Search Results - "Baranda, Sonia Jimenez"
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CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse
Published in Nature cell biology (01-11-2006)“…During physiological T-cell stimulation by antigen presenting cells (APCs), a major T-cell membrane rearrangement is known to occur leading to the organization…”
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2
Statins inhibit HIV-1 infection by down-regulating Rho activity
Published in The Journal of experimental medicine (16-08-2004)“…Human immunodeficiency virus (HIV)-1 infectivity requires actin-dependent clustering of host lipid raft-associated receptors, a process that might be linked to…”
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3
Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade
Published in Cancer immunology research (01-05-2014)“…The immunoregulatory protein T-cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates T-cell exhaustion and contributes to the…”
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4
Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α-producing and partially matured phenotype
Published in The Journal of clinical investigation (01-03-2011)“…Plasmacytoid DCs (pDCs) are innate immune cells that are specialized to produce IFN-α and to activate adaptive immune responses. Although IFN-α inhibits HIV-1…”
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5
Filamin-A regulates actin-dependent clustering of HIV receptors
Published in Nature cell biology (01-07-2007)“…Human immunodeficiency virus (HIV)-1 infection requires envelope (Env) glycoprotein gp120-induced clustering of CD4 and coreceptors (CCR5 or CXCR4) on the cell…”
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6
Oligonucleotide Motifs That Disappear during the Evolution of Influenza Virus in Humans Increase Alpha Interferon Secretion by Plasmacytoid Dendritic Cells
Published in Journal of Virology (01-04-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Dynamic Redistribution of Raft Domains as an Organizing Platform for Signaling during Cell Chemotaxis
Published in The Journal of cell biology (01-03-2004)“…Spatially restricted activation of signaling molecules governs critical aspects of cell migration; the mechanism by which this is achieved nonetheless remains…”
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8
Statins Induce Regulatory T Cell Recruitment via a CCL1 Dependent Pathway
Published in The Journal of immunology (1950) (01-09-2008)“…The statins, a group of inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase, are reported to influence a variety of immune system activities…”
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Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface
Published in Journal of cell science (01-04-2004)“…Association of matrix metalloprotease 9 (MMP9) to the cell membrane is considered important in tumor growth and angiogenesis. To dissect this regulatory…”
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10
CCR5 expression influences the progression of human breast cancer in a p53-dependent manner
Published in The Journal of experimental medicine (03-11-2003)“…Chemokines are implicated in tumor pathogenesis, although it is unclear whether they affect human cancer progression positively or negatively. We found that…”
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Specific SHP-2 Partitioning in Raft Domains Triggers Integrin-Mediated Signaling via Rho Activation
Published in The Journal of cell biology (15-04-2002)“…Cell signaling does not occur randomly over the cell surface, but is integrated within cholesterol-enriched membrane domains, termed rafts. By targeting SHP-2…”
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12
PTEN regulates motility but not directionality during leukocyte chemotaxis
Published in Journal of cell science (01-12-2004)“…The localization at opposite cell poles of phosphatidylinositol-3 kinases and PTEN (phosphatase and tensin homolog on chromosome 10) governs Dictyostelium…”
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13
Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains
Published in The Journal of experimental medicine (05-08-2002)“…Human immunodeficiency virus (HIV)-1 infection depends on multiple lateral interactions between the viral envelope and host cell receptors. Previous studies…”
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14
Filamin A interaction with the CXCR4 third intracellular loop regulates endocytosis and signaling of WT and WHIM-like receptors
Published in Blood (12-02-2015)“…Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a rare congenital immunodeficiency often caused by mutations in the last 10 to…”
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15
Segregation of Leading-Edge and Uropod Components into Specific Lipid Rafts during T Cell Polarization
Published in Proceedings of the National Academy of Sciences - PNAS (14-08-2001)“…Redistribution of specialized molecules in migrating cells develops asymmetry between two opposite cell poles, the leading edge and the uropod. We show that…”
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Plasmacytoid dendritic cells lead the charge against tumors
Published in The Journal of clinical investigation (01-02-2012)“…Imiquimod is a TLR agonist that is used as an antitumor agent, mainly against skin tumors. Its clinical benefits are well described in several studies;…”
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17
Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-Ordered Membrane Domains
Published in Chemistry & biology (30-07-2010)“…The lateral organization of lipids in cell membranes is thought to regulate numerous cell processes. Most studies focus on the coexistence of two fluid phases,…”
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Abstract 5410: Tim-3 expression and function in natural killer cells from metastatic melanoma patients
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…BACKGROUND: Tim-3 (T-cell immunoglobulin domain and mucin domain 3) is a type-I glycoprotein receptor with pivotal roles in immune regulation and tolerance…”
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19
Tim-3 expression and function in natural killer cells from advanced melanoma patients
Published in Journal of clinical oncology (20-05-2012)“…Abstract only 8571 Background: The concept of CD8 + T cell exhaustion in the context of metastatic cancer has been reinforced by the recent success of…”
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Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-[alpha]-producing and partially matured phenotype
Published in The Journal of clinical investigation (01-03-2011)“…Plasmacytoid DCs (pDCs) are innate immune cells that are specialized to produce IFN-α and to activate adaptive immune responses. Although IFN-α inhibits HIV-1…”
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