Search Results - "Baptista, Filipa"

Programming of future generations during breastfeeding: The intricate relation between metabolic and neurodevelopment disorders by Amaro, Andreia, Baptista, Filipa I., Matafome, Paulo

“…Lactation is a crucial postnatal programming window which can interfere with child development and predispose to metabolic disorders later in life, as insulin…”
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Tracing the influence of prenatal risk factors on the offspring retina: Focus on development and putative long‐term consequences by Baptista, Filipa I., Ambrósio, António F.

“…Background Pregnancy represents a window of vulnerability to fetal development. Disruptions in the prenatal environment during this crucial period can increase…”
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Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration by Socodato, Renato, Portugal, Camila C., Canedo, Teresa, Rodrigues, Artur, Almeida, Tiago O., Henriques, Joana F., Vaz, Sandra H., Magalhães, João, Silva, Cátia M., Baptista, Filipa I., Alves, Renata L., Coelho-Santos, Vanessa, Silva, Ana Paula, Paes-de-Carvalho, Roberto, Magalhães, Ana, Brakebusch, Cord, Sebastião, Ana M., Summavielle, Teresa, Ambrósio, António F., Relvas, João B.

“…Nervous tissue homeostasis requires the regulation of microglia activity. Using conditional gene targeting in mice, we demonstrate that genetic ablation of the…”
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Heme oxygenase-1 protects retinal endothelial cells against high glucose- and oxidative/nitrosative stress-induced toxicity by Castilho, Áurea F, Aveleira, Célia A, Leal, Ermelindo C, Simões, Núria F, Fernandes, Carolina R, Meirinhos, Rita I, Baptista, Filipa I, Ambrósio, António F

“…Diabetic retinopathy is a leading cause of visual loss and blindness, characterized by microvascular dysfunction. Hyperglycemia is considered the major…”
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The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer’s Disease: Critical Aspects to Unravel by Chiquita, Samuel, Rodrigues-Neves, Ana C., Baptista, Filipa I., Carecho, Rafael, Moreira, Paula I., Castelo-Branco, Miguel, Ambrósio, António F.

“…Alzheimer’s disease is the most frequent cause of dementia worldwide, representing a global health challenge, with a massive impact on the quality of life of…”
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Exploring the Role of Phenolic Compounds in Chronic Kidney Disease: A Systematic Review by Baptista, Filipa, Paié-Ribeiro, Jessica, Almeida, Mariana, Barros, Ana Novo

“…Chronic kidney disease (CKD) presents a formidable global health concern, affecting one in six adults over 25. This review explores the potential of phenolic…”
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Inside the Diabetic Brain: Role of Different Players Involved in Cognitive Decline by Gaspar, Joana M, Baptista, Filipa I, Macedo, M. Paula, Ambrósio, António F

“…Diabetes mellitus is the most common metabolic disease, and its prevalence is increasing. A growing body of evidence, both in animal models and epidemiological…”
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Sex‐specific changes in peripheral metabolism in a model of chronic anxiety induced by prenatal stress by Ferreira, Ana Sofia, Galvão, Sofia, Gaspar, Rita, Rodrigues‐Neves, Ana C., Ambrósio, António F., Matafome, Paulo, Gomes, Catarina A., Baptista, Filipa I.

“…Background Prenatal stress is associated with increased susceptibility to psychiatric and metabolic disorders later in life. Prenatal exposure to stress…”
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Resilience to stress and sex-specific remodeling of microglia and neuronal morphology in a rat model of anxiety and anhedonia by Gaspar, Rita, Soares-Cunha, Carina, Domingues, Ana Verónica, Coimbra, Bárbara, Baptista, Filipa I., Pinto, Luísa, Ambrósio, António F., Rodrigues, Ana João, Gomes, Catarina A.

“…Prenatal exposure to stress or glucocorticoids (GC) is associated with the appearance of psychiatric diseases later in life. Microglia, the immune cells of the…”
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Maternal diabetes affects rat offspring retinal structure and function: Sex-specific vulnerabilities at infancy by Realinho, Ana M., Boia, Raquel, Paiva, Beatriz, Correia, Raquel G., Gaspar, Rita, Ambrósio, António F., Baptista, Filipa I.

“…Maternal diabetes negatively impacts the offspring's brain, but little is known about its effects on the retina, which is also part of the central nervous…”
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Diabetes alters KIF1A and KIF5B motor proteins in the hippocampus by Baptista, Filipa I, Pinto, Maria J, Elvas, Filipe, Almeida, Ramiro D, Ambrósio, António F

“…Diabetes mellitus is the most common metabolic disorder in humans. Diabetic encephalopathy is characterized by cognitive and memory impairments, which have…”
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Sex-specificities in offspring neurodevelopment and behaviour upon maternal glycation: Putative underlying neurometabolic and synaptic changes by Amaro, Andreia, Sousa, Diana, Sá-Rocha, Mariana, Ferreira-Junior, Marcos D., Barra, Cátia, Monteiro, Tamaeh, Mathias, Paulo, Gomes, Rodrigo Mello, Baptista, Filipa I., Matafome, Paulo

“…Lactation is an important programming window for metabolic disease and neuronal alterations later in life. We aimed to study the effect of maternal glycation…”
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Flavonoids as Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer’s Disease by Baptista, Filipa I, Henriques, Ana G, Silva, Artur M. S, Wiltfang, Jens, da Cruz e Silva, Odete A. B

“…Alzheimer’s disease is characterized by pathological aggregation of protein tau and amyloid-β peptides, both of which are considered to be toxic to neurons…”
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Neonatal testosterone voids sexually differentiated microglia morphology and behavior by Simões-Henriques, Carla Filipa, Rodrigues-Neves, A Catarina, Sousa, Fábio J, Gaspar, Rita, Almeida, Inês, Baptista, Filipa I, Ambrósio, António F, Gomes, Catarina A

“…The involvement of immunity in psychiatric disorders, such as anxiety, is typified by the morphologic adaptation of microglia, immune cells of the brain, to…”
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Development of Emulsions Containing L-Ascorbic Acid and α-Tocopherol Based on the Polysaccharide FucoPol: Stability Evaluation and Rheological and Texture Assessment by Baptista, Sílvia, Baptista, Filipa, Freitas, Filomena

“…The main function of vitamin C, as an antioxidant, is to combat free radicals and prevent premature aging, smoothing wrinkles and expression lines. In…”
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High‐fat diet induces a neurometabolic state characterized by changes in glutamate and N‐acetylaspartate pools associated with early glucose intolerance: An in vivo multimodal MRI study by Ribeiro, Mário, Castelhano, João, Petrella, Lorena I., Sereno, José, Rodrigues, Tiago, Neves, Christian, Letra, Liliana, Baptista, Filipa I., Seiça, Raquel, Matafome, Paulo, Castelo‐Branco, Miguel

“…Background Type‐2 diabetes mellitus (T2DM) is a metabolic disorder with a broad range of complications in the brain that depend on the conditions that precede…”
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Unlocking the Potential of Spent Mushroom Substrate (SMS) for Enhanced Agricultural Sustainability: From Environmental Benefits to Poultry Nutrition by Baptista, Filipa, Almeida, Mariana, Paié-Ribeiro, Jéssica, Barros, Ana Novo, Rodrigues, Miguel

“…In this comprehensive review, we delve into the myriad applications of spent mushroom substrate (SMS) in agricultural contexts, with a particular emphasis on…”
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The Duration of Stress Determines Sex Specificities in the Vulnerability to Depression and in the Morphologic Remodeling of Neurons and Microglia by Gaspar, Rita, Soares-Cunha, Carina, Domingues, Ana Verónica, Coimbra, Bárbara, Baptista, Filipa I, Pinto, Luísa, Ambrósio, António F, Rodrigues, Ana João, Gomes, Catarina A

“…Stress exposure has been shown to induce a variety of molecular and functional alterations associated with anxiety and depression. Some studies suggest that…”
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Microglia cytoarchitecture in the brain of adenosine A2A receptor knockout mice: Brain region and sex specificities by Simões-Henriques, Carla, Mateus‐Pinheiro, Miguel, Gaspar, Rita, Pinheiro, Helena, Mendes Duarte, Joana, Baptista, Filipa I., Canas, Paula M., Fontes-Ribeiro, Carlos Alberto, Cunha, Rodrigo A., Ambrósio, António F., Gomes, Catarina A.

“…Microglia cells exert a critical role in brain development, mainly supported by their immune functions, which predicts an impact on the genesis of psychiatric…”
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Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance by Socodato, Renato, Almeida, Tiago O., Portugal, Camila C., Santos, Evelyn C.S., Tedim-Moreira, Joana, Galvão-Ferreira, João, Canedo, Teresa, Baptista, Filipa I., Magalhães, Ana, Ambrósio, António F., Brakebusch, Cord, Rubinstein, Boris, Moreira, Irina S., Summavielle, Teresa, Pinto, Inês Mendes, Relvas, João B.

“…Microglia, the largest population of brain immune cells, continuously interact with synapses to maintain brain homeostasis. In this study, we use conditional…”
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