Search Results - "Barajas, Brook"

A LncRNA-MAF:MAFB Transcription Factor Network Regulates Epidermal Differentiation by Lopez-Pajares, Vanessa, Qu, Kun, Zhang, Jiajing, Webster, Dan E., Barajas, Brook C., Siprashvili, Zurab, Zarnegar, Brian J., Boxer, Lisa D., Rios, Eon J., Tao, Shiying, Kretz, Markus, Khavari, Paul A.

“…Progenitor differentiation requires remodeling of genomic expression; however, in many tissues, such as epidermis, the spectrum of remodeled genes and the…”
Get full text

Lineage-specific dynamic and pre-established enhancer–promoter contacts cooperate in terminal differentiation by Rubin, Adam J, Barajas, Brook C, Furlan-Magaril, Mayra, Lopez-Pajares, Vanessa, Mumbach, Maxwell R, Howard, Imani, Kim, Daniel S, Boxer, Lisa D, Cairns, Jonathan, Spivakov, Mikhail, Wingett, Steven W, Shi, Minyi, Zhao, Zhixin, Greenleaf, William J, Kundaje, Anshul, Snyder, Michael, Chang, Howard Y, Fraser, Peter, Khavari, Paul A

“…Adam Rubin, Brook Barajas, Mayra Furlan-Magaril and colleagues studied dynamic chromatin across the genome of differentiating human skin keratinocytes,…”
Get full text

Identifying the assembly intermediate in which Gag first associates with unspliced HIV-1 RNA suggests a novel model for HIV-1 RNA packaging by Barajas, Brook C, Tanaka, Motoko, Robinson, Bridget A, Phuong, Daryl J, Chutiraka, Kasana, Reed, Jonathan C, Lingappa, Jaisri R

“…During immature capsid assembly, HIV-1 genome packaging is initiated when Gag first associates with unspliced HIV-1 RNA by a poorly understood process…”
Get full text

Formation of RNA Granule-Derived Capsid Assembly Intermediates Appears To Be Conserved between Human Immunodeficiency Virus Type 1 and the Nonprimate Lentivirus Feline Immunodeficiency Virus by Reed, Jonathan C, Westergreen, Nick, Barajas, Brook C, Ressler, Dylan T B, Phuong, Daryl J, Swain, John V, Lingappa, Vishwanath R, Lingappa, Jaisri R

“…During immature capsid assembly in cells, human immunodeficiency virus type 1 (HIV-1) Gag co-opts a host RNA granule, forming a pathway of intracellular…”
Get full text

106 Treatment with CC-99282 enhances antitumor function of the anti-CD19 CAR T cell therapy lisocabtagene maraleucel (liso-cel) by Brahmandam, Archana, Qin, Jim, Kim, Susan, Jiang, Yue, Barajas, Brook, Carrancio, Soraya, Peiser, Leanne

“…BackgroundLiso-cel, an autologous, CD19-directed, defined composition, 4-1BB CAR T cell product administered at equal target doses of CD8+ and CD4+ CAR+ T…”
Get full text

ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes by Boxer, Lisa D, Barajas, Brook, Tao, Shiying, Zhang, Jiajing, Khavari, Paul A

“…ZNF750 controls epithelial homeostasis by inhibiting progenitor genes while inducing differentiation genes, a role underscored by pathogenic ZNF750 mutations…”
Get full text

Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition by Webster, Dan E, Barajas, Brook, Bussat, Rose T, Yan, Karen J, Neela, Poornima H, Flockhart, Ross J, Kovalski, Joanna, Zehnder, Ashley, Khavari, Paul A

“…Thousands of putative enhancers are characterized in the human genome, yet few have been shown to have a functional role in cancer progression. Inhibiting…”
Get full text

Transcription Factors Regulate Enhancer-Promoter Contact Dynamics in Differentiation and Disease by Barajas, Brook Celia

“…Since the development of chromosome conformation capture (3C) by Job Dekker et al. in 2002, interrogation of enhancer-promoter interactions has led to an…”
Get full text