Search Results - "Banerjee, Sangeeta R"
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A prostate-specific membrane antigen (PSMA)-targeted prodrug with a favorable in vivo toxicity profile
Published in Scientific reports (29-03-2021)“…Prostate-specific membrane antigen (PSMA) is a promising target for the treatment of advanced prostate cancer (PC) and various solid tumors. Although…”
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PSMA-Targeted Theranostic Nanoplex for Prostate Cancer Therapy
Published in ACS nano (25-09-2012)“…Theranostic imaging, where diagnosis is combined with therapy, is particularly suitable for a disease that is as complex as cancer, especially now that genomic…”
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Synthesis and Biological Evaluation of Low Molecular Weight Fluorescent Imaging Agents for the Prostate-Specific Membrane Antigen
Published in Bioconjugate chemistry (19-12-2012)“…Targeted near-infrared (NIR) optical imaging can be used in vivo to detect specific tissues, including malignant cells. A series of NIR fluorescent ligands…”
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Synthesis and Evaluation of Technetium-99m- and Rhenium-Labeled Inhibitors of the Prostate-Specific Membrane Antigen (PSMA)
Published in Journal of medicinal chemistry (14-08-2008)“…The prostate-specific membrane antigen (PSMA) is increasingly recognized as a viable target for imaging and therapy of cancer. We prepared seven…”
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Characterization of a targeted nanoparticle functionalized with a urea-based inhibitor of prostate-specific membrane antigen (PSMA)
Published in Cancer biology & therapy (01-06-2008)“…Polymeric nanoparticles represent a form of targeted therapy due to their ability to passively accumulate within the tumor interstitium via the enhanced…”
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111 In- and IRDye800CW-Labeled PLA-PEG Nanoparticle for Imaging Prostate-Specific Membrane Antigen-Expressing Tissues
Published in Biomacromolecules (09-01-2017)“…Targeted delivery of drug-encapsulated nanoparticles is a promising new approach to safe and effective therapeutics for cancer. Here we investigate the…”
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PSMA-specific theranostic nanoplex for combination of TRAIL gene and 5-FC prodrug therapy of prostate cancer
Published in Biomaterials (01-02-2016)“…Abstract Metastatic prostate cancer causes significant morbidity and mortality and there is a critical unmet need for effective treatments. We have developed a…”
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Heterobivalent Agents Targeting PSMA and Integrin‑αvβ3
Published in Bioconjugate chemistry (19-02-2014)“…Differential expression of surface proteins on normal vs malignant cells provides the rationale for the development of receptor-, antigen-, and…”
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MRI Assessment of Prostate-Specific Membrane Antigen (PSMA) Targeting by a PSMA-Targeted Magnetic Nanoparticle: Potential for Image-Guided Therapy
Published in Molecular pharmaceutics (06-05-2019)“…Magnetic nanoparticle (MNP)-induced hyperthermia is currently being evaluated for localized prostate cancer. We evaluated the feasibility of tumor-selective…”
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Auger radiopharmaceutical therapy targeting prostate-specific membrane antigen in a micrometastatic model of prostate cancer
Published in Theranostics (01-01-2020)“…Auger radiopharmaceutical therapy is a promising strategy for micrometastatic disease given high linear energy transfer and short range in tissues, potentially…”
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Evaluation of a PSMA-targeted BNF nanoparticle construct
Published in Nanoscale (14-03-2015)“…Early detection enables improved prognosis for prostate cancer (PCa). A promising target for imaging and therapy of PCa is the prostate-specific membrane…”
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Interactions between Human Glutamate Carboxypeptidase II and Urea-Based Inhibitors: Structural Characterization
Published in Journal of medicinal chemistry (25-12-2008)“…Urea-based, low molecular weight ligands of glutamate carboxypeptidase II (GCPII) have demonstrated efficacy in various models of neurological disorders and…”
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13
111In- and IRDye800CW-Labeled PLA–PEG Nanoparticle for Imaging Prostate-Specific Membrane Antigen-Expressing Tissues
Published in Biomacromolecules (09-01-2017)“…Targeted delivery of drug-encapsulated nanoparticles is a promising new approach to safe and effective therapeutics for cancer. Here we investigate the…”
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14
Probing In Vivo Trafficking of Polymer/DNA Micellar Nanoparticles Using SPECT/CT Imaging
Published in Molecular therapy (01-09-2011)“…Successful translation of nonviral gene delivery to therapeutic applications requires detailed understanding of in vivo trafficking of the vehicles. This…”
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Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors
Published in Nanotheranostics (Sydney, NSW) (2021)“…Enhanced vascular permeability in tumors plays an essential role in nanoparticle delivery. Prostate-specific membrane antigen (PSMA) is overexpressed on the…”
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Comprehensive Radiolabeling, Stability, and Tissue Distribution Studies of Technetium-99m Single Amino Acid Chelates (SAAC)
Published in Bioconjugate chemistry (19-08-2009)“…Technetium tricarbonyl chemistry has been a subject of interest in radiopharmaceutical development over the past decade. Despite the extensive work done on…”
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17
Albumin-based nanoformulation for prostate-specific membrane antigen (PSMA)
Published in Nuclear medicine and biology (01-08-2014)Get full text
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18
Optimization of peptide-based inhibitors of prostate-specific antigen (PSA) as targeted imaging agents for prostate cancer
Published in Bioorganic & medicinal chemistry (15-07-2009)“…Prostate-specific antigen (PSA) is a serine protease biomarker that may play a role in prostate cancer development and progression. The inhibition of PSA’s…”
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N,N-Bis(2-mercaptoethyl)methylamine: A New Coligand for Tc-99m Labeling of Hydrazinonicotinamide Peptides
Published in Bioconjugate chemistry (01-07-2005)“…Hydrazinonicotinamide (HYNIC) forms stable coordination complexes with Tc-99m when reacted with Tc(V)oxo species such as Tc-mannitol or other Tc-polyhydric…”
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Abstract 5070: Prostate-specific membrane antigen (PSMA) targeted multiplexed siRNA-mediated gene silencing of CD46 and PD-L1 in prostate cancer
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Small interfering RNA are suitable for gene silencing through a sequence-specific RNA interference process. The redundancy and complexity of molecular…”
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