Search Results - "Baradaran, Behzad"
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The Different Mechanisms of Cancer Drug Resistance: A Brief Review
Published in Advanced pharmaceutical bulletin (01-09-2017)“…[...]the proteolysis of actin protein, and nuclear lamin proteins occurs in the external pathway and ultimately leads to cell apoptosis.32 In the internal…”
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miR‐193: A new weapon against cancer
Published in Journal of cellular physiology (01-10-2019)“…microRNAs (miRNAs) are known as a large group of short noncoding RNAs, which structurally consist of 19–22 nucleotides in length and functionally act as one of…”
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3
Myeloid‐derived suppressor cells: Important contributors to tumor progression and metastasis
Published in Journal of cellular physiology (01-04-2018)“…Myeloid‐derived suppressor cells (MDSCs) are traditionally considered among the major components of the immunosuppressive tumor microenvironment (TME)…”
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Regulatory mechanisms of miR-145 expression and the importance of its function in cancer metastasis
Published in Biomedicine & pharmacotherapy (01-01-2019)“…MicroRNAs are post-transcriptional mediators of gene expression and regulation, which play influential roles in tumorigenesis and cancer metastasis. The…”
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Promising approaches in cancer immunotherapy
Published in Immunobiology (1979) (01-03-2020)“…Immunotherapy is a promising field, which enhances and harnesses the powers of the host immune system against cancer and in recent years, has become a major…”
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Janus kinase inhibitors: A therapeutic strategy for cancer and autoimmune diseases
Published in Journal of cellular physiology (01-09-2020)“…Many cytokines are crucial drivers of cancers and autoimmune conditions. These proteins bind to receptors and signal their responses through Janus kinase (JAK)…”
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BACH1, the master regulator gene: A novel candidate target for cancer therapy
Published in Gene (15-08-2016)“…BACH1 (BTB and CNC homology 1, basic leucine zipper transcription factor 1) is a transcriptional factor and a member of cap ‘n’ collar (CNC) and basic region…”
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Molecular Mechanisms of Apoptosis and Roles in Cancer Development and Treatment
Published in Asian Pacific journal of cancer prevention : APJCP (03-04-2015)Get full text
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An Overview on SARS-CoV-2 (COVID-19) and Other Human Coronaviruses and Their Detection Capability via Amplification Assay, Chemical Sensing, Biosensing, Immunosensing, and Clinical Assays
Published in Nano-micro letters (2021)“…Highlights Various amplification assays and sensing can be applied for the detection of SARS-CoV-2. The outputs of biosensors should be presented…”
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The crucial role of ZEB2: From development to epithelial‐to‐mesenchymal transition and cancer complexity
Published in Journal of cellular physiology (01-09-2019)“…Zinc finger E‐box binding homeobox 2 (ZEB2) is a DNA‐binding transcription factor, which is mainly involved in epithelial‐to‐mesenchymal transition (EMT). EMT…”
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11
Comparison of DNA and mRNA vaccines against cancer
Published in Drug discovery today (01-03-2020)“…•Cancer vaccines have a long history, but traditional protein/peptide antigens have not had much success.•Nucleic acid vaccines based on either plasmid DNA or…”
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Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death
Published in Cancers (23-04-2020)“…Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is increasing the susceptibility of cells to death. Cancer cells…”
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Dysregulation of key microRNAs in pancreatic cancer development
Published in Biomedicine & pharmacotherapy (01-01-2019)“…The most important miRNAs that are dysregulated in PC initiation and development via specific targets, which modulate cell cycle and proliferation, apoptosis,…”
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Interplay between MAPK/ERK signaling pathway and MicroRNAs: A crucial mechanism regulating cancer cell metabolism and tumor progression
Published in Life sciences (1973) (01-08-2021)“…Mitogen-activated protein kinase (MAPK) signal transduction, as a highly conserved signaling pathway, is reported to be involved in various biological events,…”
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15
Targeting STAT3 in cancer and autoimmune diseases
Published in European journal of pharmacology (05-07-2020)“…Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that is activated downstream of a broad range of receptors particularly…”
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Cancer chemoresistance; biochemical and molecular aspects: a brief overview
Published in European journal of pharmaceutical sciences (30-06-2016)“…The effectiveness of chemotherapy is one of the main challenges in cancer treatment and resistance to classic drugs and traditional treatment processes is an…”
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The potential role of miR‐29 in health and cancer diagnosis, prognosis, and therapy
Published in Journal of cellular physiology (01-11-2019)“…miR‐29 family is one of the small noncoding RNAs and has a very important role in many physiologic and pathologic functions through regulating the target genes…”
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Herbal Medicine as Inducers of Apoptosis in Cancer Treatment
Published in Advanced pharmaceutical bulletin (01-10-2014)“…Cancer is uncontrolled growth of abnormal cells in the body. Nowadays, cancer is considered as a human tragedy and one of the most prevalent diseases in the…”
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Immune checkpoint blockade opens a new way to cancer immunotherapy
Published in Journal of cellular physiology (01-06-2019)“…Among the main promising systems to triggering therapeutic antitumor immunity is the blockade of immune checkpoints. Immune checkpoint pathways regulate the…”
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The paradox of Th17 cell functions in tumor immunity
Published in Cellular immunology (01-12-2017)“…•Th17 cells produce high level of IL-17 that have close association with tumorigenesis.•IL-17 cytokines are double-edged agents and depending on type of cancer…”
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