Search Results - "Barancík, Miroslav"

Quercetin improves postischemic recovery of heart function in doxorubicin-treated rats and prevents doxorubicin-induced matrix metalloproteinase-2 activation and apoptosis induction by Barteková, Monika, Šimončíková, Petra, Fogarassyová, Mária, Ivanová, Monika, Okruhlicová, Ľudmila, Tribulová, Narcisa, Dovinová, Ima, Barančík, Miroslav

“…Quercetin (QCT) is flavonoid that possesses various biological functions including anti-oxidative and radical-scavenging activities. Moreover, QCT exerts some…”
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New insight into p-glycoprotein as a drug target by Breier, Albert, Gibalova, Lenka, Seres, Mario, Barancik, Miroslav, Sulova, Zdenka

“…Multidrug resistance (MDR) of cancer tissue is a phenomenon in which cancer cells exhibit reduced sensitivity to a large group of unrelated drugs with…”
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Mechanisms Underlying Antiarrhythmic Properties of Cardioprotective Agents Impacting Inflammation and Oxidative Stress by Andelova, Katarina, Bacova, Barbara Szeiffova, Sykora, Matus, Hlivak, Peter, Barancik, Miroslav, Tribulova, Narcis

“…The prevention of cardiac life-threatening ventricular fibrillation and stroke-provoking atrial fibrillation remains a serious global clinical issue, with…”
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The Role of Heat Shock Proteins and Autophagy in Mechanisms Underlying Effects of Sulforaphane on Doxorubicin-Induced Toxicity in HEK293 Cells by Boťanská, B, Pecníková, V, Fogarassyová, M, Barančík, M

“…Doxorubicin (DOX) is a cytostatic agent belonging to anthracycline group. Important role in mechanism associated with negative effects of DOX plays an…”
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Oxidative Stress and Pathways of Molecular Hydrogen Effects in Medicine by Slezak, Jan, Kura, Branislav, LeBaron, Tyler W, Singal, Pawan K, Buday, Jozef, Barancik, Miroslav

“…There are many situations of excessive production of reactive oxygen species (ROS) such as radiation, ischemia/reperfusion (I/R), and inflammation. ROS…”
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Matrix Metalloproteinases and Their Role in Mechanisms Underlying Effects of Quercetin on Heart Function in Aged Zucker Diabetic Fatty Rats by Boťanská, Barbora, Barteková, Monika, Ferenczyová, Kristína, Fogarassyová, Mária, Kindernay, Lucia, Barančík, Miroslav

“…Several mechanisms may contribute to cardiovascular pathology associated with diabetes, including dysregulation of matrix metalloproteinases (MMPs). Quercetin…”
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The MEK/ERK Module Is Reprogrammed in Remodeling Adult Cardiomyocytes by Kubin, Thomas, Cetinkaya, Ayse, Kubin, Natalia, Bramlage, Peter, Sen-Hild, Bedriye, Gajawada, Praveen, Akintürk, Hakan, Schönburg, Markus, Schaper, Wolfgang, Choi, Yeong-Hoon, Barancik, Miroslav, Richter, Manfred

“…Fetal and hypertrophic remodeling are hallmarks of cardiac restructuring leading chronically to heart failure. Since the Ras/Raf/MEK/ERK cascade (MAPK) is…”
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The Interplay between Autophagy and Redox Signaling in Cardiovascular Diseases by Boťanská, Barbora, Dovinová, Ima, Barančík, Miroslav

“…Reactive oxygen and nitrogen species produced at low levels under normal cellular metabolism act as important signal molecules. However, at increased…”
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Helium Conditioning Increases Cardiac Fibroblast Migration Which Effect Is Not Propagated via Soluble Factors or Extracellular Vesicles by Jelemenský, Marek, Kovácsházi, Csenger, Ferenczyová, Kristína, Hofbauerová, Monika, Kiss, Bernadett, Pállinger, Éva, Kittel, Ágnes, Sayour, Viktor Nabil, Görbe, Anikó, Pelyhe, Csilla, Hambalkó, Szabolcs, Kindernay, Lucia, Barančík, Miroslav, Ferdinandy, Péter, Barteková, Monika, Giricz, Zoltán

“…Helium inhalation induces cardioprotection against ischemia/reperfusion injury, the cellular mechanism of which remains not fully elucidated. Extracellular…”
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Quercetin Exerts Age-Dependent Beneficial Effects on Blood Pressure and Vascular Function, But Is Inefficient in Preventing Myocardial Ischemia-Reperfusion Injury in Zucker Diabetic Fatty Rats by Ferenczyova, Kristina, Kalocayova, Barbora, Kindernay, Lucia, Jelemensky, Marek, Balis, Peter, Berenyiova, Andrea, Zemancikova, Anna, Farkasova, Veronika, Sykora, Matus, Tothova, Lubomira, Jasenovec, Tomas, Radosinska, Jana, Torok, Jozef, Cacanyiova, Sona, Barancik, Miroslav, Bartekova, Monika

“…: Quercetin (QCT) was shown to exert beneficial cardiovascular effects in young healthy animals. The aim of the present study was to determine cardiovascular…”
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Redox signaling in pathophysiology of hypertension by Majzunova, Miroslava, Dovinova, Ima, Barancik, Miroslav, Chan, Julie Y H

“…Reactive oxygen species (ROS) are products of normal cellular metabolism and derive from various sources in different cellular compartments. Oxidative stress…”
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Omega-3 Index and Anti-Arrhythmic Potential of Omega-3 PUFAs by Tribulova, Narcis, Szeiffova Bacova, Barbara, Egan Benova, Tamara, Knezl, Vladimir, Barancik, Miroslav, Slezak, Jan

“…Omega-3 polyunsaturated fatty acids (PUFAs), namely eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are permanent subjects of interest in relation…”
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Introduction by Barancík, Miroslav

“…Environmental factors including a high saturated fat and sucrose intake, sedentary life style and circadian rhythm disruption exert a major impact on the…”
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Age- and Phenotype-Dependent Changes in Circulating MMP-2 and MMP-9 Activities in Normotensive and Hypertensive Rats by Kollarova, Marta, Puzserova, Angelika, Balis, Peter, Radosinska, Dominika, Tothova, Lubomira, Bartekova, Monika, Barancik, Miroslav, Radosinska, Jana

“…Matrix metalloproteinases (MMPs) are important in the pathogenesis of numerous diseases. The present study aimed to monitor the activation of MMP-2 and MMP-9…”
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The Oak-wood Extract Robuvit ® Improves Recovery and Oxidative Stress after Hysterectomy: A Randomized, Double-blind, Placebo-controlled Pilot Study by Ferianec, Vladimír, Fülöp, Matej, Ježovičová, Miriam, Radošinská, Jana, Husseinová, Marta, Feriancová, Michaela, Radošinská, Dominika, Barančík, Miroslav, Muchová, Jana, Hȍgger, Petra, Ďuračková, Zdeňka

“…Hysterectomy has a variety of medical indications and improves pre-operative symptoms but might compromise the quality of life during recovery due to symptoms…”
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Suppression of β1-Adrenoceptor Autoantibodies is Involved in the Antiarrhythmic Effects of Omega-3 Fatty Acids in Male and Female Hypertensive Rats by Bacova, Barbara Szeiffova, Radosinska, Jana, Wallukat, Gerd, Barancik, Miroslav, Wallukat, Anne, Knezl, Vladimir, Sykora, Matus, Paulis, Ludovit, Tribulova, Narcis

“…The arrhythmogenic potential of β1-adrenoceptor autoantibodies (β1-AA), as well as antiarrhythmic properties of omega-3 in heart diseases, have been reported…”
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LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance by Barančík, Miroslav, Boháčová, Vierka, Sedlák, Ján, Sulová, Zdenka, Breier, Albert

“…The transmembrane transport pump P-glycoprotein (P-gp) causes the efflux of chemotherapeutic agents from cells and is an important system that secures…”
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Molecular and Cellular Mechanisms Associated with Effects of Molecular Hydrogen in Cardiovascular and Central Nervous Systems by Barancik, Miroslav, Kura, Branislav, LeBaron, Tyler W, Bolli, Roberto, Buday, Jozef, Slezak, Jan

“…The increased production of reactive oxygen species and oxidative stress are important factors contributing to the development of diseases of the…”
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P-glycoprotein--implications of metabolism of neoplastic cells and cancer therapy by Breier, Albert, Barancík, Miroslav, Sulová, Zdenka, Uhrík, Branislav

“…Multidrug resistance (MDR) of neoplastic tissues is a major obstacle in cancer chemotherapy. The predominant cause of MDR is the overexpression and drug…”
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ADMA, homocysteine and redox status improvement affected by 7-nitroindazole in spontaneously hypertensive rats by Dovinová, Ima, Hrabárová, Eva, Jansen, Eugene, Kvandová, Miroslava, Majzúnová, Miroslava, Berenyiová, Andrea, Barančík, Miroslav

“…Inhibition of nitric oxide (NO) production can influence blood pressure regulation and increase hypertension. Asymmetric dimethylarginine, ADMA, an analogue of…”
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