Search Results - "Banham, Alison H."

Therapeutic Antibodies against Intracellular Tumor Antigens by Trenevska, Iva, Li, Demin, Banham, Alison H

“…Monoclonal antibodies are among the most clinically effective drugs used to treat cancer. However, their target repertoire is limited as there are relatively…”
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A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis by Masiero, Massimo, Simões, Filipa Costa, Han, Hee Dong, Snell, Cameron, Peterkin, Tessa, Bridges, Esther, Mangala, Lingegowda S., Wu, Sherry Yen-Yao, Pradeep, Sunila, Li, Demin, Han, Cheng, Dalton, Heather, Lopez-Berestein, Gabriel, Tuynman, Jurriaan B., Mortensen, Neil, Li, Ji-Liang, Patient, Roger, Sood, Anil K., Banham, Alison H., Harris, Adrian L., Buffa, Francesca M.

“…Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new targets involved in tumor angiogenesis. Here, we report an…”
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Notch signaling: its roles and therapeutic potential in hematological malignancies by Gu, Yisu, Masiero, Massimo, Banham, Alison H

“…Notch is a highly conserved signaling system that allows neighboring cells to communicate, thereby controlling their differentiation, proliferation and…”
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The significance of FOXP1 in diffuse large B-cell lymphoma by Gascoyne, Duncan M., Banham, Alison H.

“…Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of mature B-cell lymphoma. While the majority of patients are cured with immunochemotherapy…”
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The notch ligand JAGGED1 as a target for anti-tumor therapy by Li, Demin, Masiero, Massimo, Banham, Alison H, Harris, Adrian L

“…The Notch pathway is increasingly attracting attention as a source of therapeutic targets for cancer. Ligand-induced Notch signaling has been implicated in…”
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Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse by BATES, Gaynor J, FOX, Stephen B, CHENG HAN, LEEK, Russell D, GARCIA, José F, HARRIS, Adrian L, BANHAM, Alison H

“…To assess the clinical significance of tumor-infiltrating FOXP3-positive regulatory T cells (TR) in breast cancer patients with long-term follow-up…”
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A New Immunostain Algorithm Classifies Diffuse Large B-Cell Lymphoma into Molecular Subtypes with High Accuracy by CHOI, William W. L, WEISENBURGER, Dennis D, VOSE, Julie M, HANS, Christine P, KAI FU, SMITH, Lynette M, MIN LI, ZHONGFENG LIU, GASCOYNE, Randy D, ROSENWALD, Andreas, OTT, German, RIMSZA, Lisa M, GREINER, Timothy C, CAMPO, Elias, JAFFE, Elaine S, JAYE, David L, STAUDT, Louis M, CHAN, Wing C, PIRIS, Miguel A, BANHAM, Alison H, DELABIE, Jan, BRAZIEL, Rita M, HUIMIN GENG, IQBAL, Javeed, LENZ, Georg

“…Purpose: Hans and coworkers previously developed an immunohistochemical algorithm with ∼80% concordance with the gene expression profiling (GEP)…”
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ADGRL4/ELTD1 is a highly conserved angiogenesis-associated orphan adhesion GPCR that emerged with the first vertebrates and comprises 3 evolutionary variants by Favara, David M, Banham, Alison H, Harris, Adrian L

“…Our laboratory identified ADGRL4/ELTD1, an orphan GPCR belonging to the adhesion GPCR (aGPCR) family, as a novel regulator of angiogenesis and a potential…”
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Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling by Favara, David M., Liebscher, Ines, Jazayeri, Ali, Nambiar, Madhulika, Sheldon, Helen, Banham, Alison H., Harris, Adrian L.

“…ADGRL4/ELTD1 is an orphan adhesion GPCR (aGPCR) expressed in endothelial cells that regulates tumour angiogenesis. The majority of aGPCRs are orphan receptors…”
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Cancer/Testis Antigen PASD1 Silences the Circadian Clock by Michael, Alicia K., Harvey, Stacy L., Sammons, Patrick J., Anderson, Amanda P., Kopalle, Hema M., Banham, Alison H., Partch, Carrie L.

“…The circadian clock orchestrates global changes in transcriptional regulation on a daily basis via the bHLH-PAS transcription factor CLOCK:BMAL1. Pathways…”
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ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype by Sheldon, Helen, Alexander, John, Bridges, Esther, Moreira, Lucia, Reilly, Svetlana, Ang, Koon Hwee, Wang, Dian, Lin, Salwa, Haider, Syed, Banham, Alison H, Harris, Adrian L

“…ELTD1 is expressed in endothelial and vascular smooth muscle cells and has a role in angiogenesis. It has been classified as an adhesion GPCR, but as yet, no…”
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Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A0201 by Trenevska, Iva, Anderson, Amanda P, Bentley, Carol, Hassanali, Tasneem, Wiblin, Sarah, Maguire, Shaun, Pezzella, Francesco, Banham, Alison H, Li, Demin

“…T-cell receptor mimic (TCRm) antibodies have expanded the repertoire of antigens targetable by monoclonal antibodies, to include peptides derived from…”
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The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest by Gascoyne, Duncan M, Spearman, Hayley, Lyne, Linden, Puliyadi, Rathi, Perez-Alcantara, Marta, Coulton, Les, Fisher, Simon E, Croucher, Peter I, Banham, Alison H

“…Mutations of the forkhead transcription factor FOXP2 gene have been implicated in inherited speech-and-language disorders, and specific Foxp2 expression…”
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High-mobility group box (TOX) antibody a useful tool for the identification of B and T cell subpopulations by Maestre, Lorena, García-García, Juan Fernando, Jiménez, Scherezade, Reyes-García, Ana Isabel, García-González, Álvaro, Montes-Moreno, Santiago, Arribas, Alberto J, González-García, Patricia, Caleiras, Eduardo, Banham, Alison H, Piris, Miguel Ángel, Roncador, Giovanna

“…Thymocyte selection-associated high-mobility group box (TOX) is a DNA-binding factor that is able to regulate transcription by modifying local chromatin…”
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A review of ELTD1, a pro-angiogenic adhesion GPCR by Favara, David M, Banham, Alison H, Harris, Adrian L

“…Epidermal growth factor, latrophilin and seven-transmembrane domain-containing 1 (ELTD1), an orphan G-protein-coupled receptor (GPCR) belonging to the adhesion…”
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FOXP3+ regulatory T cells: Current controversies and future perspectives by Banham, Alison H., Powrie, Fiona M., Suri‐Payer, Elisabeth

“…Regulatory T cells (Treg) provide protection from autoimmune disease, graft‐versus‐host disease, transplant rejection and overwhelming tissue destruction…”
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Immunomodulation of FOXP3+ Regulatory T Cells by the Aromatase Inhibitor Letrozole in Breast Cancer Patients by GENERALI, Daniele, BATES, Gaynor, DOGLIOTTI, Luigi, BANHAM, Alison H, HARRIS, Adrian L, BOTTINI, Alberto, FOX, Stephen B, BERRUTI, Alfredo, BRIZZI, Maria P, CAMPO, Leticia, BONARDI, Simone, BERSIGA, Alessandra, ALLEVI, Giovanni, MILANI, Manuela, AGUGGINI, Sergio

“…Purpose: We have shown previously that tumor infiltration by FOXP3 + regulatory T cells (Treg) is associated with increased relapse and shorter survival of…”
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Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia by Ferland, Russell J., Batiz, Luis Federico, Neal, Jason, Lian, Gewei, Bundock, Elizabeth, Lu, Jie, Hsiao, Yi-Chun, Diamond, Rachel, Mei, Davide, Banham, Alison H., Brown, Philip J., Vanderburg, Charles R., Joseph, Jeffrey, Hecht, Jonathan L., Folkerth, Rebecca, Guerrini, Renzo, Walsh, Christopher A., Rodriguez, Esteban M., Sheen, Volney L.

“…Periventricular heterotopia (PH) is a disorder characterized by neuronal nodules, ectopically positioned along the lateral ventricles of the cerebral cortex…”
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Immunophenotypic Analysis of AIDS-Related Diffuse Large B-Cell Lymphoma and Clinical Implications in Patients From AIDS Malignancies Consortium Clinical Trials 010 and 034 by CHADBURN, Amy, CHIU, April, CESARMAN, Ethel, LEE, Jeannette Y, XIA CHEN, HYJEK, Elizabeth, BANHAM, Alison H, NOY, Ariela, KAPLAN, Lawrence D, SPARANO, Joseph A, BHATIA, Kishor

“…Diffuse large B-cell lymphoma (DLBCL) represents a clinically heterogeneous disease. Models based on immunohistochemistry predict clinical outcome. These…”
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Outcome in Hodgkin's Lymphoma Can Be Predicted from the Presence of Accompanying Cytotoxic and Regulatory T Cells by ALVARO, Tomas, LEJEUNE, Marylène, SALVADO, Ma Teresa, BOSCH, Ramon, GARCIA, Juan F, JAEN, Joaquin, BANHAM, Alison H, RONCADOR, Giovanna, MONTALBAN, Carlos, PIRIS, Miguel A

“…Purpose: Recent studies of Hodgkin's lymphoma (HL) have suggested that the presence of regulatory T cells in the reactive background may explain the inhibition…”
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