Search Results - "Banerjee, Kalpita"
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Lipofuscin causes atypical necroptosis through lysosomal membrane permeabilization
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2021)“…Lipofuscin granules enclose mixtures of cross-linked proteins and lipids in proportions that depend on the tissue analyzed. Retinal lipofuscin is unique in…”
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Mitochondrial dysfunction mediated by quinone oxidation products of dopamine: Implications in dopamine cytotoxicity and pathogenesis of Parkinson's disease
Published in Biochimica et biophysica acta (01-06-2011)“…The study has demonstrated that dopamine induces membrane depolarization and a loss of phosphorylation capacity in dose-dependent manner in isolated rat brain…”
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Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
Published in Cell communication and signaling (15-12-2016)“…STAT3 is increasingly becoming known for its non-transcriptional regulation of mitochondrial bioenergetic function upon activation of its S727 residue…”
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Correction to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
Published in Cell communication and signaling (20-04-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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Dopamine Cytotoxicity Involves Both Oxidative and Nonoxidative Pathways in SH-SY5Y Cells: Potential Role of Alpha-Synuclein Overexpression and Proteasomal Inhibition in the Etiopathogenesis of Parkinson’s Disease
Published in Parkinson's disease (01-01-2014)“…Background. The cytotoxic effects of dopamine (DA) on several catecholaminergic cell lines involve DA oxidation products like reactive oxygen species (ROS) and…”
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Erratum to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
Published in Cell communication and signaling (27-03-2017)“…Unfortunately, after publication of this article [1], it was noticed that the Acknowledgements and Funding sections were incomplete. The Acknowledgements…”
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Reduced FAK-STAT3 signaling contributes to ER stress-induced mitochondrial dysfunction and death in endothelial cells
Published in Cellular signalling (01-08-2017)“…Excessive endoplasmic reticulum (ER) stress leads to cell loss in many diseases, e.g., contributing to endothelial cell loss after spinal cord injury. Here, we…”
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α-Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson’s disease
Published in FEBS letters (16-04-2010)“…This study demonstrates that in vitro incubation of isolated rat brain mitochondria with recombinant human α-synuclein leads to dose-dependent loss of…”
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Abnormal Glucose Metabolism in Alzheimer’s Disease: Relation to Autophagy/Mitophagy and Therapeutic Approaches
Published in Neurochemical research (01-12-2015)“…Diminished glucose metabolism accompanies many neurodegenerative diseases including Alzheimer’s disease. An understanding of the relation of these metabolic…”
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Mitochondrial Dysfunction during Brain Aging: Role of Oxidative Stress and Modulation by Antioxidant Supplementation
Published in Aging and disease (01-06-2011)“…Mitochondrial dysfunction and oxidative stress are two interdependent and reinforcing damage mechanisms that play a central role in brain aging. Oxidative…”
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Continuous Flow Synthesis of A2E Guided by Design of Experiments and High-Throughput Studies
Published in ACS bio & med chem au (15-06-2022)“…N-Retinylidene-N-retinylethanolamine (A2E) is the most studied lipid bisretinoid. It forms lipofuscin deposits in the retinal pigment epithelium (RPE), causing…”
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Mild mitochondrial metabolic deficits by α-ketoglutarate dehydrogenase inhibition cause prominent changes in intracellular autophagic signaling: Potential role in the pathobiology of Alzheimer's disease
Published in Neurochemistry international (01-06-2016)“…Brain activities of the mitochondrial enzyme α-ketoglutarate dehydrogenase complex (KGDHC) are reduced in Alzheimer's disease and other age-related…”
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Aging promotes amyloid-β peptide induced mitochondrial dysfunctions in rat brain: a molecular link between aging and Alzheimer's disease
Published in Journal of Alzheimer's disease (01-01-2011)“…The entangled relationship of brain aging, mitochondrial dysfunction, and amyloid-β peptide (Aβ₄₂) toxicity occupies the center stage in the pathogenesis of…”
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Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's disease
Published in Free radical research (01-01-2008)“…Dopamine oxidation products such as H2O2 and reactive quinones have been held responsible for various toxic actions of dopamine, which have implications in the…”
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a-Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson's disease
Published in FEBS letters (16-04-2010)“…This study demonstrates that in vitro incubation of isolated rat brain mitochondria with recombinant human a-synuclein leads to dose-dependent loss of…”
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Dopamine but not 3,4-dihydroxy phenylacetic acid (DOPAC) inhibits brain respiratory chain activity by autoxidation and mitochondria catalyzed oxidation to quinone products: Implications in Parkinson's disease
Published in Brain research (30-03-2007)“…Abstract This study reveals that, in contrast to dopamine (DA), 3,4 dihydroxyphenylacetic acid (DOPAC) during in vitro incubation up to 2 h causes only…”
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