Search Results - "Barbalho, Geisa N"

Applying Different Conditions in the OphthalMimic Device Using Polymeric and Hydrogel-Based Hybrid Membranes to Evaluate Gels and Nanostructured Ophthalmic Formulations by Contarato, Jonad L A, Barbalho, Geisa N, Cunha-Filho, Marcilio, Gelfuso, Guilherme M, Gratieri, Tais

“…The OphthalMimic is a 3D-printed device that simulates human ocular conditions with artificial lacrimal flow, cul-de-sac area, moving eyelid, and a surface to…”
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Dynamic Ex Vivo Porcine Eye Model to Measure Ophthalmic Drug Penetration under Simulated Lacrimal Flow by Barbalho, Geisa N, Falcão, Manuel A, Lopes, Jefferson M. S, Lopes, Júlia M, Contarato, Jonad L. A, Gelfuso, Guilherme M, Cunha-Filho, Marcilio, Gratieri, Tais

“…Animal models are still used in the research and development of ophthalmic drug products, mainly due to the difficulty in simulating natural physiological…”
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In Vitro Performance Analysis of a Minoxidil Thermosensitive Gel with Reduced Runoff for Eyebrow Hair Growth by Xavier, Luciano C G, Matos, Breno N, Barbalho, Geisa N, Falcão, Manuel A, Cunha-Filho, Marcilio, Gelfuso, Guilherme M, Gratieri, Tais

“…There is a growing interest in innovative products for eyebrow hair loss treatment with fewer adverse effects. Nevertheless, a fundamental formulation aspect…”
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Hydrogel-based hybrid membrane enhances in vitro ophthalmic drug evaluation in the OphthalMimic device by Barbalho, Geisa N., Falcão, Manuel A., Amaral, Venâncio A., Contarato, Jonad L., Gelfuso, Guilherme M., Cunha-Filho, Marcilio, Gratieri, Tais

“…•The OphtalMimic device offers a precise simulation of human ocular conditions for improved ophthalmic drug product evaluation.•A novel hydrogel-based hybrid…”
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OphthalMimic: A new alternative apparatus without animal tissue for the evaluation of topical ophthalmic drug products by Barbalho, Geisa N., Falcão, Manuel A., Alves Amaral, Venâncio, Contarato, Jonad L.A., Barbalho, Aliucha M., Kaori Diógenes, Gabriela, Mariana Gomes Silva, Melyssa, Carvalho de Barros do Vale Rochelle, Beatriz, Gelfuso, Guilherme M., Cunha-Filho, Marcilio, Gratieri, Tais

“…•Novel in vitro methods are necessary to substitute costly, slow, and highly complexin vivomodels to evaluate ophthalmic formulations.•The efficacy of topical…”
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α-Cyclodextrin-based poly(pseudo)rotaxane for antifungal drug delivery to the vaginal mucosa by Costa, Rayssa H.F., Krawczyk-Santos, Anna Paula, Martins Andrade, Jayanaraian F., Barbalho, Geisa N., Almeida, Rosane M., Nóbrega, Yanna K.M., Cunha-Filho, Marcilio, Gelfuso, Guilherme M., Taveira, Stephânia F., Gratieri, Tais

“…This work aimed to evaluate poly(pseudo)rotaxanes (PPRs) potential for vaginal antifungal delivery. For this, PPRs containing terbinafine (TB) 2 % were…”
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In vitro skin model for the evaluation of burn healing drug delivery systems by Barbalho, Geisa N., Matos, Breno N., Espirito Santo, Maria Eduarda L., Silva, Vinicius R.C., Chaves, Sacha B., Gelfuso, Guilherme M., Cunha‐Filho, Marcilio, Gratieri, Taís

“…This study aims to develop an in vitro burnt skin model to be used in permeation experiments during the research and development of topical formulations for…”
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