Search Results - "Baran, J S"

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    Correlation of aromatic hydroxylation of 11β-substituted estrogens with morphological transformation in vitro but not with in vivo tumor induction by these hormones by LIEHR, J. G, PURDY, R. H, BARAN, J. S, NUTTING, E. F, COLTON, F, RANDERATH, R, RANDERATH, K

    Published in Cancer research (Chicago, Ill.) (15-05-1987)
    “…In estrogen-induced cancer, catechol formation from administered steroids has been postulated to be a necessary event for estrogen activation and subsequent…”
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    A new class of orally active glycol renin inhibitors containing phenyllactic acid at P3 by Hanson, G J, Baran, J S, Lowrie, H S, Russell, M A, Sarussi, S J, Williams, K, Babler, M, Bittner, S E, Papaioannou, S E, Yang, P C

    “…We prepared a new series of renin inhibitors based on dipeptide glycols, replacing the P4-P3 subsites with an O-(N-morpholinocarbonyl)-3-L-phenyllactic acid…”
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    Enhanced potency dipeptide glycol renin inhibitors: studies in vitro and in the conscious rhesus by Hanson, G J, Baran, J S, Lowrie, H S, Sarussi, S J, Yang, P C, Babler, M, Bittner, S E, Papaioannou, S E, Walsh, G M

    “…We prepared a series of novel dipeptide amides of the formula Boc-Phe-Leu-X, where X is a 3-amino-3-alkyl-1,2-propanediol with lower alkyl substitutions at…”
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    Dipeptide glycols: a new class of renin inhibitors by Hanson, G J, Baran, J S, Lindberg, T, Walsh, G M, Papaioannou, S E, Babler, M, Bittner, S E, Yang, P C, Dal Corobbo, M

    “…The discovery of a new class of novel renin inhibitors consisting of protected dipeptide amides derived from aminoglycols (Formula I) prompted a study of…”
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    3-Alkyl-3-hydroxyglutaric Acids: A New Class of Hypocholesterolemic HMG CoA Reductase Inhibitors. 1 by Baran, John S, Laos, Ivar, Langford, Donna D, Miller, James E, Jett, Charlene, Taite, Beatrice, Rohrbacher, Elaine

    Published in Journal of medicinal chemistry (01-05-1985)
    “…Derivatives of 3-hydroxy-3-methylglutaric acid (HMG), a portion of the substrate for HMG CoA reductase, were prepared and tested for their inhibitory action…”
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    Synthesis and biological activities of arachidonic and alpha- and beta-alkyl-substituted arachidonic acid derivatives by Liang, C D, Baran, J S, Miller, J E, Steinman, D H, Saunders, R N

    “…In the male retired breeder rat, arachidonic acid 1a and 2,2-dimethylarachidonic acid 3a exhibited plasma platelet disaggregation as measured after 3 hr after…”
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