Search Results - "Bannard‐Smith, Jonathan"
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Insulin therapy in organ donation and transplantation
Published in Diabetes, obesity & metabolism (01-07-2019)“…Hyperglycaemia is common in hospitalized individuals, and is often caused by physiological stress associated with critical illness or major surgery. Insulin…”
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2
Albumin as a drug: Its biological effects beyond volume expansion
Published in Critical care and resuscitation (01-09-2020)“…- Albumin is the most abundant and perhaps most important protein in human blood. Research has identified many of albumin's possible roles in modulating…”
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3
The association of clinical frailty with outcomes of patients reviewed by rapid response teams: an international prospective observational cohort study
Published in Critical care (London, England) (22-09-2018)“…Frailty is a state of vulnerability to poor resolution of homeostasis after a stressor event and is strongly associated with adverse outcomes. Therefore, the…”
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ClinCirc identifies alterations of the circadian peripheral oscillator in critical care patients
Published in The Journal of clinical investigation (15-02-2023)“…BackgroundAssessing circadian rhythmicity from infrequently sampled data is challenging; however, these types of data are often encountered when measuring…”
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Speed of cooling after cardiac arrest in relation to the intervention effect: a sub-study from the TTM2-trial
Published in Critical care (London, England) (15-11-2022)“…Targeted temperature management (TTM) is recommended following cardiac arrest; however, time to target temperature varies in clinical practice. We hypothesised…”
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Haemodynamic and biochemical responses to fluid bolus therapy with human albumin solution, 4% versus 20%, in critically ill adults
Published in Critical care and resuscitation (01-06-2015)“…Background: Fluid bolus therapy (FBT) is common in critically ill patients. With the exception of use in patients with traumatic brain injury, FBT with human…”
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Preoperative assessment for patients with renal impairment
Published in Anaesthesia and intensive care medicine (01-07-2021)“…In health, the role of the kidneys includes regulation of crucial physiological variables such as blood pressure, acid–base, fluid and electrolyte balance,…”
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Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial
Published in Intensive care medicine (01-02-2022)“…Purpose Fluid overload is common in critical illness and is associated with mortality. This study investigated the feasibility of a randomised trial comparing…”
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The efficacy, safety and effectiveness of hyperoncotic albumin solutions in patients with sepsis: A systematic review and meta-analysis
Published in Journal of the Intensive Care Society (01-08-2024)“…Background: Intravenous fluid therapy is a ubiquitous intervention for the management of patients with sepsis, however excessive cumulative fluid balance has…”
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Quality metrics for the evaluation of Rapid Response Systems: Proceedings from the third international consensus conference on Rapid Response Systems
Published in Resuscitation (01-08-2019)“…Clinically significant deterioration of patients admitted to general wards is a recognized complication of hospital care. Rapid Response Systems (RRS) aim to…”
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The Barriers and Enablers to Single-Specialty Status in Critical Care
Published in Critical care medicine (01-06-2016)Get full text
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Clinical outcomes of patients seen by Rapid Response Teams: A template for benchmarking international teams
Published in Resuscitation (01-10-2016)“…Abstract Aim The study was developed to characterize short-term outcomes of deteriorating ward patients triggering a Rapid Response Team (RRT), and describe…”
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Small volume resuscitation with 20% albumin in intensive care: physiological effects: The SWIPE randomised clinical trial
Published in Intensive care medicine (01-11-2018)“…Purpose We set out to assess the resuscitation fluid requirements and physiological and clinical responses of intensive care unit (ICU) patients resuscitated…”
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Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cells (REALIST-COVID Trial): A Multicenter, Randomized, Controlled Clinical Trial
Published in American journal of respiratory and critical care medicine (01-08-2023)“…Mesenchymal stromal cells (MSCs) may modulate inflammation, promoting repair in coronavirus disease (COVID-19)-related acute respiratory distress syndrome…”
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Correction: Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation Correction: After Resuscitation-2 (RADAR-2) randomised clinical trial
Published in Intensive care medicine (01-11-2023)Get full text
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16
Critical Illness on General Floors: Reliability Plus Redundancy Equals Resilience?
Published in Critical care medicine (01-07-2015)Get full text
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Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation
Published in The lancet respiratory medicine (01-02-2020)“…Ventilator-associated pneumonia is the most common intensive care unit (ICU)-acquired infection, yet accurate diagnosis remains difficult, leading to overuse…”
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Microbial Volatiles as Diagnostic Biomarkers of Bacterial Lung Infection in Mechanically Ventilated Patients
Published in Clinical infectious diseases (21-03-2023)“…Abstract Background Early and accurate recognition of respiratory pathogens is crucial to prevent increased risk of mortality in critically ill patients…”
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Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia
Published in Critical care (London, England) (06-07-2022)“…Background Ventilator-associated pneumonia (VAP) is associated with high morbidity and health care costs, yet diagnosis remains a challenge. Analysis of airway…”
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Detection and quantification of exhaled volatile organic compounds in mechanically ventilated patients - comparison of two sampling methods
Published in Analyst (London) (04-01-2021)“…Exhaled breath analysis is a promising new diagnostic tool, but currently no standardised method for sampling is available in mechanically ventilated patients…”
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