Search Results - "Barabino, M."
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The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation
Published in Nucleic acids research (21-07-2021)“…Abstract Liquid–liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such…”
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soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)
Published in The FASEB journal (01-10-2008)“…The receptor for advanced glycation endproducts (RAGE) mediates responses to cell danger and stress. When bound by its many ligands (which include advanced…”
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FUS-dependent liquid-liquid phase separation is important for DNA repair initiation
Published in The Journal of cell biology (03-05-2021)“…RNA-binding proteins (RBPs) are emerging as important effectors of the cellular DNA damage response (DDR). The RBP FUS is implicated in RNA metabolism and DNA…”
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SOX6 blocks the proliferation of BCR-ABL1+ and JAK2V617F+ leukemic cells
Published in Scientific reports (04-03-2019)“…SOX6 is a HMG-box transcription factor expressed in a wide range of tissues. Recent data show that SOX6 expression is altered in different cancers, in the…”
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RNA Splicing: A New Player in the DNA Damage Response
Published in International Journal of Cell Biology (2013)“…It is widely accepted that tumorigenesis is a multistep process characterized by the sequential accumulation of genetic alterations. However, the molecular…”
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Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2
Published in PloS one (16-04-2013)“…Paraquat (PQ) is a neurotoxic herbicide that induces superoxide formation. Although it is known that its toxic properties are linked to ROS production, the…”
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Proteomics Strategies to Identify SUMO Targets and Acceptor Sites: A Survey of RNA-Binding Proteins SUMOylation
Published in Neuromolecular medicine (01-12-2013)“…SUMOylation is a protein posttranslational modification that participates in the regulation of numerous biological processes within the cells. Small…”
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P0072 : Microinvasive intraoperative ultrasound pattern in predicting outcomes for single small (<3cm) hepatocellular carcinoma
Published in Journal of hepatology (01-04-2015)Get full text
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RNA-Binding Proteins in the Regulation of miRNA Activity: A Focus on Neuronal Functions
Published in Biomolecules (Basel, Switzerland) (30-09-2015)“…Posttranscriptional modifications of messenger RNAs (mRNAs) are key processes in the fine-tuning of cellular homeostasis. Two major actors in this scenario are…”
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Laparoscopic radiofrequency of hepatocellular carcinoma using ultrasound-guided selective intrahepatic vascular occlusion
Published in Surgical endoscopy (01-09-2008)“…Background The optimal treatment for hepatocellular carcinoma (HCC) is surgical resection. However, only a small percentage of patients are operative…”
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Impact of intraoperative ultrasonography in laparoscopic liver surgery
Published in Surgical endoscopy (01-02-2007)“…Laparoscopic surgery has gained growing acceptance, but this does not hold for laparoscopic surgery of the liver. This mainly includes diagnostic procedures,…”
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External validation of a simplified BCLC staging system for early hepatocellular carcinoma
Published in European journal of surgical oncology (01-08-2013)“…Abstract Background and aims The aim was to externally validate the capability of a simplified Barcelona Clinic Liver Cancer (s-BCLC) staging system in…”
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Neuronal RNA-binding proteins in health and disease
Published in Wiley interdisciplinary reviews. RNA (01-07-2014)“…In mammalian cells in general and in neurons in particular, mRNA maturation, translation, and degradation are highly complex and dynamic processes. RNA‐binding…”
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Laparoscopic Ablation Therapies For Hepatocellular Carcinoma: Indication, Technique And Long-Term Results
Published in HPB (Oxford, England) (01-04-2016)Get full text
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Microinvasive intraoperative ultrasound pattern in predicting outcomes for single small (<3 cm) hepatocellular carcinoma
Published in Digestive and liver disease (01-02-2014)Get full text
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Laparoscopic liver resections for hepatocellular carcinoma. Is it a feasible option for patients with liver cirrhosis?
Published in Langenbeck's archives of surgery (01-03-2009)“…Background Laparoscopic surgery has gained growing acceptance, but this does not hold for laparoscopic surgery of the liver, above all for patients with…”
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185 HEPATIC RESECTION FOR HEPATOCELLULAR CARCINOMA: VALIDATION OF SIMPLIFIED BCLC CLASSIFICATION
Published in Journal of hepatology (01-04-2012)Get full text
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Subnuclear localization and dynamics of the Pre-mRNA 3' end processing factor mammalian cleavage factor I 68-kDa subunit
Published in Molecular biology of the cell (01-04-2007)“…Mammalian cleavage factor I (CF Im) is an essential factor that is required for the first step in pre-mRNA 3' end processing. Here, we characterize CF Im68…”
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