Search Results - "Barad, Omer"
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Biological Solution to a Fundamental Distributed Computing Problem
Published in Science (American Association for the Advancement of Science) (14-01-2011)“…Computational and biological systems are often distributed so that processors (cells) jointly solve a task, without any of them receiving all inputs or…”
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2
High-resolution genetic mapping of maize pan-genome sequence anchors
Published in Nature communications (16-04-2015)“…In addition to single-nucleotide polymorphisms, structural variation is abundant in many plant genomes. The structural variation across a species can be…”
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miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate
Published in Proceedings of the National Academy of Sciences - PNAS (07-09-2010)“…When stem cells and multipotent progenitors differentiate, they undergo fate restriction, enabling a single fate and blocking differentiation along alternative…”
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Identification of hundreds of conserved and nonconserved human microRNAs
Published in Nature genetics (01-07-2005)“…MicroRNAs are noncoding RNAs of ∼22 nucleotides that suppress translation of target genes by binding to their mRNA and thus have a central role in gene…”
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Sex-dependent dominance maintains migration supergene in rainbow trout
Published in Nature ecology & evolution (01-12-2019)“…Males and females often differ in their fitness optima for shared traits that have a shared genetic basis, leading to sexual conflict. Morphologically…”
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6
Error minimization in lateral inhibition circuits
Published in Science signaling (06-07-2010)“…The pattern of the sensory bristles in the fruit fly Drosophila is remarkably reproducible. Each bristle arises from a sensory organ precursor (SOP) cell that…”
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The Colorectal MicroRNAome
Published in Proceedings of the National Academy of Sciences - PNAS (07-03-2006)“…MicroRNAs (miRNAs) are a class of small noncoding RNAs that have important regulatory roles in multicellular organisms. The public miRNA database contains 321…”
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Robust selection of sensory organ precursors by the Notch–Delta pathway
Published in Current opinion in cell biology (01-12-2011)“…The patterning of multicellular organisms is robust to environmental, genetic, or stochastic fluctuations. Mathematical modeling is instrumental in identifying…”
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MicroRNA expression detected by oligonucleotide microarrays: system establishment and expression profiling in human tissues
Published in Genome research (01-12-2004)“…MicroRNAs (MIRs) are a novel group of conserved short approximately 22 nucleotide-long RNAs with important roles in regulating gene expression. We have…”
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MicroRNA expression patterns and function in endodermal differentiation of human embryonic stem cells
Published in PloS one (18-11-2008)“…microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs post-transcriptionally. Human embryonic stem cells (hESC), which exhibit the…”
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Publisher Correction: Sex-dependent dominance maintains migration supergene in rainbow trout
Published in Nature ecology & evolution (2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Design principle of gene expression used by human stem cells: implication for pluripotency
Published in The FASEB journal (01-01-2005)Get full text
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Draft Assembly of Elite Inbred Line PH207 Provides Insights into Genomic and Transcriptome Diversity in Maize
Published in The Plant cell (01-11-2016)“…Intense artificial selection over the last 100 years has produced elite maize (Zea mays) inbred lines that combine to produce high-yielding hybrids. To further…”
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Deciphering genetic factors that determine melon fruit‐quality traits using RNA‐Seq‐based high‐resolution QTL and eQTL mapping
Published in The Plant journal : for cell and molecular biology (01-04-2018)“…Summary Combined quantitative trait loci (QTL) and expression‐QTL (eQTL) mapping analysis was performed to identify genetic factors affecting melon (Cucumis…”
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Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing
Published in Nature biotechnology (01-02-2023)“…Here we introduce a mostly natural sequencing-by-synthesis (mnSBS) method for single-cell RNA sequencing (scRNA-seq), adapted to the Ultima genomics platform,…”
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Abstract 2946: Characterizing the genomic landscapes of breast and lung tumors using cost-effective whole genome sequencing
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Whole Genome Sequencing (WGS) has emerged as a pivotal tool for unraveling the intricate genomic alterations underlying cancer, enabling the detection…”
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Abstract 4926: Advancements in somatic variant calling from UG100 whole genome and whole exome sequencing data
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Somatic variant calling involves the identification of genomic alterations that occur in somatic cells, requiring deep coverage to enable high…”
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Efficiency and specificity in microRNA biogenesis
Published in Nature structural & molecular biology (01-06-2012)“…Primary microRNA cleavage by the Microprocessor complex comprising Drosha and DGCR8 needs to be specific yet efficient. Mathematical modeling complemented with…”
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Abstract 3134: Calling somatic variants from UG100 data using deep learning
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract UG100 is a novel next-generation sequencing platform that combines high throughput with significantly lower sequencing cost. Previous studies have…”
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Abstract 337: Balanced-strand sequencing for highly efficient duplex variant calling in circulating tumor DNA
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Several approaches for the detection of circulating tumor DNA (ctDNA) are anchored in the accurate identification of cancer-specific single nucleotide…”
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