Search Results - "Barathan, Muttiah"

The Profound Influence of Gut Microbiome and Extracellular Vesicles on Animal Health and Disease by Barathan, Muttiah, Ng, Sook Luan, Lokanathan, Yogeswaran, Ng, Min Hwei, Law, Jia Xian

“…The animal gut microbiota, comprising a diverse array of microorganisms, plays a pivotal role in shaping host health and physiology. This review explores the…”
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Innovative Strategies to Combat 5-Fluorouracil Resistance in Colorectal Cancer: The Role of Phytochemicals and Extracellular Vesicles by Barathan, Muttiah, Zulpa, Ahmad Khusairy, Ng, Sook Luan, Lokanathan, Yogeswaran, Ng, Min Hwei, Law, Jia Xian

“…Colorectal cancer (CRC) is a significant public health challenge, with 5-fluorouracil (5-FU) resistance being a major obstacle to effective treatment. Despite…”
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Milk-Derived Extracellular Vesicles: A Novel Perspective on Comparative Therapeutics and Targeted Nanocarrier Application by Barathan, Muttiah, Ng, Sook Luan, Lokanathan, Yogeswaran, Ng, Min Hwei, Law, Jia Xian

“…Milk-derived extracellular vesicles (mEVs) are emerging as promising therapeutic candidates due to their unique properties and versatile functions. These…”
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Unseen Weapons: Bacterial Extracellular Vesicles and the Spread of Antibiotic Resistance in Aquatic Environments by Barathan, Muttiah, Ng, Sook-Luan, Lokanathan, Yogeswaran, Ng, Min Hwei, Law, Jia Xian

“…This paper sheds light on the alarming issue of antibiotic resistance (ABR) in aquatic environments, exploring its detrimental effects on ecosystems and public…”
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Extracellular Vesicles in Breast Cancer: From Intercellular Communication to Therapeutic Opportunities by Muttiah, Barathan, Ng, Sook Luan, Lokanathan, Yogeswaran, Ng, Min Hwei, Law, Jia Xian

“…Breast cancer, a multifaceted and heterogeneous disease, poses significant challenges in terms of understanding its intricate resistance mechanisms and…”
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Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture by Barathan, Muttiah, Vellasamy, Kumutha Malar, Ibrahim, Zaridatul Aini, Mariappan, Vanitha, Hoong, See Mee, Vadivelu, Jamuna

“…To investigate the potential anti-breast cancer activity of zerumbone in regulating apoptotic mediators and cytokines in comparison with paclitaxel (positive…”
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Attrition of TCR Vα7.2+ CD161++ MAIT cells in HIV-tuberculosis co-infection is associated with elevated levels of PD-1 expression by Saeidi, Alireza, Tien Tien, Vicky L, Al-Batran, Rami, Al-Darraji, Haider A, Tan, Hong Y, Yong, Yean K, Ponnampalavanar, Sasheela, Barathan, Muttiah, Rukumani, Devi V, Ansari, Abdul W, Velu, Vijayakumar, Kamarulzaman, Adeeba, Larsson, Marie, Shankar, Esaki M

“…Mucosal-associated invariant T (MAIT) cells are evolutionarily conserved antimicrobial MR1-restricted CD8(+) T cells co-expressing the semi-invariant TCR…”
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Plant Defense Mechanisms against Polycyclic Aromatic Hydrocarbon Contamination: Insights into the Role of Extracellular Vesicles by Barathan, Muttiah, Ng, Sook Luan, Lokanathan, Yogeswaran, Ng, Min Hwei, Law, Jia Xian

“…Polycyclic aromatic hydrocarbons (PAHs) are persistent organic pollutants that pose significant environmental and health risks. These compounds originate from…”
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Extracellular Vesicles in Ovarian Cancer: From Chemoresistance Mediators to Therapeutic Vectors by Muttiah, Barathan, Muhammad Fuad, Nur Dina, Jaafar, Faizul, Abdullah, Nur Atiqah Haizum

“…Ovarian cancer (OC) remains the deadliest gynecological malignancy, with alarming projections indicating a 42% increase in new cases and a 51% rise in…”
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Beyond Blood Clotting: The Many Roles of Platelet-Derived Extracellular Vesicles by Muttiah, Barathan, Ng, Sook Luan, Lokanathan, Yogeswaran, Ng, Min Hwei, Law, Jia Xian

“…Platelet-derived extracellular vesicles (pEVs) are emerging as pivotal players in numerous physiological and pathological processes, extending beyond their…”
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Hijacking of the Host’s Immune Surveillance Radars by Burkholderia pseudomallei by Mariappan, Vanitha, Vellasamy, Kumutha Malar, Barathan, Muttiah, Girija, A. S. Smiline, Shankar, Esaki M., Vadivelu, Jamuna

“…Burkholderia pseudomallei ( B. pseudomallei ) causes melioidosis, a potentially fatal disease for which no licensed vaccine is available thus far. The…”
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A systematic scoping review of the multifaceted role of phoenixin in metabolism: insights from in vitro and in vivo studies by Muzammil, Adiba Najwa, Barathan, Muttiah, Yazid, Muhammad Dain, Sulaiman, Nadiah, Makpol, Suzana, Mohamed Ibrahim, Norlinah, Jaafar, Faizul, Abdullah, Nur Atiqah Haizum

“…Phoenixin (PNX) is an emerging neuropeptide that plays a significant role in regulating metabolism and reproduction. This comprehensive review examines…”
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Dentatin triggers ROS-mediated apoptosis, G0/G1 cell cycle arrest and release of Th1-related cytokines in colorectal carcinoma cells by Zulpa, Ahmad Khusairy, Muttiah, Barathan, Vellasamy, Kumutha Malar, Mariappan, Vanitha, Vadivelu, Jamuna

“…Naturally occurring carbazole alkaloid, Dentatin (DTN), is known to inhibit human cancer cell lines. However, it's inhibitory and immunomodulatory activities…”
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Small colony variants of Burkholderia pseudomallei : alteration of the virulence factors by Mariappan, Vanitha, Barathan, Muttiah, Zulpa, Ahmad Khusairy, Vadivelu, Jamuna, Vellasamy, Kumutha Malar

“…Burkholderia pseudomallei produce small colony variants (SCVs) that can persist in harsh conditions. This study aimed to compare SCV with B. pseudomallei…”
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Exploring Synergistic Effects of Bioprinted Extracellular Vesicles for Skin Regeneration by Taghdi, Manal Hussein, Muttiah, Barathan, Chan, Alvin Man Lung, Fauzi, Mh Busra, Law, Jia Xian, Lokanathan, Yogeswaran

“…Regenerative medicine represents a paradigm shift in healthcare, aiming to restore tissue and organ function through innovative therapeutic strategies. Among…”
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Hyperforin-mediated anticancer mechanisms in MDA-MB-231 cell line: insights into apoptotic mediator modulation and caspase activation by Barathan, Muttiah, Zulpa, Ahmad Khusairy, Vellasamy, Kumutha Malar, Ibrahim, Zaridatul Aini, Hoong, See Mee, Mariappan, Vanitha, Venkatraman, Gopinath, Vadivelu, Jamuna

“…Breast cancer has been recorded as a frequent malignant cancer. The side effects of current chemotherapy drugs are still a severe problem. Hence, naturally…”
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From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses by Barathan, Muttiah

“…Abstract Acute Undifferentiated Febrile Illness (AUFI) presents a clinical challenge, often characterized by sudden fever, non-specific symptoms, and potential…”
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Viral Persistence and Chronicity in Hepatitis C Virus Infection: Role of T-Cell Apoptosis, Senescence and Exhaustion by Barathan, Muttiah, Mohamed, Rosmawati, Yong, Yean K, Kannan, Meganathan, Vadivelu, Jamuna, Saeidi, Alireza, Larsson, Marie, Shankar, Esaki Muthu

“…Hepatitis C virus (HCV) represents a challenging global health threat to ~200 million infected individuals. Clinical data suggest that only ~10⁻15% of acutely…”
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Synergistic effect of hyperforin and paclitaxel on growth inhibition, apoptotic mediator activation in MCF-7 human breast cancer cells by Barathan, Muttiah, Zulpa, Ahmad Khusairy, Mee Hoong, See, Vellasamy, Kumutha Malar, Vadivelu, Jamuna

“…The role of hyperforin in combination anticancer therapy remain unknown. In this study, several doses of combination treatment (paclitaxel and hyperforin) were…”
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Anticancer effect of aromatic isoniazid derivatives in human gastric adenocarcinoma cells by Barathan, Muttiah, Shivashekaregowda, Naveen Kumar Hawala, Hoong, See Mee, Vellasamy, Kumutha Malar, Vadivelu, Jamuna

“…Current treatments for stomach cancer are often effective in curing cancer. However, these treatments can also have significant side effects, and they may not…”
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