigorous application of the principles of mechanics to the study of the macroscopic structural response of…”
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An approach to targeted drug delivery based on uniform magnetic fields by Forbes, Z.G., Yellen, B.B., Barbee, K.A., Friedman, G.

“…The capability to deliver high effective dosages to specific sites in the human body has become the holy grail of drug delivery research. Drugs with proven…”
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Changes in surface topography in endothelial monolayers with time at confluence: influence on subcellular shear stress distribution due to flow by Barbee, K A

“…It is well known that the morphology of endothelial cells in culture changes dramatically as they go from subconfluence to confluence. After reaching…”
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Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction by Davies, P F, Barbee, K A, Volin, M V, Robotewskyj, A, Chen, J, Joseph, L, Griem, M L, Wernick, M N, Jacobs, E, Polacek, D C, dePaola, N, Barakat, A I

“…Blood flow interactions with the vascular endothelium represent a specialized example of mechanical regulation of cell function that has important…”
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In vitro cell shearing device to investigate the dynamic response of cells in a controlled hydrodynamic environment by Blackman, B R, Barbee, K A, Thibault, L E

“…Mechanical stresses and strains play important roles in the normal growth and development of biological tissues, yet the cellular mechanisms of…”
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Hemodynamics and atherogenesis. Endothelial surface dynamics in flow signal transduction by Davies, P F, Barbee, K A, Lal, R, Robotewskyj, A, Griem, M L

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An in vitro model of the tumor-lymphatic microenvironment with simultaneous transendothelial and luminal flows reveals mechanisms of flow enhanced invasionElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ib00085h by Pisano, M, Triacca, V, Barbee, K. A, Swartz, M. A

“…The most common cancers, including breast and skin, disseminate initially through the lymphatic system, yet the mechanisms by which tumor cells home towards,…”
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A mechanism for heterogeneous endothelial responses to flow in vivo and in vitro by Davies, Peter F., Mundel, Trevor, Barbee, Kenneth A.

“…Exposure of endothelium to a nominally uniform flow field in vivo and in vitro frequently results in a heterogeneous distribution of individual cell responses…”
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Quantification of beading intensity in cultured neurons by Dastgheyb, R M, Gallo, G, Barbee, K A

“…We present an implemented method for automated quantification of neuronal beading. Beading is the "morphological hallmark" of axonal injury and is present in…”
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Heterogeneous Cytoplasmic Calcium Response in Microvascular Endothelial Cells by Hong, D., Barbee, K.A., Buerk, D.G., Jaron, D.

“…We investigated changes in calcium concentration in response to the administration of ATP and the onset of shear stress with cultured rat adrenomedulary…”
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Deconvolution of Gel Filtration Chromatographs of Human Plasma Lipoproteins by Barbee, Kenneth A., Morrow, Julie A., Meredith, Stephen C.

“…Gel filtration chromatographs of lipoproteins represent a superposition, or convolution, of the intrinsic polydispersity of the solute and the dispersion due…”
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