Search Results - "Bar, P. R"

Willem Hendrik Gispen – An interview by Bär, P.R.

“…This text is based on three long interviews in Utrecht University′s Faculty Club, and on almost 40 years of working together in the same city, the same…”
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Neuroprotection by the Endogenous Cannabinoid Anandamide and Arvanil against In Vivo Excitotoxicity in the Rat: Role of Vanilloid Receptors and Lipoxygenases by Veldhuis, W. B, van der Stelt, M, Wadman, M. W, van Zadelhoff, G, Maccarrone, M, Fezza, F, Veldink, G. A, Vliegenthart, J. F. G, Bar, P. R, Nicolay, K, Marzo, V. Di

“…Type 1 vanilloid receptors (VR1) have been identified recently in the brain, in which they serve as yet primarily undetermined purposes. The endocannabinoid…”
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Exogenous Anandamide Protects Rat Brain against Acute Neuronal Injury In Vivo by van der Stelt, M, Veldhuis, W. B, van Haaften, G. W, Fezza, F, Bisogno, T, Bar, P. R, Veldink, G. A, Vliegenthart, J. F. G, Di Marzo, V, Nicolay, K

“…The endocannabinoid anandamide [N-arachidonoylethanolamine (AEA)] is thought to function as an endogenous protective factor of the brain against acute neuronal…”
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Reproducibility of measurements of cerebral infarct volume on CT scans by VAN DER WORP, H. B, CLAUS, S. P, BÄR, P. R, RAMOS, L. M. P, ALGRA, A, VAN GIJN, J, KAPPELLE, L. J

“…Infarct volume is increasingly used as an outcome measure in clinical trials of therapies for acute ischemic stroke. We tested which of 5 different methods to…”
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Collagen Containing Neurotrophin-3 (NT-3) Attracts Regrowing Injured Corticospinal Axons in the Adult Rat Spinal Cord and Promotes Partial Functional Recovery by Houweling, D.A., Lankhorst, A.J., Gispen, W.H., Bär, P.R., Joosten, E.A.J.

“…During development, neurotrophic factors play an important role in the guidance and outgrowth of axons. Our working hypothesis is that neurotrophic factors…”
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Sexual differences in onset of disease and response to exercise in a transgenic model of ALS by Veldink, J.H., Bär, P.R., Joosten, E.A.J., Otten, M., Wokke, J.H.J., van den Berg, L.H.

“…Transgenic mice that overexpress the mutant human SOD1 gene (hSOD1) serve as an animal model for amyotrophic lateral sclerosis (ALS). Age and sex are…”
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Progress testing with short answer questions by Rademakers, J., ten Cate, Th. J., Bär, P.R.

“…The concept of progress testing was developed in the 1970s. Significant features of progress tests are that the content is not linked to any specific course or…”
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Motor neuron disease in vitro: the use of cultured motor neurons to study amyotrophic lateral sclerosis by Bär, P.R

“…Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disease in which motor neurons in the nervous system die. The cause is unknown, and no…”
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The effect of tirilazad mesylate on infarct volume of patients with acute ischemic stroke by VAN DER WORP, H. B, KAPPELLE, L. J, ALGRA, A, BÄR, P. R, ORGOGOZO, J. M, RINGELSTEIN, E. B, BATH, P. M. W, VAN GIJN, J

“…The authors investigated whether the lack of effect of tirilazad on clinical outcome in patients with acute ischemic stroke is explained by failure of…”
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Intraspinal administration of an antibody against CD81 enhances functional recovery and tissue sparing after experimental spinal cord injury by Dijkstra, S., Duis, S., Pans, I.M., Lankhorst, A.J., Hamers, F.P.T., Veldman, H., Bär, P.R., Gispen, W.H., Joosten, E.A.J., Geisert, E.E.

“…We previously demonstrated that the tetraspanin protein CD81 is up-regulated by astrocytes and microglia after traumatic spinal cord injury in rats and that…”
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The time course of ischemic damage and cerebral perfusion in a rat model of space-occupying cerebral infarction by Hofmeijer, J, Veldhuis, W.B, Schepers, J, Nicolay, K, Kappelle, L.J, Bär, P.R, van der Worp, H.B

“…We aimed to establish a rat model of space-occupying hemispheric infarction to evaluate potential treatment strategies. For adequate timing of therapy in…”
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Delayed decompressive surgery increases apparent diffusion coefficient and improves peri-infarct perfusion in rats with space-occupying cerebral infarction by HOFMEIJER, J, SCHEPERS, J, VELDHUIS, W. B, NICOLAY, K, KAPPELLE, L. J, BÄR, P. R, VAN DER WORP, H. B

“…There is no conclusive experimental support that decompressive surgery in late stages of space-occupying cerebral infarction will improve outcome. We studied…”
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Ovariectomy and 17β-estradiol modulate disease progression of a mouse model of ALS by Groeneveld, G.J., Van Muiswinkel, F.L., Sturkenboom, J.M., Wokke, J.H.J., Bär, P.R., Van den Berg, L.H.

“…The incidence of amyotrophic lateral sclerosis (ALS) is higher among men than women but rises in women after the menopause. Estrogens may play a protective…”
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Chronic Mitochondrial Inhibition Induces Selective Motoneuron Death In Vitro: A New Model for Amyotrophic Lateral Sclerosis by Kaal, Evert C. A., Vlug, Angela S., Versleijen, Michelle W. J., Kuilman, Maja, Joosten, Elbert A. J., Bär, P. R. Dop

“…Evidence is increasing that mitochondrial dysfunction is involved in amyotrophic lateral sclerosis, a neurodegenerative disease characterized by selective…”
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Lesch–Nyhan disease and the basal ganglia by Visser, J.E, Bär, P.R, Jinnah, H.A

“…The purpose of this review is to summarize emerging evidence that the neurobehavioral features of Lesch–Nyhan disease (LND), a developmental disorder caused by…”
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Relations between muscle soreness and biochemical and functional outcomes of eccentric exercise by Rodenburg, J B, Bär, P R, De Boer, R W

“…Correlations between functional and biochemical outcomes of eccentric exercise and between these outcomes and "delayed-onset muscle soreness" (DOMS) were…”
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Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat by Houweling, D.A, van Asseldonk, J.T.H, Lankhorst, A.J, Hamers, F.P.T, Martin, D, Bär, P.R, Joosten, E.A.J

“…We studied the effect of local application of brain-derived neurotrophic factor (BDNF) on functional recovery after dorsal spinal cord transection in the adult…”
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Power density and exposure time of He-Ne laser irradiation are more important than total energy dose in photo-biomodulation of human fibroblasts in vitro by van Breugel, H H, Bär, P R

“…The absorption spectrum of human fibroblast monolayers showed several absorption peaks, among them one at a wave-length of 630 nm. Cultures of these…”
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Zinc amplifies mSOD1-mediated toxicity in a transgenic mouse model of amyotrophic lateral sclerosis by Groeneveld, G.J., de Leeuw van Weenen, J., van Muiswinkel, F.L., Veldman, H., Veldink, J.H., Wokke, J.H.J., Bär, P.R., van den Berg, L.H.

“…Transgenic mice overexpressing the human mutated form (G93A) of Cu,Zn-superoxide dismutase (mSOD1) develop motor neuron degeneration resembling amyotrophic…”
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Chronic idiopathic polyneuropathy presenting in middle or old age: a clinical and electrophysiological study of 75 patients by Notermans, N C, Wokke, J H, Franssen, H, van der Graaf, Y, Vermeulen, M, van den Berg, L H, Bär, P R, Jennekens, F G

“…The clinical and electrophysiological features were prospectively studied of 75 patients (46 men and 29 women) with chronic polyneuropathy presenting in middle…”
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