Search Results - "Barabino, S M"

Mammalian nuclei contain foci which are highly enriched in components of the pre‐mRNA splicing machinery by Carmo‐Fonseca, M, Tollervey, D, Pepperkok, R, Barabino, S. M, Merdes, A, Brunner, C, Zamore, P. D, Green, M. R, Hurt, E, Lamond, A. I

“…The organization of the major snRNP particles in mammalian cell nuclei has been analysed by in situ labelling using snRNA‐specific antisense probes made of…”
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The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins by Barabino, S M, Hübner, W, Jenny, A, Minvielle-Sebastia, L, Keller, W

“…Cleavage and polyadenylation specificity factor (CPSF), a key component of the mammalian RNA 3'-end processing machinery, consists of four subunits of 160,…”
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Can a genetically-modified organism-containing diet influence embryo development? A preliminary study on pre-implantation mouse embryos by Cisterna, B, Flach, F, Vecchio, L, Barabino, S M L, Battistelli, S, Martin, T E, Malatesta, M, Biggiogera, M

“…In eukaryotic cells, pre-mRNAs undergo several transformation steps to generate mature mRNAs. Recent studies have demonstrated that a diet containing a…”
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Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly by Barabino, S M, Blencowe, B J, Ryder, U, Sproat, B S, Lamond, A I

“…HeLa cell nuclear splicing extracts have been prepared that are specifically and efficiently depleted of U1, U2, or U4/U6 snRNPs by antisense affinity…”
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Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing by Barabino, Silivia M.L., Sproat, Brian S., Lamond, Angus I.

“…Functional domains within the mammalian U2 snRNP particle that are required for pre-mRNA splicing have been analysed using antisense oligonucleotides. A…”
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Clinical and Biological Characteristics of Immunopathological Disease-related Erythema Nodosum in Children by P Picco, M Gattorno, S Vignola, A Barabino, M. G Marazzi, E Bondi, V Pistoia, A Buoncompagni

“…We report a series of 22 children with idiopathic, drug unrelated erythema nodosum (EN) admitted to our Department. In 5 of them an history of streptococcal…”
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Antisense affinity depletion of RNP particles. Application to spliceosomal snRNPs by Blencowe, B J, Barabino, S M

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Mapping U2 snRNP‐‐pre‐mRNA interactions using biotinylated oligonucleotides made of 2′‐OMe RNA by Barabino, S.M., Sproat, B.S., Ryder, U., Blencowe, B.J., Lamond, A.I.

“…Biotinylated 2′‐OMe RNA oligonucleotides complementary to two separate regions of human U2 snRNA have been used as affinity probes to study U2 snRNP‐‐pre‐mRNA…”
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Last but Not Least: Regulated Poly(A) Tail Formation by Barabino, Silvia M.L., Keller, Walter

“…Biogenesis of functional eukaryotic mRNAs requires the addition of a poly(A) tail at their 3' ends. The only known exceptions are the major histone mRNAs in…”
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Distinct roles of two Yth1p domains in 3′-end cleavage and polyadenylation of yeast pre-mRNAs by Barabino, Silvia M.L., Ohnacker, Martin, Keller, Walter

“…Yth1p is the yeast homologue of the 30 kDa subunit of mammalian cleavage and polyadenylation specificity factor (CPSF). The protein is part of the cleavage and…”
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WD-repeat protein Pfs2p bridges two essential factors within the yeast pre-mRNA 3'-end-processing complex by Ohnacker, M, Barabino, S.M.L, Preker, P.J, Keller, W

“…In the yeast Saccharomyces cerevisiae, pre‐mRNA 3′‐end processing requires six factors: cleavage factor IA (CF IA), cleavage factor IB (CF IB), cleavage factor…”
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Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs by Nemeroff, M E, Barabino, S M, Li, Y, Keller, W, Krug, R M

“…Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. Here, we demonstrate…”
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Inactivation of the zebrafish homologue of Chx10 by antisense oligonucleotides causes eye malformations similar to the ocular retardation phenotype by Barabino, Silvia M.L, Spada, Fabio, Cotelli, Franco, Boncinelli, Edoardo

“…We report the cloning of a zebrafish paired-type homeobox gene, Alx, closely related to the murine Chx10 and the gold fish Vsx-1 homeodomain proteins. Alx is…”
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Mammalian nuclei contain foci which are higly enriched in components of the pre-mRNA splicing machinery by CARMO-FONSECA, M, TOLLERVEY, D, PEPPERKOK, R, BARABINO, S. M. L, MERDES, A, BRUNNER, C, ZAMORE, P. D, GREEN, M. R, HURT, E, LAMOND, A. I

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