Search Results - "Banini, Bubu A."

Molecular Mechanisms of Lipotoxicity and Glucotoxicity in Nonalcoholic Fatty Liver Disease by Mota, Manoela, Banini, Bubu A, Cazanave, Sophie C, Sanyal, Arun J

“…Abstract The exposure of hepatocytes to high concentrations of lipids and carbohydrates and the ensuing hepatocellular injury are termed lipotoxicity and…”
Get full text

Nonalcoholic liver disease: Epidemiology, risk factors, natural history, and management strategies by Agyapong, George, Dashti, Farzaneh, Banini, Bubu A.

“…Nonalcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease worldwide and a leading indication for liver transplantation in the…”
Get full text

A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer by Asgharpour, Amon, Cazanave, Sophie C, Pacana, Tommy, Seneshaw, Mulugeta, Vincent, Robert, Banini, Bubu A, Kumar, Divya Prasanna, Daita, Kalyani, Min, Hae-Ki, Mirshahi, Faridoddin, Bedossa, Pierre, Sun, Xiaochen, Hoshida, Yujin, Koduru, Srinivas V, Contaifer, Daniel, Warncke, Urszula Osinska, Wijesinghe, Dayanjan S, Sanyal, Arun J

“…Graphical abstract…”
Get full text

Current and future pharmacologic treatment of nonalcoholic steatohepatitis by Banini, Bubu A, Sanyal, Arun J

“…PURPOSE OF REVIEWNonalcoholic steatohepatitis (NASH), the aggressive form of nonalcoholic fatty liver disease (NAFLD), can progress to cirrhosis and…”
Get full text

Derivation and Validation of a Model to Predict Clinically Significant Portal Hypertension Using Transient Elastography and FIB-4 by Banini, Bubu A., Patel, Samarth, Yu, Jonathan W., Kang, Le, Bailey, Christopher, Strife, Brian J., Siddiqui, Mohammad S., Patel, Vaishali, Matherly, Scott C., Lee, Hannah, Lewis, Shawn, Cherian, Reena, Stravitz, Richard T., Luketic, Velimir, Sanyal, Arun J., Sterling, Richard K.

“…Liver biopsy and hepatic venous pressure gradient (HVPG), the gold standard for assessing advanced fibrosis (AF) and clinically significant portal hypertension…”
Get full text

Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling by Nakamura, Ikuo, Zakharia, Kais, Banini, Bubu A, Mikhail, Dalia S, Kim, Tae Hyo, Yang, Ju Dong, Moser, Catherine D, Shaleh, Hassan M, Thornburgh, Sarah R, Walters, Ian, Roberts, Lewis R

“…Brivanib is a selective inhibitor of vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) tyrosine kinases, which…”
Get full text

Correction: Brivanib Attenuates Hepatic Fibrosis In Vivo and Stellate Cell Activation In Vitro by Inhibition of FGF, VEGF and PDGF Signaling by Nakamura, Ikuo, Zakharia, Kais, Banini, Bubu A, Mikhail, Dalia S, Kim, Tae Hyo, Yang, Ju Dong, Moser, Catherine D, Shaleh, Hassan M, Thornburgh, Sarah R, Walters, Ian, Roberts, Lewis R

Get full text

The impact of MELD exception points for hydrothorax on posttransplant mortality: a propensity score-matched analysis by Fathma, Sawsan, Boateng, Sarpong, Amatya, Ayesha, Ameyaw, Prince, Banini, Bubu A

“…Hepatic hydrothorax is a challenging complication of end-stage liver disease, and.patients with this complication can receive model for end-stage liver disease…”
Get full text

Hepatic Hydrothorax: An Independent Predictor of Mortality in Cirrhosis? Is the MELD-Na Score Worth Its Salt? by Asotibe, Jennifer C., Banini, Bubu A.

Get full text

Multidisciplinary Management of Hepatic Hydrothorax in 2020: An Evidence‐Based Review and Guidance by Banini, Bubu A., Alwatari, Yahya, Stovall, Madeline, Ogden, Nathan, Gershman, Evgeni, Shah, Rachit D., Strife, Brian J., Shojaee, Samira, Sterling, Richard K.

Get full text

Digoxin as an emerging therapy in noncardiac diseases by Dashti, Farzaneh, Jamshed, Fatima, Ouyang, Xinshou, Mehal, Wajahat Z., Banini, Bubu A.

“…The cardiac glycoside (CG) digoxin is a generic drug approved for the treatment of heart failure and supraventricular arrhythmias. Over the past few decades,…”
Get full text

New uses for an old remedy: Digoxin as a potential treatment for steatohepatitis and other disorders by Jamshed, Fatima, Dashti, Farzaneh, Ouyang, Xinshou, Mehal, Wajahat Z, Banini, Bubu A

“…Repurposing of the widely available and relatively cheap generic cardiac gly-coside digoxin for non-cardiac indications could have a wide-ranging impact on the…”
Get full text

Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis by Banini, Bubu A., Kumar, Divya P., Cazanave, Sophie, Seneshaw, Mulugeta, Mirshahi, Faridoddin, Santhekadur, Prasanna K., Wang, Liangsu, Guan, Hong Ping, Oseini, Abdul M., Alonso, Cristina, Bedossa, Pierre, Koduru, Srinivas V., Min, Hae‐Ki, Sanyal, Arun J.

“…Background and Aims The mechanisms by which the I148M mutant variant of the patatin‐like phospholipase domain‐containing 3 (PNPLA3I148M) drives development of…”
Get full text

Editorial: Recent advances in the understanding of hepatocellular carcinogenesis by Banini, Bubu A., Mehta, Rohini, Santhekadur, Prasanna K.

Get full text

Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis by Chen, George, Banini, Bubu A, Do, Albert, Gunderson, Craig, Zaman, Saif, Lim, Joseph K

“…The independent effect of exercise on liver histology in non-alcoholic fatty liver disease (NAFLD) remains unclear. As such, we conducted a systematic review…”
Get full text

Role of candidate gene variants in modulating the risk and severity of alcoholic hepatitis by Beaudoin, James J., Liang, Tiebing, Tang, Qing, Banini, Bubu A., Shah, Vijay H., Sanyal, Arun J., Chalasani, Naga P., Gawrieh, Samer

“…Background Alcoholic hepatitis (AH) is a severe and life‐threatening alcohol‐associated liver disease. Only a minority of heavy drinkers acquires AH and…”
Get full text

Screening, Diagnosis, and Staging of Non-Alcoholic Fatty Liver Disease (NAFLD): Application of Society Guidelines to Clinical Practice by Ilagan-Ying, Ysabel C., Banini, Bubu A., Do, Albert, Lam, Robert, Lim, Joseph K.

“…Purpose of Review Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly nonalcoholic fatty liver disease (NAFLD), is the most common…”
Get full text

Treatment of NASH: What Helps Beyond Weight Loss? by Banini, Bubu A, Sanyal, Arun J

Get full text

Enlarging Ectopic Thyroid in the Porta Hepatis: 2434 by Banini, Bubu A., Matherly, Scott C., Lee, Hannah M.

“…Introduction: Ectopic thyroid tissue usually occurs in the neck and chest. There have been only three case reports of ectopic thyroid in the porta hepatis;…”
Get full text

NAFLD-related HCC by Banini, Bubu A, Sanyal, Arun J

“…Nonalcoholic fatty liver disease (NAFLD) is one of the major drivers for the rising trend in hepatocellular carcinoma (HCC). Over the past three decades, the…”
Get full text