Search Results - "Barbara H. Zimmermann"
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Pyrimidine Metabolism: Dynamic and Versatile Pathways in Pathogens and Cellular Development
Published in Journal of genetics and genomics (20-05-2015)“…The importance of pyrimidines lies in the fact that they are structural components of a broad spectrum of key molecules that participate in diverse cellular…”
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New Insights into rice pyrimidine catabolic enzymes
Published in Frontiers in plant science (01-02-2023)“…Rice is a primary global food source, and its production is affected by abiotic stress, caused by climate change and other factors. Recently, the pyrimidine…”
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Pyrimidine Pathway-Dependent and -Independent Functions of the Toxoplasma gondii Mitochondrial Dihydroorotate Dehydrogenase
Published in Infection and immunity (01-10-2016)“…Dihydroorotate dehydrogenase (DHODH) mediates the fourth step of de novo pyrimidine biosynthesis and is a proven drug target for inducing immunosuppression in…”
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Phytophthora infestans Dihydroorotate Dehydrogenase Is a Potential Target for Chemical Control - A Comparison With the Enzyme From Solanum tuberosum
Published in Frontiers in microbiology (28-06-2019)“…The oomycete is the causal agent of tomato and potato late blight, a disease that causes tremendous economic losses in the production of solanaceous crops. The…”
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A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii
Published in Frontiers in cellular and infection microbiology (22-03-2018)“…Cytidine triphosphate synthase catalyzes the synthesis of cytidine 5'-triphosphate (CTP) from uridine 5'-triphosphate (UTP), the final step in the production…”
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Hydrophilic Interaction Liquid Chromatography Coupled to Mass Spectrometry and Multivariate Analysis of the De Novo Pyrimidine Pathway Metabolites
Published in Biomolecules (Basel, Switzerland) (31-07-2019)“…In this study, we describe the optimization of a Hydrophilic Interaction Liquid Chromatography coupled to mass spectrometry (HILIC-MS) method for the…”
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Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase from Toxoplasma gondii
Published in Molecular and biochemical parasitology (01-08-2012)“…Toxoplasma gondii dihydroorotate dehydrogenase is an essential mitochondrial enzyme that exhibits inhibitor sensitivities distinct from those of the human and…”
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Cloning and expression of the dihydroorotate dehydrogenase from Toxoplasma gondii
Published in Biochimica et biophysica acta (20-03-2003)“…A full-length dihydroorotate dehydrogenase (DHODase) sequence was cloned from a Toxoplasma gondii tachyzoite cDNA library. The sequence was most similar to…”
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De novo pyrimidine biosynthesis in the oomycete plant pathogen Phytophthora infestans
Published in Gene (10-03-2014)“…The oomycete Phytophthora infestans, causal agent of the tomato and potato late blight, generates important economic and environmental losses worldwide. As…”
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Caracterización preliminar de compuestos antilisteriales producidos por bacterias ácido lácticas nativas
Published in Revista MVZ Córdoba (2008)“…Objetivo. Caracterizar los metabolitos producidos por bacterias ácido lácticas nativas con capacidad antilisterial. Materiales y métodos. Se analizaron 42…”
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Cloning and preliminary characterization of the dihydroorotase from Toxoplasma gondii
Published in Molecular and biochemical parasitology (01-07-2006)“…A full-length dihydroorotase (DHOase) sequence was cloned from a Toxoplasma gondii tachyzoite cDNA library. The sequence had a calculated molecular mass of…”
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Molecular cloning, recombinant expression and partial characterization of the aspartate transcarbamoylase from Toxoplasma gondii
Published in Molecular and biochemical parasitology (01-02-2002)“…A cDNA coding for a monofunctional aspartate transcarbamoylase (ATCase) was isolated from a Toxoplasma gondii tachyzoite cDNA library using a complementation…”
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Molecular Genetic and Protein Chemical Characterization of the Cytochrome ba3 from Thermus thermophilus HB8 (∗)
Published in The Journal of biological chemistry (01-09-1995)“…Thermus thermophilus HB8 cells grown under reduced dioxygen tensions contain a substantially increased amount of heme A, much of which appears to be due to the…”
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Characterization of the Pyrimidine Catabolic Pathway of Oryza sativa
Published in The FASEB journal (01-04-2018)“…Objective To characterize plant pyrimidine catabolic enzymes and to identify potential candidate for additional enzymes participating in the pathway Rice is a…”
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Recombinant Cry3Aa Has Insecticidal Activity against the Andean Potato Weevil, Premnotrypes vorax
Published in Biochemical and biophysical research communications (20-12-2000)“…The Andean potato weevil, Premnotrypes vorax, an insect of the order Coleoptera, is a major cause of damage to potato crops in the Andean regions of South…”
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Function of Conserved Histidine Residues in Mammalian Dihydroorotase
Published in Biochemistry (Easton) (30-05-1995)“…Dihydroorotase (DHOase, EC 3.5.2.3) catalyzes the reversible cyclization of carbamyl aspartate to form dihydroorotate, the third step in de novo pyrimidine…”
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Cloning, overexpression, and characterization of the functional dihydroorotase domain of the mammalian multifunctional protein CAD
Published in Biochemistry (Easton) (16-02-1993)“…Mammalian dihydroorotase (DHOase) is part of a large multidomain protein called CAD, which initiates the first three steps in the de novo pyrimidine…”
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Molecular Genetic and Protein Chemical Characterization of the Cytochrome ba from Thermus thermophilus HB8
Published in The Journal of biological chemistry (01-09-1995)“…Thermus thermophilus HB8 cells grown under reduced dioxygen tensions contain a substantially increased amount of heme A, much of which appears to be due to the…”
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