Search Results - "Banks, Tereece"

Spirolactam-Based Acetyl-CoA Carboxylase Inhibitors: Toward Improved Metabolic Stability of a Chromanone Lead Structure by Griffith, David A, Dow, Robert L, Huard, Kim, Edmonds, David J, Bagley, Scott W, Polivkova, Jana, Zeng, Dongxiang, Garcia-Irizarry, Carmen N, Southers, James A, Esler, William, Amor, Paul, Loomis, Kathrine, McPherson, Kirk, Bahnck, Kevin B, Préville, Cathy, Banks, Tereece, Moore, Dianna E, Mathiowetz, Alan M, Menhaji-Klotz, Elnaz, Smith, Aaron C, Doran, Shawn D, Beebe, David A, Dunn, Matthew F

“…Acetyl-CoA carboxylase (ACC) catalyzes the rate-determining step in de novo lipogenesis and plays a crucial role in the regulation of fatty acid oxidation…”
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Identification of (R)‑6-(1-(4-Cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro‑1H‑pyrazol-3-yl)-2-methoxynicotinic Acid, a Highly Potent and Selective Nonsteroidal Mineralocorticoid Receptor Antagonist by Casimiro-Garcia, Agustin, Piotrowski, David W, Ambler, Catherine, Arhancet, Graciela B, Banker, Mary Ellen, Banks, Tereece, Boustany-Kari, Carine M, Cai, Cuiman, Chen, Xiangyang, Eudy, Rena, Hepworth, David, Hulford, Catherine A, Jennings, Sandra M, Loria, Paula M, Meyers, Marvin J, Petersen, Donna N, Raheja, Neil K, Sammons, Matthew, She, Li, Song, Kun, Vrieze, Derek, Wei, Liuqing

“…A novel series of nonsteroidal mineralocorticoid receptor (MR) antagonists identified as part of our strategy to follow up on the clinical candidate…”
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Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase by Kung, Daniel W., Griffith, David A., Esler, William P., Vajdos, Felix F., Mathiowetz, Alan M., Doran, Shawn D., Amor, Paul A., Bagley, Scott W., Banks, Tereece, Cabral, Shawn, Ford, Kristen, Garcia-Irizarry, Carmen N., Landis, Margaret S., Loomis, Kathrine, McPherson, Kirk, Niosi, Mark, Rockwell, Kristin L., Rose, Colin, Smith, Aaron C., Southers, James A., Tapley, Susan, Tu, Meihua, Valentine, James J.

“…[Display omitted] A novel series of spirocyclic-diamine based, isoform non-selective inhibitors of acetyl-CoA carboxylase (ACC) is described. These…”
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Identification of ( R )-6-(1-(4-Cyano-3-methylphenyl)-5-cyclopentyl-4,5-dihydro-1 H -pyrazol-3-yl)-2-methoxynicotinic Acid, a Highly Potent and Selective Nonsteroidal Mineralocorticoid Receptor Antagonist by Casimiro-Garcia, Agustin, Piotrowski, David W., Ambler, Catherine, Arhancet, Graciela B., Banker, Mary Ellen, Banks, Tereece, Boustany-Kari, Carine M., Cai, Cuiman, Chen, Xiangyang, Eudy, Rena, Hepworth, David, Hulford, Catherine A., Jennings, Sandra M., Loria, Paula M., Meyers, Marvin J., Petersen, Donna N., Raheja, Neil K., Sammons, Matthew, She, Li, Song, Kun, Vrieze, Derek, Wei, Liuqing

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Relationship between Salt-Bridge Identity and 14-Helix Stability of β 3 -Peptides in Aqueous Buffer by Guarracino, Danielle A., Chiang, HyoJin R., Banks, Tereece N., Lear, James D., Hodsdon, Michael E., Schepartz, Alanna

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Relationship between salt-bridge identity and 14-helix stability of beta3-peptides in aqueous buffer by Guarracino, Danielle A, Chiang, Hyojin R, Banks, Tereece N, Lear, James D, Hodsdon, Michael E, Schepartz, Alanna

“…We report a systematic analysis of the relationship between salt bridge composition and 14-helix structure within a family of model beta-peptides in aqueous…”
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Relationship between Salt-Bridge Identity and 14-Helix Stability of β3-Peptides in Aqueous Buffer by Guarracino, Danielle A, Chiang, HyoJin R, Banks, Tereece N, Lear, James D, Hodsdon, Michael E, Schepartz, Alanna

“…We report a systematic analysis of the relationship between salt bridge composition and 14-helix structure within a family of model β-peptides in aqueous…”
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