Search Results - "Barakat, Maxime"
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Treatment-resistant depression: Definitions, review of the evidence, and algorithmic approach
Published in Journal of affective disorders (01-03-2014)“…Abstract Background Most adults with major depressive disorder (MDD) fail to achieve remission with index pharmacological treatment. Moreover, at least half…”
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Extended-release naltrexone/bupropion is safe and effective among subjects with type 2 diabetes already taking incretin agents: a post-hoc analysis of the LIGHT trial
Published in International Journal of Obesity (01-08-2021)“…Background Extended-release naltrexone/bupropion (NB) is indicated for chronic weight management. Incretin agents are recommended for patients with type 2…”
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A randomized, placebo‐controlled study to evaluate safety and pharmacokinetics of inhaled ribavirin
Published in Clinical and translational science (01-09-2022)“…Ribavirin is an inosine monophosphate dehydrogenase inhibitor. Studies suggest ribavirin aerosol could be a safe and efficacious treatment option in the fight…”
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The relationship between early weight loss and weight loss maintenance with naltrexone-bupropion therapy
Published in EClinicalMedicine (01-07-2022)“…Extended-release (ER) naltrexone/bupropion (NB) was associated with greater weight loss than placebo in four randomized, 56-week trials. The association of NB…”
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Ribavirin aerosol in hospitalized adults with respiratory distress and COVID‐19: An open‐label trial
Published in Clinical and translational science (01-01-2023)“…There is an unmet medical need for effective treatments for hospitalized patients with coronavirus disease 2019 (COVID‐19). Ribavirin is a broad‐spectrum…”
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Clinico-Virological Outcomes and Mutational Profile of SARS-CoV-2 in Adults Treated with Ribavirin Aerosol for COVID-19 Pneumonia
Published in Microorganisms (Basel) (01-06-2024)“…The emergence of new SARS-CoV-2 variants can affect vaccine efficacy, laboratory diagnosis and the therapies already available, triggering interest in the…”
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Regional variability in Canadian routine care of type 2 diabetes, hypercholesterolemia, and hypertension: Results from the The Cardio-Vascular and metabolic treatments in Canada: Assessment of REal-life therapeutic value (CV-CARE) registry
Published in Journal of cardiology (01-10-2020)“…•Patient profiles and treatments for type 2 diabetes, hypercholesterolemia, and/or hypertension differ across Canada.•Variabilities in disease treatment…”
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Brodalumab success in patients with moderate-to-severe psoriasis who failed previous interleukin-17A inhibitors
Published in Journal of the American Academy of Dermatology (01-04-2021)Get full text
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Psychiatric Safety and Weight Loss Efficacy of Naltrexone/bupropion as Add-on to Antidepressant Therapy in Patients with Obesity or Overweight
Published in Journal of affective disorders (15-06-2021)“…•In patients with obesity / overweight who are taking antidepressants, extended-release naltrexone/bupropion (NB):•Appears to be safe;•Had significantly…”
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Extended‐release naltrexone/bupropion and liver health: Pooled, post hoc analysis from four randomized controlled trials
Published in Diabetes, obesity & metabolism (01-03-2021)“…Sustained weight loss improves liver histology in non‐alcoholic fatty liver disease. This post hoc analysis of four phase III, 56‐week, randomized controlled…”
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The generalized E-DVA method: a new approach for multi-modal pushover analysis under multi-component earthquakes with local variables maximization
Published in Bulletin of earthquake engineering (2024)“…Pushover analysis is a common nonlinear static procedure, performed to evaluate seismic response of civil structures. This approach allows considering the…”
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141-OR: Efficacy and Safety of Naltrexone/Bupropion as Add-On to Incretin Agents in Patients with Obesity and T2DM
Published in Diabetes (New York, N.Y.) (01-06-2020)“…There is significant overlap between obesity and type 2 diabetes (T2DM). Incretin agents (dipeptidyl peptidase 4 (DPP-4) inhibitors and glucagon-like peptide 1…”
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Real-world effectiveness of treatments for type 2 diabetes, hypercholesterolemia, and hypertension in Canadian routine care – Results from the CardioVascular and metabolic treatment in Canada: Assessment of REal-life therapeutic value (CV-CARE) registry, 12-months results
Published in Diabetes research and clinical practice (01-12-2020)“…•Achieving targets of cardiometabolic disease parameters crucial to delay complications.•RWE of the safety and efficacy of CV and metabolic drugs in Canada is…”
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Ribavirin Aerosol in the Treatment of SARS-CoV-2: A Case Series
Published in Infectious diseases and therapy (01-12-2021)“…Ribavirin is an inosine monophosphate dehydrogenase inhibitor with demonstrated activity against coronaviruses, including SARS-CoV-2. Five hospitalized…”
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Improving implementation of best practices in obesity management: Physician experiences in obesity care
Published in Clinical obesity (01-02-2024)“…Summary In this study, we sought to analyse experiences in weight management among physicians working in the area of obesity and contrast these experiences…”
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The i-ACT™ in Obesity educational intervention: a pilot study on improving Canadian family physician care in obesity medicine
Published in BMC family practice (02-05-2022)“…Obesity is a chronic problem in Canada and although the Canadian Medical Association recognizes obesity as a disease, health care professionals (HCPs) are not…”
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Real-World Effectiveness of Metformin-ER in Type 2 Diabetes Management From CV-CARE, a Canadian Registry
Published in Canadian journal of diabetes (01-10-2018)Get full text
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