Search Results - "Barawkar, D A"

Synthesis of protected guanidinium linked dinucleoside incorporable into an oligonucleotide using solid phase DNA methodology by Barawkar, Dinesh A., Linkletter, Barry, Bruice, Thomas C.

“…The synthesis of novel fully protected guanidinium linked dinucleoside for incorporation into oligonucleotide using solid-phase DNA synthesis methodology was…”
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Triplex Formation at Physiological pH by 5-Me-dC-N4-(Spermine) [X] Oligodeoxynucleotides: Non Protonation of N3 in X of XG:C Triad and Effect of Base Mismatch/Ionic Strength on Triplex Stabilities by Barawkar, Dinesh A., Rajeev, Kallanthottathil G., Kumar, Vaijayanti A., Ganesh, Krishna N.

“…Oligodeoxynucleotide (ODN) directed triplex formation has therapeutic importance and depends on Hoogsteen hydrogen bonds between a duplex DNA and a third DNA…”
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Synthesis, Biophysical Properties, and Nuclease Resistance Properties of Mixed Backbone Oligodeoxynucleotides Containing Cationic Internucleoside Guanidinium Linkages: Deoxynucleic Guanidine/DNA Chimeras by Barawkar, Dinesh A., Bruice, Thomas C.

“…The synthesis of mixed backbone oligodeoxynucleotides (18-mers) consisting of positively charged guanidinium linkages along with negatively charged…”
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Fluorescent d(CGCGAATTCGCG): characterization of major groove polarity and study of minor groove interactions through a major groove semantophore conjugate by Barawkar, Dinesh A., Ganesh, Krishna N.

“…The major and minor groove in duplex DNA are sites of specific molecular recognition by DNA-binding agents such as proteins, drugs and metal complexes and have…”
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Enhancing DNA triplex stability via nucleobase modification by Ganesh, K. N., Kumar, Vaijayanti, Barawkar, D. A., Rajeev, K. G., Rana, V. S.

“…Abstract…”
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Triplex formation at physiological pH by oligonucleotides incorporating 5-Me-dC-(N4-spermine) by Barawkar, D A, Kumar, V A, Ganesh, K N

“…Oligonucleotide (ODN) directed triplex formation has therapeutic importance and depends on Hoogsteen hydrogen bonds between a duplex DNA and a third strand…”
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Exploring DNA minor groove interactions through a probe conjugate in major groove: fluorescence studies on netropsin complexation with dU-5-aminodansyl-DNA by Barawkar, D A, Ganesh, K N

“…The binding of netropsin to 5-Aminodansyl-dU-DNA (2-5) in minor groove is shown to correlate with fluorescence changes of dansyl fluorophore located in major…”
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Polarity Sensing by Fluorescent Oligonucleotides:  First Demonstration of Sequence-Dependent Microenvironmental Changes in the DNA Major Groove by Jadhav, Vasant R, Barawkar, Dinesh A, Ganesh, Krishna N

“…DNA duplex recognition by macromolecules (proteins, enzymes) and small molecules (drugs, metal complexes) occurs in the major or minor grooves of DNA via…”
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Deoxynucleic Guanidine/Peptide Nucleic Acid Chimeras:  Synthesis, Binding and Invasion Studies with DNA by Barawkar, Dinesh A, Kwok, Yan, Bruice, Thomas W, Bruice, Thomas C

“…A fully automated solid-phase synthetic procedure for incorporation of positively charged guanidinium linkages into otherwise neutral PNA sequences has been…”
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Deoxynucleic Guanidines/PNA (DNG/PNA) Chimeras:  Oligonucleoside Analogue Containing Cationic Guanidinium and Neutral Amide Linkages by Barawkar, Dinesh A, Bruice, Thomas C

“…Considerable attention has been paid to the modification of DNA and RNA to provide "oligonucleotides" with (i) sufficient binding at physiological temperature…”
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Molecular Recognition of 5-Amino-dU in the Central Strand of a DNA Triplex:  Formation of Triads AU#:A in Parallel and GU#:A in Antiparallel Motif by Rana, Vipul S, Barawkar, Dinesh A, Ganesh, Krishna N

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Triplex formation at physiological pH by 5-Me-dC-N super(4)-(spermine) [X] oligodeoxynucleotides: Non protonation of N3 in X of XG:C triad and effect of base mismatch/ionic strength on triplex stabilities by Barawkar, DA, Rajeev, K G, Kumar, V A, Ganesh, K N

“…Oligodeoxynucleotide (ODN) directed triplex formation has therapeutic importance and depends on Hoogsteen hydrogen bonds between a duplex DNA and a third DNA…”
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