Search Results - "Barbakadze, T."

Knockdown of interleukin-10 induces the redistribution of sigma1-receptor and increases the glutamate-dependent NADPH-oxidase activity in mouse brain neurons by Koriauli, S, Natsvlishvili, N, Barbakadze, T, Mikeladze, D

“…In the central nervous system, interleukin-10 (IL-10) provides trophic and survival effects directly on neurons, modulates neurite plasticity, and has a…”
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Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity by Zhuravliova, E., Barbakadze, T., Natsvlishvili, N., Mikeladze, D.G.

“…The NMDA receptor is believed to be important in a wide range of nervous system functions including neuronal migration, synapse formation, learning and memory…”
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Synaptic and Non-Synaptic Mitochondria in Hippocampus of Adult Rats Differ in Their Sensitivity to Hypothyroidism by Zhuravliova, E., Barbakadze, T., Jojua, N., Zaalishvili, E., Shanshiashvili, L., Natsvlishvili, N., Kalandadze, I., Narmania, N., Chogovadze, I., Mikeladze, D.

“…Hypothyroidism in humans provokes various neuropsychiatric disorders, movement, and cognitive abnormalities that may greatly depend on the mitochondrial energy…”
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W193 ANALYSIS OF CASE REPORTS OF PREGNANT WOMEN WITH RECURRENT PREGNANCY LOSSES by Janelidze, M., Barbakadze, T., Matitashvili, S., Pirtskhelani, N., Kochiashvili, N., Gambashidze, R.

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mGluR1 interacts with cystic fibrosis transmembrane conductance regulator and modulates the secretion of IL-10 in cystic fibrosis peripheral lymphocytes by Shanshiashvili, L.V., Dabrundashvili, N., Natsvlishvili, N., Kvaratskhelia, E., Zhuravliova, E., Barbakadze, T., Koriauli, S., Maisuradze, E., Topuria, T., Mikeladze, D.G.

“…► Production of IL-10 in normal lymphocytes is controlled by mGluR1. ► Diminished expression of mGluR1 in CF disarranges the secretion of IL-10. ►…”
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S-Nitrosylation Decreases the Adsorption of H-Ras in Lipid Bilayer and Changes Intrinsic Catalytic Activity by Shanshiashvili, L, Narmania, N, Barbakadze, T, Zhuravliova, E, Natsvlishvili, N, Ramsden, J, Mikeladze, D. G

“…Structural, chemical, and mutational studies have shown that C-terminal cysteine residues on H-Ras could potentially be oxidized by nitrosylation. For…”
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Hypoinsulinemia Alleviates the Grf1/Ras/Akt Anti-Apoptotic Pathway and Induces Alterations of Mitochondrial Ras Trafficking in Neuronal Cells by Zhuravliova, E., Barbakadze, T., Narmania, N., Sepashvili, M., Mikeladze, D. G.

“…Recent observations have established that interruption of insulin production causes deficits in learning and memory formation. We have studied the mechanism of…”
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P.1.c.013 Some molecular aspects of haloperidol's neurotoxicity by Zhuravliova, E, Barbakadze, T, Natsvlishvili, N, Mikeladze, D

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Inhibition of nitric oxide synthase and farnesyltransferase change the activities of several transcription factors by Zhuravliova, E, Barbakadze, T, Narmania, N, Ramsden, J, Mikeladze, D

“…Several types of cellular proteins can be modified by farnesylation and nitrosylation, of which the most significant is Ras. We used manumycin, a…”
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Ras proteins, nitrosylation and homocysteine metabolism by Mikeladze, D, Zhuravliova, E, Barbakadze, T

“…Elevated levels of homocysteine and S-adenosylmethionine are causal risk factors for several neurological disorders. Homocysteine is a sulfur-containing,…”
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Production of homocysteine in serum-starved apoptotic PC12 cells depends on the activation and modification of Ras by Barbakadze, T., Zhuravliova, E., Sepashvili, M., Zaalishvili, E., Ramsden, J.J., Bátor, J., Szeberényi, J., Mikeladze, D.

“…PC12 pheochromocytoma cells expressing a dominant inhibitory mutant of Ha-Ras (M-M17-26) and PC12 cells transfected with normal c-RasH (M-CR3B) have been used…”
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THE RELATIONSHIP BETWEEN FOLLICLE SIZE, OOCYTE MATURATION, BLASTOCYST FORMATION, BLASTOCYST PLOIDY, AND PREGNANCY OUTCOMES IN YOUNG WOMEN UNDERGOING IVF by Charkviani, T, Kristasashvili, J, Barbakadze, T, Gabadze, M, Kbilashvili, T, Makharadze, M

“…The relationship between follicle size, oocyte quality, and blastocyst ploidy is not fully established. This question becomes especially important for poor…”
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State of the endothelial system and expression of tissue hypoxia in children with bronchial asthma of atopic geneses by Barbakadze, T R, Garakanidze, I G, Mamuchishvili, I G, Tatulashvili, D R

“…In investigation were included 33 children with mild and moderate bronchial asthma of atopic geneses, average duration of the disease 3,5+/-1,9 years, average…”
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Social isolation in rats inhibits oxidative metabolism, decreases the content of mitochondrial K-Ras and activates mitochondrial hexokinase by Zhuravliova, Elene, Barbakadze, Tamar, Zaalishvili, Elnari, Chipashvili, Manana, Koshoridze, Nana, Mikeladze, David

“…Recent observations have suggested that Ras signaling includes combinations of extracellular-signal-regulated Ras activation at the plasma membrane and…”
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Synaptic and nonsynaptic mitochondria in hypothyroid conditions by Zhuravliova, E., Barbakadze, T., Shanshiashvili, L., Natsvlishvili, N., Zaalishvili, E., Kalandadze, I., Narmania, N., Chogovadze, I., Mikeladze, D.G.

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Creatine enhances survival of glutamate-treated neuronal/glial cells, modulates Ras/NF-κB signaling, and increases the generation of reactive oxygen species by Juravleva, Elena, Barbakadze, Tamar, Mikeladze, David, Kekelidze, Téa

“…The protective effects of creatine against glutamate cytotoxicity have been demonstrated in neuronal cells and animal models of neurodegenerative diseases. The…”
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Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity: Mechanisms of neurodegeneration by ZHURAVLIOVA, E, BARBAKADZE, T, NATSVLISHVILI, N, MIKELADZE, D. G

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Stratification of risk factors of progressing of acute respiratory infection in children by Mandzhavidze, N Sh, Zhorzholiani, L D, Barbakadze, T R, Gudzhabidze, R G, Kachkachishvili, M K

“…The work purpose is the complex estimation of endogenous intoxication (change of optical density of plasma and erythrocytes), depressions of tissue hypoxia and…”
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WITHDRAWN: Role of nitrosylaton and farnesylation in the regulation of homocysteine metabolism in PC12 cells by Zhuravliova, Elene I., Barbakadze, Tamar T., Sepashvili, Maia M., Khundadze, Mukhran N., Mikeladze, David G.

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WITHDRAWN: Role of nitrosylaton and farnesylation in the regulation of homocysteine metabolism in PC12 cells by Zhuravliova, Elene I, Barbakadze, Tamar T, Sepashvili, Maia M, Khundadze, Mukhran N, Mikeladze, David G

“…This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier…”
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