Search Results - "Baothman, Othman A"

The role of Gut Microbiota in the development of obesity and Diabetes by Baothman, Othman A, Zamzami, Mazin A, Taher, Ibrahim, Abubaker, Jehad, Abu-Farha, Mohamed

“…Obesity and its associated complications like type 2 diabetes (T2D) are reaching epidemic stages. Increased food intake and lack of exercise are two main…”
Get full text

Computational screening of natural compounds as putative quorum sensing inhibitors targeting drug resistance bacteria: Molecular docking and molecular dynamics simulations by Chaieb, Kamel, Kouidhi, Bochra, Hosawi, Salman Bakr, Baothman, Othman A.S., Zamzami, Mazin A., Altayeb, Hisham N.

“…Quorum sensing (QS) is a bacterial communication strategy controlling cells density, biofilm formation, virulence, sporulation, and survival. Since QS is…”
Get full text

Effect of atorvastatin on the gut microbiota of high fat diet-induced hypercholesterolemic rats by Khan, Tariq Jamal, Ahmed, Youssri M., Zamzami, Mazin A., Mohamed, Saleh A., Khan, Imran, Baothman, Othman A. S., Mehanna, Mohamed G., Yasir, Muhammad

“…The aim of the present study was to investigate alterations in gut microbiota associated with hypercholesterolemia and treatment with atorvastatin, a commonly…”
Get full text

Amelioration of CCl4-Induced Hepatotoxicity in Rabbits by Lepidium sativum Seeds by Abo-Golayel, Mohamed Kamel, Samy, Fatma, Baothman, Othman A., Zamzami, Mazin A.

“…The current study aimed to evaluate the probable protective effect of Lepidium sativum seeds (LSS) against CCl4 induced hepatic injury in New-Zealand rabbits…”
Get full text

Biodesulfurizing Microbes in the Petroleum Refinery Areas of Saudi Arabia by Ahmad, Abrar, Baothman, Othman A., Nadeem, Muhammad Shahid, Ahmad, Varish

“…Gordonia sp., Rhodococcus, Paenibaccilus, Mycobacterium and many other desulfurizing strains have shown good potential for dibenzothiophene (DBT), 4,…”
Get full text

In Silico Insights into the Arsenic Binding Mechanism Deploying Application of Computational Biology-Based Toolsets by Ahmad, Imran, Singh, Anil Kumar, Mohd, Shayan, Katari, Sudheer Kumar, Nalamolu, Ravina Madhulitha, Ahmad, Abrar, Baothman, Othman A., Hosawi, Salman A., Altayeb, Hisham, Nadeem, Muhammad Shahid, Ahmad, Varish

“…An assortment of environmental matrices includes arsenic (As) in its different oxidation states, which is often linked to concerns that pose a threat to public…”
Get full text

Pinocytosis as the Biological Mechanism That Protects Pgp Function in Multidrug Resistant Cancer Cells and in Blood–Brain Barrier Endothelial Cells by Omran, Ziad, Whitehouse, Chloe, Halwani, Majed, Zamzami, Mazin A., Baothman, Othman A., Rauch, Cyril

“…Cancer is the second leading cause of death worldwide. Chemotherapy has shown reasonable success in treating cancer. However, multidrug resistance (MDR), a…”
Get full text

Investigation of antioxidant and detoxifying capacities of some date cultivars (Phoenix dactylifera L.) irrigated with sewage water by Abdulaal, Wesam H, Zeyadi, Mustafa, Baothman, Othman A. S, Zamzami, Mazin A, Choudhry, Hani, Almulaiky, Yaaser Q, Saleh, Rashad M, Mohamed, Saleh A

“…The objective of the study was to compare the effect of irrigation by municipal water (MW) and sewage water (SW) on antioxidant and detoxifying capacities of…”
Get full text

Implications of Isoprostanes and Matrix Metalloproteinase-7 Having Potential Role in the Development of Colorectal Cancer in Males by Rasool, Mahmood, Malik, Arif, Ghuman, Ahmad Ashar, Ashraf, Muhammad Abdul Basit, Arooj, Mahwish, Waquar, Sulayman, Zahid, Sara, Shaheen, Sumera, Qazi, Aamer, Naseer, Muhammad Imran, Zamzami, Mazin A, Al-Ghafari, Ayat, Baothman, Othman A, Zeyadi, Mustafa, Helmi, Nawal, Choudhry, Hani, Jamal, Mohammad Sarwar, Al-Qahtani, Mohammed Hussein

“…Colorectal cancer (CRC) is the third most common type of cancer and leading cause of death worldwide. Major risk factors involved in the development of CRC are…”
Get full text

Exploring breast cancer treatment paradigms: innovative design, molecular docking and dynamic simulation of LOXL2 inhibitors by Baothman, Othman A., Islam, Md Rashedul

“…The impact of the LOXL2 enzyme on cell invasion and metastasis is significantly notable in breast cancer (BC), making it a promising therapeutic target in…”
Get full text

Characterization of Salmonella enterica serovar Typhimurium aconitase A by Baothman, Othman A S, Rolfe, Matthew D, Green, Jeffrey

“…Aconitases (Acn) are iron-sulfur proteins that catalyse the reversible isomerization of citrate and isocitrate via the intermediate cis-aconitate in the Krebs…”
Get full text

Identifying therapeutic antibacterial peptides against Vibrio cholerae to inhibit the function of Na(+)-translocating NADH-quinone reductase by Baothman, Othman A. S.

Get full text

Fabrication of an affordable and sensitive corticosteroid-binding globulin immunosensor based on electrodeposited gold nanoparticles modified glassy carbon electrode by Rabbani, Gulam, Ahmad, Abrar, Zamzami, Mazin A., Baothman, Othman A., Hosawi, Salman A., Altayeb, Hisham, Shahid Nadeem, Muhammad, Ahmad, Varish

“…[Display omitted] •GCE-AuNPs biosensor is fabricated for the detection of CBG.•The developed GCE-AuNPs biosensor exhibits high specificity with…”
Get full text

Thymoquinone-Induced Reactivation of Tumor Suppressor Genes in Cancer Cells Involves Epigenetic Mechanisms by Qadi, Shahad A, Hassan, Mohammed A, Sheikh, Ryan A, Baothman, Othman AS, Zamzami, Mazin A, Choudhry, Hani, Al-Malki, Abdulrahman Labeed, Albukhari, Ashwag, Alhosin, Mahmoud

“…The epigenetic silencing of tumor suppressor genes (TSGs) is a common finding in several solid and hematological tumors involving various epigenetic readers…”
Get full text

An affordable label-free ultrasensitive immunosensor based on gold nanoparticles deposited on glassy carbon electrode for the transferrin receptor detection by Ahmad, Abrar, Rabbani, Gulam, Zamzami, Mazin A., Hosawi, Salman, Baothman, Othman A., Altayeb, Hisham, Akhtar, Muhammad Shahid Nadeem, Ahmad, Varish, Khan, Mohsin Vahid, Khan, Mohammad Ehtisham, Kim, Se Hyun

“…In recent decades, there has been a concerning and consistent rise in the incidence of cancer, posing a significant threat to human health and overall quality…”
Get full text

Association of peptidyl prolyl cis/trans isomerase Rrd1 with C terminal domain of RNA polymerase II by Kashif, Mohd, Kumar, Bhupendra, Bharati, Akhilendra Pratap, Altayeb, Hisham, Asalam, Mohd, Akhtar, Mohd Sohail, Khan, Mohammad Imran, Ahmad, Abrar, Chaudhary, Hani, Hosawi, Salman Bakr, Zamzami, Mazin A., Baothman, Othman A.

“…The largest subunit of RNAPII extends as the conserved unstructured heptapeptide consensus repeats Y1S2P3T4S5P6S7 and their posttranslational modification,…”
Get full text

Atorvastatin Treatment Modulates the Gut Microbiota of the Hypercholesterolemic Patients by Khan, Tariq Jamal, Ahmed, Youssri M, Zamzami, Mazin A, Siddiqui, Aisha M, Khan, Imran, Baothman, Othman A S, Mehanna, Mohamed G, Kuerban, Abudukadeer, Kaleemuddin, Mohammed, Yasir, Muhammad

“…Hypercholesterolemia is one of the most important risk factors for development of cardiovascular diseases. The composition of gut microbiota (total microbes…”
Get more information

New paracetamol hybrids as anticancer and COX‐2 inhibitors: Synthesis, biological evaluation and docking studies by Alam, Mohammad Mahboob, Alsenani, Nawaf I., Abdelhamid, Antar A., Ahmad, Abrar, Baothman, Othman A., Hosawi, Salman A., Altayeb, Hisham, Nadeem, Mohammad Shahid, Ahmad, Varish, Nazreen, Syed, Elhenawy, Ahmed A.

“…Drug repurposing is an emerging field in drug development that has provided many successful drugs. In the current study, paracetamol, a known antipyretic and…”
Get full text

Potential antitumor activity of exopolysaccharide produced from date seed powder as a carbon source for Bacillus subtilis by Yousef, Rakan H., Baothman, Othman A.S., Abdulaal, Wesam H., Abo-Golayel, Mohamed K., Darwish, Anas A, Moselhy, Said S., Ahmed, Youssri M., Hakeem, Khalid Rehman

“…The major functions of Exopolysaccharide (EPS) include, preventing bacterial cells from desiccating and biofilm production to increase the colonization of…”
Get full text

Phytochemical analysis and nephroprotective potential of Ajwa date in doxorubicin‐induced nephrotoxicity rats: Biochemical and molecular docking approaches by Baothman, Othman A. S., Altayb, Hisham N., Zeyadi, Mustafa A., Hosawi, Salman B., Abo‐Golayel, Mohamed Kamel

“…The purpose of this study is to evaluate the likely defensive impact of Ajwa date aqueous extract (AJDAE) in alleviating the nephrotoxicity generated by…”
Get full text