Search Results - "Bannister, Kirsty"

The plasticity of descending controls in pain: translational probing by Bannister, Kirsty, Dickenson, A. H.

“…Descending controls, comprising pathways that originate in midbrain and brainstem regions and project onto the spinal cord, have long been recognised as key…”
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Multiple sites and actions of gabapentin-induced relief of ongoing experimental neuropathic pain by Bannister, Kirsty, Qu, Chaoling, Navratilova, Edita, Oyarzo, Janice, Xie, Jennifer Yanhua, King, Tamara, Dickenson, Anthony H., Porreca, Frank

“…Gabapentin (GBP) is a first-line therapy for neuropathic pain, but its mechanisms and sites of action remain uncertain. We investigated GBP-induced modulation…”
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Selective modulation of tonic aversive qualities of neuropathic pain by morphine in the central nucleus of the amygdala requires endogenous opioid signaling in the anterior cingulate cortex by Navratilova, Edita, Nation, Kelsey, Remeniuk, Bethany, Neugebauer, Volker, Bannister, Kirsty, Dickenson, Anthony H., Porreca, Frank

“…The amygdala is a key subcortical region believed to contribute to emotional components of pain. As opioid receptors are found in both the central (CeA) and…”
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Monoaminergic mediation of hyperalgesic and analgesic descending control of nociception in mice by Nemoto, Wataru, Kozak, Dalia, Sotocinal, Susana G., Tansley, Shannon, Bannister, Kirsty, Mogil, Jeffrey S.

“…Descending control of nociception (DCN; also known as conditioned pain modulation [CPM], the behavioral correlate of diffuse noxious inhibitory controls) is…”
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The impact of paradigm and stringent analysis parameters on measuring a net conditioned pain modulation effect: A test, retest, control study by Cummins, Tatum M., McMahon, Stephen B., Bannister, Kirsty

“…Background Reporting in conditioned pain modulation (CPM) studies is not standardised. Here, two CPM protocols were performed in populations of healthy human…”
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Morphine effects within the rodent anterior cingulate cortex and rostral ventromedial medulla reveal separable modulation of affective and sensory qualities of acute or chronic pain by Gomtsian, Lusine, Bannister, Kirsty, Eyde, Nathan, Robles, Dagoberto, Dickenson, Anthony H., Porreca, Frank, Navratilova, Edita

“…Modulation of pain may result from engagement of opioid receptors in multiple brain regions. Whether sensory and affective qualities of pain are differentially…”
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The association between psychosocial factors and mental health symptoms in cervical spine pain with or without radiculopathy on health outcomes: a systematic review by Mansfield, Michael, Thacker, Mick, Taylor, Joseph L, Bannister, Kirsty, Spahr, Nicolas, Jong, Stephanie T, Smith, Toby

“…Neck pain, with or without radiculopathy, can have significant negative effects on physical and mental wellbeing. Mental health symptoms are known to worsen…”
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Irritable bowel syndrome in inflammatory bowel disease: Distinct, intertwined, or unhelpful? Views and experiences of patients by Huisman, Danielle, Sweeney, Louise, Bannister, Kirsty, Moss-Morris, Rona

“…The aim of the study was to explore beliefs about pain and related coping strategies of individuals experiencing abdominal pain during remitted inflammatory…”
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Mu-opioid and noradrenergic α2-adrenoceptor contributions to the effects of tapentadol on spinal electrophysiological measures of nociception in nerve-injured rats by Bee, Lucy A., Bannister, Kirsty, Rahman, Wahida, Dickenson, Anthony H.

“…Multiple pathological mechanisms at multiple sensory sites may underlie the pain that follows nerve injury. This provides a basis for recommending more than…”
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Preclinical and Early Clinical Investigations Related to Monoaminergic Pain Modulation by Bannister, Kirsty, Bee, Lucy A., Dickenson, Anthony H.

“…The balance between descending controls, both excitatory and inhibitory, can be altered in various pain states. There is good evidence for a prominent α…”
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Descending Serotonergic Facilitation and the Antinociceptive Effects of Pregabalin in a Rat Model of Osteoarthritic Pain by Rahman, Wahida, Bauer, Claudia S, Bannister, Kirsty, Vonsy, Jean-Laurent, Dolphin, Annette C, Dickenson, Anthony H

“…Background Descending facilitation, from the brainstem, promotes spinal neuronal hyperexcitability and behavioural hypersensitivity in many chronic pain…”
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Opicapone versus placebo in the treatment of Parkinson's disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial by Chaudhuri, K Ray, Odin, Per, Ferreira, Joaquim J, Antonini, Angelo, Rascol, Olivier, Kurtis, Mónica M, Storch, Alexander, Bannister, Kirsty, Soares-da-Silva, Patrício, Costa, Raquel, Magalhães, Diogo, Rocha, José Francisco

“…Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson's disease (PD). Opicapone (OPC) is a third-generation, once-daily…”
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Towards optimising experimental quantification of persistent pain in Parkinson’s disease using psychophysical testing by Bannister, Kirsty, Smith, Rory V., Wilkins, Patrick, Cummins, Tatum M.

“…People with Parkinson’s disease (PD) may live for multiple decades after diagnosis. Ensuring that effective healthcare provision is received across the range…”
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Editorial: Plasticity of Endogenous Pain Modulatory Circuits in Neuropathy by Patel, Ryan, Lumb, Bridget M, Bannister, Kirsty

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Pregabalin Suppresses Spinal Neuronal Hyperexcitability and Visceral Hypersensitivity in the Absence of Peripheral Pathophysiology by BANNISTER, Kirsty, SIKANDAR, Shafaq, BAUER, Claudia S, DOLPHIN, Annette C, PORRECA, Frank, DICKENSON, Anthony H

“…Opioid-induced hyperalgesia is recognized in the laboratory and the clinic, generating central hyperexcitability in the absence of peripheral pathology. We…”
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One size does not fit all: towards optimising the therapeutic potential of endogenous pain modulatory systems by Bannister, Kirsty, Hughes, Sam

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Pain Science in Practice (Part 7): How Is Descending Modulation of Pain Measured? by Hoegh, Morten, Bannister, Kirsty

“…Understanding the descending pain modulatory system allows for a neuroscientific explanation of naturally occurring pain relief. Evidence from basic science…”
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Effect of the spider toxin Tx3-3 on spinal processing of sensory information in naive and neuropathic rats: an in vivo electrophysiological study by Dalmolin, Gerusa D, Bannister, Kirsty, Gonçalves, Leonor, Sikandar, Shafaq, Patel, Ryan, Cordeiro, Marta do Nascimento, Gomez, Marcus Vinícius, Ferreira, Juliano, Dickenson, Anthony H

“…Drugs that counteract nociceptive transmission in the spinal dorsal horn preferentially after nerve injury are being pursued as possible neuropathic pain…”
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Pain Science in Practice (Part 6): How Does Descending Modulation of Pain Work? by Hoegh, Morten, Bannister, Kirsty

“…SYNOPSIS: To understand the neuroscience of pain relief, one must know about the descending pain modulatory system. Neuronal pathways that originate in the…”
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One size doesn’t fit all: towards optimising the therapeutic potential of endogenous pain modulatory systems by Bannister, Kirsty, Hughes, Sam

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