Search Results - "Baptist Trimbos, J."
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A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer
Published in Clinical cancer research (15-06-2016)“…Completeness of cytoreductive surgery is a key prognostic factor for survival in patients with ovarian cancer. The ability to differentiate clearly between…”
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The Value of Intraoperative Near-Infrared Fluorescence Imaging Based on Enhanced Permeability and Retention of Indocyanine Green: Feasibility and False-Positives in Ovarian Cancer
Published in PloS one (25-06-2015)“…In ovarian cancer, two of the most important prognostic factors for survival are completeness of staging and completeness of cytoreductive surgery. Therefore,…”
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Self-reported sexual, bowel and bladder function in cervical cancer patients following different treatment modalities: longitudinal prospective cohort study
Published in International journal of gynecological cancer (01-11-2013)“…Conventional radical hysterectomy with pelvic lymphadenectomy (RHL) for early-stage cervical cancer is associated with significant bladder, anorectal, and…”
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4
HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+T lymphocytes
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2011)“…HLA-E is a nonclassical HLA class I molecule, which differs from classical HLA molecules by its nonpolymorphic, conserved nature. Expression and function of…”
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Intraepithelial macrophage infiltration is related to a high number of regulatory T cells and promotes a progressive course of HPV‐induced vulvar neoplasia
Published in International journal of cancer (15-02-2015)“…Human papilloma virus (HPV)‐induced usual‐type vulvar intraepithelial neoplasia (uVIN) is infiltrated by myeloid cells but the type and role of these cells is…”
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Randomized comparison of near-infrared fluorescence lymphatic tracers for sentinel lymph node mapping of cervical cancer
Published in Gynecologic oncology (01-10-2012)“…Abstract Objective Near-infrared fluorescence imaging using indocyanine green (ICG) has recently been introduced as a novel technique for sentinel lymph node…”
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Autocrine expression of the epidermal growth factor receptor ligand heparin-binding EGF-like growth factor in cervical cancer
Published in International journal of oncology (01-06-2017)“…In cervical cancer, the epidermal growth factor receptor (EGFR) is overexpressed in 70–90% of the cases and has been associated with poor prognosis. EGFR-based…”
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Potential use of lymph node-derived HPV-specific T cells for adoptive cell therapy of cervical cancer
Published in Cancer Immunology, Immunotherapy (01-12-2016)“…Adoptive transfer of tumor-specific T cells, expanded from tumor-infiltrating lymphocytes or from peripheral blood, is a promising immunotherapeutic approach…”
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Expression of coinhibitory receptors on T cells in the microenvironment of usual vulvar intraepithelial neoplasia is related to proinflammatory effector T cells and an increased recurrence‐free survival
Published in International journal of cancer (15-02-2015)“…Human papillomavirus‐induced usual‐type vulvar intraepithelial neoplasia (uVIN) are infiltrated by immune cells but apparently not cleared. A potential…”
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10
Noninvasive Detection of Metastases and Follicle Density in Ovarian Tissue Using Full-Field Optical Coherence Tomography
Published in Clinical cancer research (15-11-2016)“…Autotransplantation of ovarian tissue can be used to restore fertility in patients with cancer following gonadotoxic treatment. Whether this procedure is safe…”
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11
Molecular mechanisms of epidermal growth factor receptor overexpression in patients with cervical cancer
Published in Modern pathology (01-05-2011)“…The epidermal growth factor receptor is overexpressed in 70–90% of cervical cancers. Previously, we have shown that epidermal growth factor receptor…”
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Prevalence and Risk Factors of Ovarian Metastases in Breast Cancer Patients < 41 Years of Age in the Netherlands: A Nationwide Retrospective Cohort Study
Published in PloS one (26-01-2017)“…Breast cancer is one of the primary indications for cryopreservation and subsequent autotransplantation of ovarian tissue. The safety of this fertility…”
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13
Designing a high-throughput somatic mutation profiling panel specifically for gynaecological cancers
Published in PloS one (26-03-2014)“…Somatic mutations play a major role in tumour initiation and progression. The mutation status of a tumour may predict prognosis and guide targeted therapies…”
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Exploring Morphologic and Molecular Aspects of Endometrial Cancer Under Progesterone Treatment in the Context of Fertility Preservation
Published in International journal of gynecological cancer (01-03-2016)“…The standard treatment of early-stage (FIGO [International Federation of Gynecology and Obstetrics] I) endometrioid endometrial cancer (EEC) is hysterectomy…”
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15
Identification of cell-surface markers for detecting breast cancer cells in ovarian tissue
Published in Archives of gynecology and obstetrics (01-08-2016)“…Purpose The safety of ovarian tissue autotransplantation in oncology patients cannot be ensured, as current tumor-detection methods compromise the ovarian…”
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16
Loss of heterozygosity and copy number alterations in flow-sorted bulky cervical cancer
Published in PloS one (09-07-2013)“…Treatment choices for cervical cancer are primarily based on clinical FIGO stage and the post-operative evaluation of prognostic parameters including tumor…”
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High Human Papillomavirus Oncogene mRNA Expression and Not Viral DNA Load Is Associated with Poor Prognosis in Cervical Cancer Patients
Published in Clinical cancer research (01-01-2007)“…Purpose: Cervical cancer is now known to be caused by infection with an oncogenic type of the human papillomavirus (HPV). However, little is known about the…”
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18
Hysteroscopic Morcellator for Removal of Intrauterine Polyps and Myomas: A Randomized Controlled Pilot Study among Residents in Training
Published in Journal of minimally invasive gynecology (01-07-2008)“…Abstract The purpose of this randomized controlled study was to compare conventional resectoscopy and hysteroscopic morcellation among residents in training…”
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Lymph node sampling and taking of blind biopsies are important elements of the surgical staging of early ovarian cancer
Published in International journal of gynecological cancer (01-10-2010)“…The purpose of this study was to determine the effect of lymph node sampling and taking of blind biopsies as part of the surgical staging procedure for early…”
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Nerve-sparing radical hysterectomy: local recurrence rate, feasibility, and safety in cervical cancer patients stage IA to IIA
Published in International journal of gynecological cancer (01-01-2009)“…To clarify the debate about the possible threat of sparing the pelvic autonomic nerves in radical hysterectomy for cervical cancer to radicality, comparative…”
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