Search Results - "Bao, Yifeng"
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A novel bi-level programming model for structure sustainability optimization of passenger transport corridor
Published in PloS one (08-07-2022)“…The transportation industry has entered a new stage from quantity expanding to structure optimization, quality and efficiency improvement, and from respective…”
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Soluble monomeric human programmed cell death-ligand 1 inhibits the functions of activated T cells
Published in Frontiers in immunology (17-05-2023)“…The presence of soluble human programmed cell death-ligand 1 (shPD-L1) in the blood of patients with cancer has been reported to be negatively correlated with…”
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High‐affinity PD‐1 molecules deliver improved interaction with PD‐L1 and PD‐L2
Published in Cancer science (01-08-2018)“…The inhibitory checkpoint molecule programmed death (PD)‐1 plays a vital role in maintaining immune homeostasis upon binding to its ligands, PD‐L1 and PD‐L2…”
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Regulation of Glioma Cells Migration by DYRK2
Published in Neurochemical research (01-11-2017)“…Dual-specificity tyrosine-regulated kinase 2 (DYRK2), a protein kinase that phosphorylates its substrates on serine/threonine, is expressed in numerous human…”
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In vivo therapeutic effects of affinity-improved-TCR engineered T-cells on HBV-related hepatocellular carcinoma
Published in Journal for immunotherapy of cancer (01-12-2020)“…BackgroundIn patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), virus-specific cytotoxic T lymphocytes (CTLs) fail to eliminate HCC…”
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Preoperative Hematologic Inflammatory Markers as Prognostic Factors in Patients with Glioma
Published in World neurosurgery (01-11-2018)“…Hematologic inflammatory markers are simple, inexpensive prognostic markers for various conditions. The prognostic significance of the neutrophil-to-lymphocyte…”
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Hydrophobic core evolution of major histocompatibility complex class I chain-related protein A for dramatic enhancing binding affinity
Published in International journal of biological macromolecules (01-06-2024)“…Interface residues at sites of protein–protein interaction (PPI) are the focus for affinity optimisation. However, protein hydrophobic cores (HCs) play…”
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High Expression of Pirh2 is Associated with Poor Prognosis in Glioma
Published in Cellular and molecular neurobiology (01-11-2017)“…p53-induced protein with a RING-H2 domain (Pirh2), also known as Rchy1, is an ubiquitin E3 ligase that regulates the turnover and functionality of several…”
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High-affinity human PD-L1 variants attenuate the suppression of T cell activation
Published in Oncotarget (24-10-2017)“…The activated T cells can be suppressed by programed death-1 (PD-1) axis through low affinity interaction between PD-1 and PD-ligand 1 (PD-L1) in solution or…”
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High-affinity human programmed death-1 ligand-1 variant promotes redirected T cells to kill tumor cells
Published in Cancer letters (10-04-2019)“…Tumor cells can escape immune surveillance through the programmed cell death protein 1 (PD-1) axis suppressing T cells. However, we recently demonstrated that…”
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High-affinity T cell receptors redirect cytokine-activated T cells (CAT) to kill cancer cells
Published in Frontiers of medicine (01-02-2019)“…Cytokine-activated T cells (CATs) can be easily expanded and are widely applied to cancer immunotherapy. However, the good efficacy of CATs is rarely reported…”
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ImmTAC/Anti‐PD‐1 antibody combination to enhance killing of cancer cells by reversing regulatory T‐cell‐mediated immunosuppression
Published in Immunology (01-10-2018)“…Summary Recently, bi‐functional molecules that can redirect immune effectors to tumour cells have emerged as potentially robust mediators of tumour regression…”
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Transcriptome alterations and therapeutic drugs in different organs after spinal cord injury based on integrated bioinformatic analysis
Published in Journal of Neurorestoratology (01-06-2023)“…To identify transcriptomic alterations and therapeutic drugs in different organs after spinal cord injury via comprehensive bioinformatics analyses…”
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Whole‐exome sequencing revealed mutational profiles of giant cell glioblastomas
Published in Brain pathology (Zurich, Switzerland) (01-11-2019)“…Giant cell glioblastoma (gcGBM) is a rare histological variant of GBM, accounting for about 1% of all GBM. The prognosis is poor generally though gcGBM does…”
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Imm TAC /Anti‐ PD ‐1 antibody combination to enhance killing of cancer cells by reversing regulatory T‐cell‐mediated immunosuppression
Published in Immunology (01-10-2018)“…Summary Recently, bi‐functional molecules that can redirect immune effectors to tumour cells have emerged as potentially robust mediators of tumour regression…”
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Up-regulation of Vps4A promotes neuronal apoptosis after intracerebral hemorrhage in adult rats
Published in Metabolic brain disease (01-04-2017)“…Vps4, vacuolar protein sorting 4, belongs to ATPases Associated with diverse cellular Activities (AAA) protein family which is made up of Vps4A and Vps4B…”
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The Expression of NP847 and Sox2 after TBI and Its Influence on NSCs
Published in Frontiers in cellular neuroscience (22-12-2016)“…The proliferation and differentiation of neural stem cells (NSCs) is important for neural regeneration after cerebral injury. Here, for the first time, we show…”
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