Search Results - "Bansal, Ruby"

Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids by Sebastian, Rebecca, Jin, Kang, Pavon, Narciso, Bansal, Ruby, Potter, Andrew, Song, Yoonjae, Babu, Juliana, Gabriel, Rafael, Sun, Yubing, Aronow, Bruce, Pak, ChangHui

“…De novo mutations and copy number deletions in NRXN1 (2p16.3) pose a significant risk for schizophrenia (SCZ). It is unclear how NRXN1 deletions impact…”
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A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance to Amphotericin B by Bansal, Ruby, Sen, Shib Sankar, Muthuswami, Rohini, Madhubala, Rentala

“…Leishmania donovani is a protozoan parasite, a primary causative agent of visceral leishmaniasis. Sterol produced via the mevalonate pathway, show differences…”
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Individual Polychlorinated Biphenyl (PCB) Congeners Produce Tissue- and Gene-Specific Effects on Thyroid Hormone Signaling during Development by Giera, Stefanie, Bansal, Ruby, Ortiz-Toro, Theresa M, Taub, Daniel G, Zoeller, R. Thomas

“…Polychlorinated biphenyls (PCB) are industrial chemicals linked to developmental deficits that may be caused in part by disrupting thyroid hormone (TH) action…”
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Bioreducible polyethylenimine nanoparticles for the efficient delivery of nucleic acids by Bansal, Ruby, Tayal, Shweta, Gupta, K C, Kumar, Pradeep

“…Recently, non-viral vectors for nucleic acid delivery have received considerable attention. Among the various non-viral vectors, branched polyethylenimine…”
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Polychlorinated Biphenyls 105 and 118 Form Thyroid Hormone Receptor Agonists after Cytochrome P4501A1 Activation in Rat Pituitary GH3 Cells by Gauger, Kelly J., Stefanie Giera, David S. Sharlin, Bansal, Ruby, Eric Iannacone, Zoeller, R. Thomas

“…Background: Polychlorinated biphenyls (PCBs) may interfere with thyroid hormone (TH) signaling by reducing TH levels in blood, by exerting direct effects on TH…”
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Thyroid Hormone, Brain Development, and the Environment by Zoeller, R. Thomas, Amy L. S. Dowling, Carolyn T. A. Herzig, Iannacone, Eric A., Gauger, Kelly J., Bansal, Ruby

“…Thyroid hormone is essential for normal brain development. Therefore, it is a genuine concern that thyroid function can be altered by a very large number of…”
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4-Hydroxy-PCB106 acts as a direct thyroid hormone receptor agonist in rat GH3 cells by You, Seo-Hee, Gauger, Kelly J., Bansal, Ruby, Zoeller, R. Thomas

“…Polychlorinated biphenyls (PCBs) may interfere with thyroid hormone (TH) action by interacting directly with the TH receptor (TR). We found that the…”
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CLARITY-BPA: Bisphenol A or Propylthiouracil on Thyroid Function and Effects in the Developing Male and Female Rat Brain by Bansal, Ruby, Zoeller, R Thomas

“…Abstract The CLARITY-BPA experiment, a large collaboration between the National Institute of Environmental Health Sciences, the National Toxicology Program,…”
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Stigmasterol as a potential biomarker for amphotericin B resistance in Leishmania donovani by Bansal, Ruby, Sen, Shib Sankar, Muthuswami, Rohini, Madhubala, Rentala

“…Abstract Background Leishmania donovani, a protozoan parasite, is the primary causative agent for visceral leishmaniasis. Toxicity and increased resistance to…”
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Engineered polymeric amphiphiles self-assembling into nanostructures and acting as efficient gene and drug carriers by Bansal, Ruby, Kumar, Pradeep

“…Nonviral gene delivery systems are finding widespread use due to their safety, rapid and economical production, and ease of modification. In this work, series…”
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Bisphenol S Alters the Lactating Mammary Gland and Nursing Behaviors in Mice Exposed During Pregnancy and Lactation by LaPlante, Charlotte D, Catanese, Mary C, Bansal, Ruby, Vandenberg, Laura N

“…High doses of estrogenic pharmaceuticals were once prescribed to women to halt lactation. Yet, the effects of low-level xenoestrogens on lactation remain…”
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Maternal thyroid hormone increases HES expression in the fetal rat brain: An effect mimicked by exposure to a mixture of polychlorinated biphenyls (PCBs) by Bansal, Ruby, You, Seo-Hee, Herzig, Carolyn T.A., Zoeller, R. Thomas

“…Thyroid hormone is known to be essential for normal brain development both before and after birth, but much less is known about the role of thyroid hormone…”
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Cuscuta reflexa Possess Potent Inhibitory Activity Against Human Malaria Parasite: An In Vitro and In Vivo Study by Ojha, Sashi Bhusan, Sah, Raj Kumar, Madan, Evanka, Bansal, Ruby, Roy, Shaktirekha, Singh, Shailja, Dhangadamajhi, Gunanidhi

“…Drug resistance to practically all antimalarial drugs in use necessitate the development of new chemotherapeutics against malaria. In this aspect,…”
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A9997 Hypertension and low estimated Glomerular Filtration rate (eGFR) - Screening for CKD Risk factor by Kumar, Anish, Bansal, Ruby, Sarkar, Taposh, Singh, Narinder Pal

“…OBJECTIVES:To study the prevalence of major CKD risk factors such as hypertension (HTN), Diabetes Mellitus (DM), obesity and also to find-out prevalence of low…”
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pH responsive dextran nanoparticles loaded with doxorubicin and RITA against cancer cells: synergistic inhibitory effects by Bhatnagar, Priyanka, Bansal, Ruby, Vishwakarma, Vishal K., Yadav, Harlokesh N., Dinda, Amit K., Gupta, Yogender K.

“…Cancer is the second leading cause of death globally. Despite of significant advances in combination therapy of chemotherapeutic drugs, its application in…”
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Bisphenol-A, an Environmental Contaminant that Acts as a Thyroid Hormone Receptor Antagonist in Vitro, Increases Serum Thyroxine, and Alters RC3/Neurogranin Expression in the Developing Rat Brain by Zoeller, R. Thomas, Bansal, Ruby, Parris, Colleen

“…Considering the importance of thyroid hormone (TH) in brain development, it is of potential concern that a wide variety of environmental chemicals can…”
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Biodegradable and versatile polyethylenimine derivatives efficiently transfer DNA and siRNA into mammalian cells by Bansal, Ruby, Gupta, Kailash C., Kumar, Pradeep

“…Two new non-toxic and biodegradable polymers, TEPA@bPEI (TBP) and TEPA@lPEI (TLP), are synthesized, which efficiently deliver nucleic acids in vitro…”
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Comparative Analyses of the 12 Most Abundant PCB Congeners Detected in Human Maternal Serum for Activity at the Thyroid Hormone Receptor and Ryanodine Receptor by Sethi, Sunjay, Morgan, Rhianna K, Feng, Wei, Lin, Yanping, Li, Xueshu, Luna, Corey, Koch, Madison, Bansal, Ruby, Duffel, Michael W, Puschner, Birgit, Zoeller, R. Thomas, Lehmler, Hans-Joachim, Pessah, Isaac N, Lein, Pamela J

“…Polychlorinated biphenyls (PCBs) pose significant risk to the developing human brain; however, mechanisms of PCB developmental neurotoxicity (DNT) remain…”
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A correlation of thermodynamic parameters with size of copper-chelated albumin aggregates by Bansal, Ruby, Pattanayek, Sudip K., Bansal, Rohit, Rathore, Anurag S.

“…Protein conformations are strictly related to its biological function, and the variation in the structure has a major impact on human health. Metal ions are…”
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Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: A dynamic and kinetic evaluation of a putative mode-of-action by Paul, Katie B, Hedge, Joan M, Bansal, Ruby, Zoeller, R. Thomas, Peter, Robert, DeVito, Michael J, Crofton, Kevin M

“…Abstract This work tests the mode-of-action (MOA) hypothesis that maternal and developmental triclosan (TCS) exposure decreases circulating thyroxine (T4)…”
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