Search Results - "Barbati, Zachary"
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The Role of PD-1 in Acute and Chronic Infection
Published in Frontiers in immunology (24-03-2020)“…PD-1 as an immune checkpoint molecule down-regulates T cell activity during immune responses in order to prevent autoimmune tissue damage. In chronic…”
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Knowledge and perceived competence with sexual and gender minority healthcare topics among medical students and medical school faculty
Published in BMC medical education (08-12-2023)“…Despite changes in social attitudes in the United States over the last decade, sexual and gender minority (SGM) individuals continue to face significant health…”
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Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins
Published in Cell reports (Cambridge) (01-05-2018)“…Selenof (15-kDa selenoprotein; Sep15) is an endoplasmic reticulum (ER)-resident thioredoxin-like oxidoreductase that occurs in a complex with…”
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How DNA Polymerase X Preferentially Accommodates Incoming dATP Opposite 8-Oxoguanine on the Template
Published in Biophysical journal (03-12-2013)“…The modified base 8-oxo-7,8-dihydro-2′-deoxyguanosine (oxoG) is a common DNA adduct produced by the oxidation of DNA by reactive oxygen species. Kinetic data…”
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Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria
Published in PloS one (25-07-2013)“…Intercellular adhesion molecule 1 (ICAM-1) is a membrane-bound glycoprotein expressed on endothelial cells and cells of the immune system. Human ICAM-1…”
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Shedding of Hepatitis C Virus in Semen of Human Immunodeficiency Virus-Infected Men
Published in Open forum infectious diseases (01-03-2016)“…HCV was shed into the semen of one-third of HIV-infected MSM with recent or chronic HCV infection. Levels were plausibly sufficient to transmit HCV during…”
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Models of conformational selection of DNA polymerase X in the presence of oxoG lesions help interpret kinetics data
Published in The FASEB journal (01-04-2013)“…Abstract only DNA polymerase X (pol X) from the African swine fever virus (ASFV) is a 174‐amino‐acid repair polymerase that participates in a viral Base…”
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Molecular dynamics studies of polymerase X/DNA complexes in the presence of OxoG on the templating strand
Published in The FASEB journal (01-04-2012)“…Abstract only The African Swine Fever Virus (ASFV) is an encapsulated deoxyvirus known to induce a lethal infection in domestic pigs. The double‐stranded DNA…”
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Conformational explorations into DNA polymerase X from African swine fever virus in the presence of oxoG lesions
Published in The FASEB journal (01-04-2011)“…Originating from the African swine fever virus, DNA polymerase X (pol X) is a 174‐amino‐acid, low fidelity repair polymerase that participates in viral Base…”
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The Role of the Selenoprotein Glutathione Peroxidase-1 in T Cell Activation and Differentiation
Published 01-01-2016“…Glutathione peroxidase-1 (GPx-1) is an antioxidant enzyme that plays an important role in reducing cellular oxidative stress. The expression of GPX1 has…”
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Dissertation -
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Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria. e69999
Published in PloS one (01-07-2013)“…Intercellular adhesion molecule 1 (ICAM-1) is a membrane-bound glycoprotein expressed on endothelial cells and cells of the immune system. Human ICAM-1…”
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Sofosbuvir in the treatment of early HCV infection in HIV-infected men
Published in HIV clinical trials (04-03-2017)“…There is an international epidemic of hepatitis C virus (HCV) infection among HIV-infected men who have sex with men. We previously showed that adding…”
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