Search Results - "Bank, RA"
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Microsphere size influences the foreign body reaction
Published in European cells & materials (28-10-2014)“…Biodegradable poly-(DL-lactide-co-glycolide) (PLGA) microspheres (MSP) are attractive candidate vehicles for site-specific or systemic sustained release of…”
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Lysyl Oxidase: New Looks on LOX
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2002)Get full text
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Endo180 and MT1-MMP are involved in the phagocytosis of collagen scaffolds by macrophages and is regulated by interferon-gamma
Published in European cells & materials (07-10-2010)“…Subcutaneously implanted disks of hexamethylenediisocyanate or glutaraldehyde cross-linked sheep collagen (referred to as HDSC and GDSC, respectively) in mice…”
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A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue
Published in Experimental cell research (15-04-2014)“…Promising renal replacement therapies include the development of a bioartificial kidney using functional human kidney cell models. In this study, human…”
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Effect of Collagen Turnover on the Accumulation of Advanced Glycation End Products
Published in The Journal of biological chemistry (15-12-2000)“…Collagen molecules in articular cartilage have an exceptionally long lifetime, which makes them susceptible to the accumulation of advanced glycation end…”
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Trabecular microfracture and the influence of pyridinium and non-enzymatic glycation-mediated collagen cross-links
Published in Bone (New York, N.Y.) (01-12-2005)“…The propensity of individual trabeculae to fracture (microfracture) may be important clinically since it could be indicative of bone fragility. Whether or not…”
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Identification of PLOD2 as Telopeptide Lysyl Hydroxylase, an Important Enzyme in Fibrosis
Published in The Journal of biological chemistry (17-10-2003)“…The hallmark of fibrotic processes is an excessive accumulation of collagen. The deposited collagen shows an increase in pyridinoline cross-links, which are…”
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Impaired Collagen Biosynthesis and Cross‐linking in Aorta of Patients With Bicuspid Aortic Valve
Published in Journal of the American Heart Association (2013)“…Background Patients with bicuspid aortic valve (BAV) have an increased risk of developing ascending aortic aneurysm. In the present study, collagen homeostasis…”
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The role of collagen in determining bone mechanical properties
Published in Journal of orthopaedic research (01-11-2001)“…The hypothesis of this study was that collagen denaturation would lead to a significant decrease in the toughness of bone, but has little effect on the…”
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Matrix metalloproteinase activities and their relationship with collagen remodelling in tendon pathology
Published in Matrix biology (01-03-2002)“…Our aim was to correlate the activity of matrix metalloproteinases (MMPs) with denaturation and the turnover of collagen in normal and pathological human…”
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AGEing and osteoarthritis: a different perspective
Published in Current opinion in rheumatology (01-09-2003)“…PURPOSE OF REVIEWAcross the world, osteoarthritis is the most commonly occurring musculoskeletal disease of the elderly, affecting more than 25% of the…”
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Age-related accumulation of Maillard reaction products in human articular cartilage collagen
Published in Biochemical journal (01-09-2000)“…Non-enzymic modification of tissue proteins by reducing sugars, the so-called Maillard reaction, is a prominent feature of aging. In articular cartilage,…”
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Phenotypic and molecular characterization of Bruck syndrome (osteogenesis imperfecta with contractures of the large joints) caused by a recessive mutation in PLOD2
Published in American journal of medical genetics. Part A (01-12-2004)“…Bruck syndrome (BS) is a recessively‐inherited phenotypic disorder featuring the unusual combination of skeletal changes resembling osteogenesis imperfecta…”
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15
The type of collagen cross-link determines the reversibility of experimental skin fibrosis
Published in Biochimica et biophysica acta (15-04-2005)“…Fibrotic processes in humans are characterised by an excessive accumulation of collagen containing increased levels of hydroxyallysine-derived cross-links. The…”
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Decreased Collagen Organization and Content Are Associated With Reduced Strength of Demineralized and Intact Bone in the SAMP6 Mouse
Published in Journal of bone and mineral research (01-01-2006)“…To examine the link between bone material properties and skeletal fragility, we analyzed the mechanical, histological, biochemical, and spectroscopic…”
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Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon
Published in Matrix biology (01-07-2004)“…Fibrosis is characterized by an excessive accumulation of collagen which contains increased levels of pyridinoline cross-links. The occurrence of pyridinolines…”
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Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels
Published in Biochimica et biophysica acta (30-06-2005)“…The hallmark of fibrosis is the excessive accumulation of collagen. The deposited collagen contains increased pyridinoline cross-link levels due to an…”
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Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage
Published in Biochemical journal (15-02-1998)“…A biomechanical failure of the collagen network is postulated in many hypotheses of the development of osteoarthritis with advancing age. Here we investigate…”
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Mechanical Properties of the Collagen Network in Human Articular Cartilage as Measured by Osmotic Stress Technique
Published in Archives of biochemistry and biophysics (15-03-1998)“…We have used an isotropic osmotic stress technique to assess the swelling pressures of human articular cartilage over a wide range of hydrations in order to…”
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