Search Results - "Banu, Matei A"
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Induction of synthetic lethality in IDH1-mutated gliomas through inhibition of Bcl-xL
Published in Nature communications (20-10-2017)“…Certain gliomas often harbor a mutation in the activity center of IDH1 (R132H), which leads to the production of the oncometabolite 2-R-2-hydroxyglutarate…”
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2
Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states
Published in Nature communications (04-05-2023)“…Glioblastoma (GBM) diffusely infiltrates the brain and intermingles with non-neoplastic brain cells, including astrocytes, neurons and microglia/myeloid cells…”
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Endoscope-assisted endonasal versus supraorbital keyhole resection of olfactory groove meningiomas: comparison and combination of 2 minimally invasive approaches
Published in Journal of neurosurgery (01-03-2016)“…Although the endonasal endoscopic approach has been applied to remove olfactory groove meningiomas, controversy exists regarding the efficacy and safety of…”
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4
Rationale and Clinical Implications of Fluorescein-Guided Supramarginal Resection in Newly Diagnosed High-Grade Glioma
Published in Frontiers in oncology (26-05-2021)“…Current standard of care for glioblastoma is surgical resection followed by temozolomide chemotherapy and radiation. Recent studies have demonstrated that >95%…”
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Endoscopic Endonasal Resection of Suprasellar Meningiomas: The Importance of Case Selection and Experience in Determining Extent of Resection, Visual Improvement, and Complications
Published in World neurosurgery (01-09-2014)“…Objective Suprasellar meningiomas have been resected via various open cranial approaches. During the past 2 decades, the endoscopic endonasal approach has been…”
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6
Ex vivo multi-electrode analysis reveals spatiotemporal dynamics of ictal behavior at the infiltrated margin of glioma
Published in Neurobiology of disease (01-02-2020)“…The purpose of this study is to develop a platform in which the cellular and molecular underpinnings of chronic focal neocortical lesional epilepsy can be…”
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Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo
Published in Oncotarget (15-03-2016)“…It remains a challenge in oncology to identify novel drug regimens to efficiently tackle glioblastoma, the most common primary brain tumor in adults. Here, we…”
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Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling
Published in Journal of neuro-oncology (01-01-2015)“…Malignant gliomas represent one of the most aggressive forms of cancer, displaying high mortality rates and limited treatment options. Specific subpopulations…”
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9
Thoracic low grade glial neoplasm with concurrent H3 K27M and PTPN11 mutations
Published in Acta neuropathologica communications (28-04-2022)“…We present the case of a 41-year-old man who developed worsening mid-thoracic back pain and imaging revealed a well-circumscribed intramedullary tumor in the…”
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10
Low-dose intrathecal fluorescein and etiology-based graft choice in endoscopic endonasal closure of CSF leaks
Published in Clinical neurology and neurosurgery (01-01-2014)“…Abstract Objective Skull base cerebrospinal fluid (CSF) leaks of various etiologies are increasingly repaired through the natural corridor using an endoscopic…”
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Synchronous supratentorial and infratentorial oligodendrogliomas with incongruous IDH1 mutations, a case report
Published in Acta neuropathologica communications (29-09-2021)“…Infratentorial oligodendrogliomas, a rare pathological entity, are generally considered metastatic lesions from supratentorial primary tumors. Here, we report…”
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Maximizing Extent of Resection for Noneloquent Glioblastoma: Fluorescent Dye or Intraoperative Magnetic Resonance Imaging?
Published in Journal of clinical oncology (20-12-2023)Get full text
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13
COVID-19 neuropathology at Columbia University Irving Medical Center/New York Presbyterian Hospital
Published in Brain (London, England : 1878) (15-04-2021)“…Many patients with SARS-CoV-2 infection develop neurological signs and symptoms, though, to date, little evidence exists that primary infection of the brain is…”
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Endoscopic endonasal approach for suprasellar meningiomas: introduction of a new scoring system to predict extent of resection and assist in case selection with long-term outcome data
Published in Journal of neurosurgery (01-07-2021)“…The endoscopic endonasal approach (EEA) has gained increasing popularity for the resection of suprasellar meningiomas (SSMs). Appropriate case selection is…”
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Endonasal endoscopic transsphenoidal resection of intrinsic third ventricular craniopharyngioma: surgical results
Published in Journal of neurosurgery (01-10-2019)“…Intrinsic third ventricular craniopharyngiomas (IVCs) have been reported by some authors to "pose the greatest surgical challenge" of all craniopharyngiomas…”
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16
Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma
Published in Cell reports (Cambridge) (28-05-2024)“…Glioblastoma (GBM) is a deadly brain tumor, and the kinesin motor KIF11 is an attractive therapeutic target with roles in proliferation and invasion…”
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Single-cell analysis of 5-aminolevulinic acid intraoperative labeling specificity for glioblastoma
Published in Journal of neurosurgery (01-04-2024)“…Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor, and resection is a key part of the standard of care. In fluorescence-guided…”
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Pneumocephalus patterns following endonasal endoscopic skull base surgery as predictors of postoperative CSF leaks
Published in Journal of neurosurgery (01-10-2014)“…Postoperative pneumocephalus is a common occurrence after endoscopic endonasal skull base surgery (ESBS). The risk of cerebrospinal fluid (CSF) leaks can be…”
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Sensitivity and specificity of intrathecal fluorescein and white light excitation for detecting intraoperative cerebrospinal fluid leak in endoscopic skull base surgery: a prospective study
Published in Journal of neurosurgery (01-03-2016)“…The intraoperative detection of CSF leaks during endonasal endoscopic skull base surgery is critical to preventing postoperative CSF leaks. Intrathecal…”
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Decision-making algorithm for minimally invasive approaches to anterior skull base meningiomas
Published in Neurosurgical focus (01-04-2018)“…OBJECTIVE Anterior skull base meningiomas are benign lesions that cause neurological symptoms through mass effect on adjacent neurovascular structures. While…”
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