Search Results - "Banerjee, Dipak K"
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N-glycans in cell survival and death: Cross-talk between glycosyltransferases
Published in Biochimica et biophysica acta (01-09-2012)“…Asparagine-linked (N-linked) protein glycosylation is one of the most important protein modifications. N-glycans with “high mannose”, “hybrid”, or “complex”…”
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Glycotherapy: A New Paradigm in Breast Cancer Research
Published in Biomolecules (Basel, Switzerland) (23-03-2022)“…Breast cancer is an ancient disease recognized first by the Egyptians as early as 1600 BC. The first cancer-causing gene in a chicken tumor virus was found in…”
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N‐Glycosylation Inhibitor Interferes with WNT Signaling and Inhibits Angiogenesis
Published in The FASEB journal (01-05-2022)“…Neovascularization, a normal physiological process orchestrates through vasculogenesis from mesoderm cell precursors. In healthy adults, the vasculature is…”
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Unfolded Protein Response Is Required in nu/nu Mice Microvasculature for Treating Breast Tumor with Tunicamycin
Published in The Journal of biological chemistry (19-08-2011)“…Up-regulation of the dolichol pathway, a “hallmark” of asparagine-linked protein glycosylation, enhances angiogenesis in vitro. The dynamic relationship…”
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In Vitro Phosphorylation by cAMP-dependent Protein Kinase Up-regulates Recombinant Saccharomyces cerevisiae Mannosylphosphodolichol Synthase
Published in The Journal of biological chemistry (11-02-2005)“…DPM1 is the structural gene for mannosylphosphodolichol synthase (i.e. Dol-P-Man synthase, DPMS) in Saccharomyces cerevisiae. Earlier studies with cDNA cloning…”
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Tunicamycin-induced ER stress in breast cancer cells neither expresses GRP78 on the surface nor secretes it into the media
Published in Glycobiology (Oxford) (01-02-2018)“…Abstract GRP78 (an Mr 78 kDa calcium dependent glucose binding protein) is located in ER lumen. It functions as ER chaperone and translocates proteins for…”
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Dolichol phosphate mannose synthase: a Glycosyltransferase with Unity in molecular diversities
Published in Glycoconjugate journal (01-08-2017)“…N-glycans provide structural and functional stability to asparagine-linked (N-linked) glycoproteins, and add flexibility. Glycan biosynthesis is elaborative,…”
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Tunicamycin-induced ER stress in breast cancer cells neither expresses GRP78 on the surface nor secretes it into the media
Published in Glycobiology (Oxford) (01-07-2019)Get full text
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Speciation of metals in sewage sludge and sludge-amended soils
Published in Water, air, and soil pollution (01-02-2004)“…This study is aimed at ascertaining the chemical partitioning ofCu, Zn, Pb, Ni, Cr and Cd in sewage sludge and agricultural soils repeatedly amended with…”
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Cloning and expression of mannosylphospho dolichol synthase from bovine adrenal medullary capillary endothelial cells
Published in Glycoconjugate journal (01-08-2009)“…Mannosylphospho dolichol synthase (DPMS) is a critical enzyme in the biosynthesis of lipid-linked oligosaccharide (LLO; Glc₃Man₉GlcNAc₂-PP-Dol), a…”
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Balancing life with glycoconjugates: Monitoring unfolded protein response-mediated anti-angiogenic action of tunicamycin by Raman spectroscopy
Published in Pure and applied chemistry (01-01-2012)“…Asparagine-linked protein glycosylation is a hallmark for glycoprotein structure and function. Its impairment by tunicamycin [a competitive inhibitor of…”
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Unique structural motif supports mannosylphospho dolichol synthase: an important angiogenesis regulator
Published in Current drug targets (01-04-2008)“…Mannosylphospho dolichol synthase (DPMS) catalyzes the transfer reaction GDP-mannose + Dol-P <--> Dol-P-Man + GDP, a 'key step' in the assembly of lipid-linked…”
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Potentiation of angiogenic switch in capillary endothelial cells by cAMP: A cross-talk between up-regulated LLO biosynthesis and the HSP-70 expression
Published in Glycoconjugate journal (01-05-2006)“…During tumor growth and invasion, the endothelial cells from a relatively quiescent endothelium start proliferating. The exact mechanism of switching to a new…”
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Low expression of lipid-linked oligosaccharide due to a functionally altered Dol-P-Man synthase reduces protein glycosylation in cAMP-dependent protein kinase deficient Chinese hamster ovary cells
Published in Glycoconjugate journal (01-08-2004)“…Chinese hamster ovary cells express a wide variety of glycoproteins with Mr ranging from 15,000 to 200,000 dalton and higher. Glycosylation of these proteins…”
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Dolicholphosphate Mannosyltransferase: A Glycosyltransferase with Unity in Molecular Diversities
Published in The FASEB journal (01-04-2017)“…Abstract only N‐glycan provides structural and functional stability to glycoproteins and adds to their flexibility. Glycan biosynthesis is elaborative,…”
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Abstract 1007: Nanoformulation enhances anti-angiogenic efficacy of Tunicamycin
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…The breast cancer landscape indicates it is a global problem and accounts for nearly a quarter of all cancers in women. In 2008, 1.4 million women were…”
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DPMS is Essential for Tumor Angiogenesis
Published in The FASEB journal (01-04-2019)“…Dolichol phosphate mannose synthase (DPMS) an inverting GT‐A folded enzyme and classified as GT2 by CAZy (carbohydrate active enZyme; http://www.cazy.org). It…”
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